Therapeutic Insights Into The Pharmacological Actions Of Tinospora Cordifolia (Giloy)

Authors

  • Abhishek Nagar
  • M. K. Gupta
  • Nakul Agrawal

Keywords:

Tinospora cordifolia, herbal suspension, antioxidant activity, phytochemical screening, DPPH assay

Abstract

Tinospora cordifolia (Willd.) Miers, commonly known as Giloy, is a renowned Ayurvedic herb valued for its immunomodulatory, antioxidant, and therapeutic properties. This study aimed to formulate and evaluate an herbal suspension of T. cordifolia by assessing its phytochemical constituents, physicochemical properties, and antioxidant potential. The ethanolic extract was screened for key phytochemicals including alkaloids, flavonoids, and terpenoids. The formulated suspension was evaluated for pH, viscosity, sedimentation, and stability over 90 days. Antioxidant activity was determined using the DPPH assay and compared with ascorbic acid. Results indicated good stability and significant antioxidant potential, supporting its application as a natural therapeutic.

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References

Saha, S., Ghosh, S., & Tinospora cordifolia: A phytopharmacological review. Journal of Pharmacognosy and Phytochemistry, 6(5), 1177–1185. (2017).

Sharma, U., Bala, M., Kumar, N., Singh, B., Munshi, R. K., & Bhalerao, S. Immunomodulatory active compounds from Tinospora cordifolia. Journal of Ethnopharmacology, 141(3), 918–926. (2012).

Upadhyay, A. K., Kumar, K., Kumar, A., & Mishra, H. S. Tinospora cordifolia (Willd.) Hook. f. and Thoms. (Guduchi) – validation of the Ayurvedic pharmacology through experimental and clinical studies. International Journal of Ayurveda Research, 1(2), 112–121. (2010).

Kalikar, M. V., Thawani, V. R., Varadpande, U. K., Sontakke, S. D., & Singh, R. P. Immunomodulatory effect of Tinospora cordifolia extract in human immuno-deficiency virus positive patients. Indian Journal of Pharmacology, 40(3), 107–110. (2008).

Kokate, C. K. Practical Pharmacognosy. Vallabh Prakashan, New Delhi. (2014).

Harborne, J. B. Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis (3rd ed.). Chapman and Hall. (1998).

Indian Pharmacopoeia Commission. Indian Pharmacopoeia. Vol. II, Government of India, Ministry of Health and Family Welfare. Ghaziabad. (2018).

OECD. Guidelines for the Testing of Chemicals – Stability Testing of New Drug Substances and Products. (2004).

Blois, M. S. Antioxidant determinations using a stable free radical. Nature, 181(4617), 1199–1200. (1958).

Martin, A., Swarbrick, J., & Cammarata, A. Physical Pharmacy: Physical Chemical Principles in the Pharmaceutical Sciences (4th ed.). Lippincott Williams & Wilkins. (1993).

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Published

2025-06-05

How to Cite

1.
Nagar A, Gupta MK, Agrawal N. Therapeutic Insights Into The Pharmacological Actions Of Tinospora Cordifolia (Giloy). J Neonatal Surg [Internet]. 2025Jun.5 [cited 2025Jun.20];14(31S):83-90. Available from: https://jneonatalsurg.com/index.php/jns/article/view/7087

Issue

Vol. 14 No. 31S (2025): Journal of Neonatal Surgery

Section

Original Article

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