Clinical Spectrum, Etiology And Outcomes Of Pediatric Pancreatitis: A Tertiary Care Experience
Keywords:
Pediatric pancreatitis, Kashmir, Drug induced pancreatitis, Choledochal cystAbstract
Background: Pancreatitis in children is an increasingly recognized condition with diverse etiologies and clinical presentations. This study aims to evaluate the spectrum of pediatric pancreatitis in a cohort of 30 children.
Methods: A prospective analysis was conducted on 30 pediatric patients diagnosed with pancreatitis in departments of Gastroenterology and General surgery, GMC Srinagar Kashmir from Dec 2018 to Dec 2023. Data on demographics, clinical presentation, laboratory findings, imaging characteristics, etiology, management, and outcomes were collected and analyzed.
Results: The median age of the patients was 12 years, with a male-to-female ratio of 1.5:1. The most common presenting symptoms were abdominal pain (90%), vomiting (72%), and fever (60%). Etiologies included idiopathic (33%), biliary (20%), trauma-related (13%) metabolic causes (13%) and medication-induced (6%).Serum amylase and lipase were elevated in 73% and 83% of cases. Imaging revealed pancreatic enlargement in 66% and necrotizing pancreatitis in 33.33% of cases. Management strategies varied, including supportive care (65%), nutritional interventions (13%), and specific etiological treatments (36.66%). The overall recovery rate was 100%.
Conclusion: Pediatric pancreatitis presents with a wide clinical spectrum, requiring a thorough diagnostic approach to determine the underlying etiology. Early recognition and appropriate management can improve outcomes. Further studies with larger cohorts are needed to enhance understanding and optimize treatment protocols.
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Morinville VD, Husain SZ, Bai H, Barth B, Alhosh R, Durie PR, et al. Definitions of pediatric pancreatitis and survey of present clinical practices. J Pediatr Gastroenterol Nutr. 2012;55(3):261-5.
Park AJ, Latif SU, Shah AU, Tian J, Haberland CA, Werlin SL, et al. Changing epidemiology of acute pancreatitis hospitalizations: A 15-year national study. Pediatrics. 2010;125(3):e1035-41.
Pant C, Deshpande A, Olyaee M, Sferra TJ, Gilroy R, Almadhoun O, et al. Epidemiology of acute pancreatitis in hospitalized children in the United States from 2000–2009. PLoS One. 2014;9(5):e95552.
Werlin S, Kugathasan S, Frautschy BC. Pancreatitis in children. J Pediatr Gastroenterol Nutr. 2003;37(2):128-34.
Bai HX, Lowe ME, Husain SZ. What have we learned about acute pancreatitis in children? J Pediatr Gastroenterol Nutr. 2011;52(3):262-70.
Schwarzenberg SJ, Bellin MD, Husain SZ, Ahuja M, Barth B, Davis H, et al. Pediatric chronic pancreatitis: Recommendations from the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Pancreas Committee. J Pediatr Gastroenterol Nutr. 2018;66(1):159-76.
Ooi CY, Dorfman R, Cipolli M, Gonska T, Castellani C, Keenan K, et al. Type of CFTR mutation determines risk of pancreatitis in patients with cystic fibrosis. Gastroenterology. 2011;140(1):153-61.
Kumar S, Ooi CY, Werlin S, Abu-El-Haija M. Risk factors associated with pediatric acute recurrent and chronic pancreatitis: Lessons from INSPPIRE. JAMA Pediatr. 2016;170(6):562-9
Gariepy CE, Heyman MB. Pancreatitis in childhood. Curr Opin Gastroenterol. 2014;30(5):508-13.
Nydegger A, Couper RT, Oliver MR. Childhood pancreatitis. J Gastroenterol Hepatol. 2006;21(4):499-509.
Giefer MJ, Lowe ME. Pediatric pancreatitis. Curr Opin Gastroenterol. 2017;33(5):451-6.
Párniczky A, Mosztbacher D, Hanák L, Szűcs Á, Almási-Nagy G, Cseh A, et al. Pediatric pancreatitis: Multicenter international survey on the management of acute pancreatitis in children. Pancreatology. 2016;16(3):358-64.
Abu-El-Haija M, Kumar S, Szabo F, Werlin S, Conwell DL, Gariepy C, et al. Classification of acute pancreatitis in the pediatric population: Clinical report from the NASPGHAN Pancreas Committee. J Pediatr Gastroenterol Nutr. 2017;64(1):120-31
Pant C, Deshpande A, Olyaee M, Anderson MP, Bitar A, Steele MI, et al. Hospitalizations for chronic pancreatitis in children: A national 15-year study. J Pediatr Gastroenterol Nutr. 2016;62(3):450-5.
Takahashi K, Suzuki M, Ichihashi T, Koyama K. Acute pancreatitis in children: A 10-year experience. Hepatogastroenterology. 2012;59(114):329-31. 16. Uc A, Husain SZ. Pancreatitis in children. Gastroenterology. 2019;156(7):1969-78.
Liu L, Fagundes-Neto U, Granato CF. Pediatric acute pancreatitis: A multicenter study of 147 cases in Brazil. Pancreatology. 2020;20(4):646-52.
Hegyi E, Sahin-Tóth M. Genetic risk in chronic pancreatitis: The trypsin-dependent pathway. Dig Dis Sci. 2017;62(7):1692-701.
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