Phytotherapeutic Potential Of Bauhinia Racemosa In A Topical Lotion For Bacterial Infections
Keywords:
Bauhinia racemosa, antibacterial lotion, phytochemicals, topical formulation, skin infectionAbstract
Introduction: Bacterial skin infections remain a public health challenge, particularly with the rise in antibiotic resistance. Traditional medicinal plants like Bauhinia racemosa have shown promise due to their phytochemical-rich profile and ethnomedicinal relevance.
Objective: This study aimed to formulate and evaluate a topical lotion containing Bauhinia racemosa leaf extract for its antibacterial potential and physiochemical stability.
Methods: Dried Bauhinia racemosa leaves were extracted using ethanol in a Soxhlet apparatus. Phytochemical screening identified flavonoids, tannins, alkaloids, saponins, and terpenoids. Characterization was done using TLC and UV-Visible spectroscopy. The extract was formulated into an oil-in-water lotion and evaluated for pH, viscosity, spreadability, homogeneity, and stability over 90 days. Antibacterial activity was tested using agar well diffusion, disc diffusion, and broth dilution (MIC) methods against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa.
Results: The lotion demonstrated effective antibacterial activity, especially against S. aureus, and retained favorable pH (4.5–6.8), viscosity, and appearance over 90 days. No phase separation or microbial contamination was observed.
Conclusion: The topical formulation of Bauhinia racemosa shows promising antibacterial efficacy and stability, supporting its use as a cost-effective, natural alternative for managing skin infections.
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References
Rashed K, Butnariu M. Antimicrobial and antioxidant activities of Bauhinia racemosa Lam. and chemical content. Iran J Pharm Res. 2014;13(3):1071–7.
Kumar G, Loganathan K, Rao B. Antimicrobial activity of Bauhinia racemosa Lamk. - An in vitro study. Int J Pharm Sci Res. 2010;1(2):79–83.
Nyong B, Dogara F. Profiling phytochemicals of Bauhinia racemosa leaf extracts. Pharmacol J. 2019;11(4):798–803.
Prabhu S, Vijayakumar S, Ramasubbu R, et al. Traditional uses, phytochemistry and pharmacology of Bauhinia racemosa Lam.: a comprehensive review. Future J Pharm Sci. 2021;7(1):101.
Ayaz MM, et al. Phytochemical constituents of Bauhinia racemosa leaves. Int J Pharm Sci Res. 2017;8(11):4697–701.
Khan N, Pande M, Jha KK. Preliminary pharmacognostic evaluations and phytochemical studies on leaves of Bauhinia racemosa (Sonapatti). Int J Biochem Pharmacol. 2019;1(1):12–5.
Nama N, Arora P, Arora N, Jain H. Formulation and Characterization Of Bauhinia Racemosa Extract Loaded Nanoemulsion By Box Behnken Design. Journal of Pharmaceutical Negative Result. 2022;13(08):4950–4958.
Ghumare P, et al. Preliminary phytochemical screening and antibacterial activity of Bauhinia racemosa leaves. Int J Pharm Sci Res. 2013;4(9):3372–6.
Bharti K, Sharma M, Vyas GK, Sharma S. Phytochemical screening of alcoholic extract of Thuja occidentalis leaves for formulation and evaluation of wound healing ointment. Asian J Pharm Res Dev. 2022 Apr 15;10(2):17–22.
Khan N, Pande M, Jha KK. Qualitative And Quantitative Analysis of Ethanolic Extract Of Bauhinia Racemosa By Using Spectroscopic And Chromatographic Techniques. Neuroquantology 2022; 20(17):1716-1720.
Raj M, Vyas GK, Sharma S, Sharma A. Phyto analysis, formulation, and evaluation of herbal lotion produced from Allium Sativum and Phyllanthus Emblica alcoholic extracts. Asian J Pharm Res Dev. 2022 Apr 15;10(2):37–43.
Singh JK, Nama N, Ancheria RK, Jain H. A review on starch-based hydrogel as a carrier of wound healing medicated product. Career Point International Journal of Research(CPIJR) 2022; 1(2): 247-275
Sarkar RI, Nama N, Gupta MK. Evaluation of analgesic activity of ethanol extract of Gyrocarpus Americanus Jacq. Career Point International Journal of Research(CPIJR) 2022; 1(2): 118-139
Vyas GK, Sharma A, Sharma M, Nama N. Poly-herbal formulation on burn wound healing for diabetic albino rats. J Pharm Sci Res. 2023;15(2):213–7.
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