Green and chemical synthesis of silver nanoparticles: Study of biological properties and toxicity concerns related to chemically synthesized nanoparticles

Authors

  • Pradnya Salunkhe
  • Tushar Borse
  • Girish Pathade
  • Dhanashri Patil

Keywords:

Antibacterial potential, Antifungal properties,, Green chemistry, Silver nanoparticles

Abstract

Metallic nanoparticles, particularly silver nanoparticles, are widely used in science, engineering, and medicine due to their small size. However, conventional synthesis methods pose biological hazards, prompting the development of environmentally friendly methods like green synthesis using plant-derived components. Present study used eco-friendly, cost efficient and easy method for synthesis of silver nanoparticles (AgNPs) using Withania somnifera extracts as reducing and capping agents. In another approach, chemical synthesis of AgNPs has been carried out using tri-sodium citrate and polyethylene glycol as reducing agents. Measurement on UV-Vis absorption spectroscopy at 415 nm confirmed the synthesis of AgNPs in the solution. Both the AgNPs were tested for their antibacterial properties against Bacillus subtilis, antioxidant and antifungal properties against A. niger. The chemically synthesized AgNPs were tested on the seed germination of Zea mays for detecting their toxic effect. Moreover, the treated plantlets were also evaluated for their protein and chlorophyll content and results confirmed that as the concentration of chemically synthesized AgNPs increases the growth of the Zea mays plantlet decreases

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Ahmed S, Ahmad M, Swami BL, Ikram S (2016) A review on plants extract mediated synthesis of silver nanoparticles for antimicrobial applications. J Adv Res 7:17- 28

Albrecht AM, Evans CW, Raston CL (2006) The health implications of nanoparticles. Green Chem 8:417-432

Ashraf JM, Ansari MA, Khan HM, Alzohairy MA, Choi I (2016) Green synthesis of silver nanoparticles characterization of their inhibitory effects on AGEs formation using biophysical techniques. Sci Rep 6:20414

Bryan CJ, Monique EJ, Antonio RMB, Karen EM, Michael RW, José RVB (2017) Silver Nanoparticles: Technological Advances, Societal Impacts Metrological Challenges. Front Chem

Chaloupka K, Malam Y, Seifalian AM (2010) Nano-silver as a new generation of nano-product in biomedical applications. Trends Biotechnol 28:580-8

Jeong S, Yeo S, Yi S. (2005) J Mater Sci 40:5407.

Nejatzadeh-Barandozi F, (2013) Antibacterial activities and antioxidant capacity of Aloe vera. Org Med Chem Lett 3:5

Suman TY, Radhika Rajasree SR, Kanchana A Elizabeth SB (2013) Biosynthesis, characterization and cytotoxic effect of plant mediated silver nanoparticles using Morinda citrifolia root extract. Colloids Surf B Biointerfaces 106: 74-8.

Downloads

Published

2025-05-05

How to Cite

1.
Salunkhe P, Borse T, Pathade G, Patil D. Green and chemical synthesis of silver nanoparticles: Study of biological properties and toxicity concerns related to chemically synthesized nanoparticles. J Neonatal Surg [Internet]. 2025May5 [cited 2025Sep.21];14(20S):667-74. Available from: https://jneonatalsurg.com/index.php/jns/article/view/5103

Issue

Vol. 14 No. 20S (2025): Journal of Neonatal Surgery

Section

Original Article

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

You are free to:

  • Adapt — remix, transform, and build upon the material for any purpose, even commercially.

Terms:

  • Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.