Can Adhd Present In Dyke-Davidoff-Masson Syndrome? A Case Report
DOI:
https://doi.org/10.52783/jns.v14.3859Keywords:
N\AAbstract
Background: Dyke-Davidoff-Masson Syndrome (DDMS) is an uncommon neurological disorder primarily characterized by unilateral cerebral hemiatrophy with compensatory cranial changes. Clinical manifestations typically include seizures, hemiparesis, and developmental delays. While various neuropsychiatric presentations have been sporadically reported, the occurrence of Attention-Deficit/Hyperactivity Disorder (ADHD) as a comorbidity remains undocumented.
Case Presentation: We describe a 4-year-old boy with a known diagnosis of DDMS since birth who subsequently developed generalized tonic-clonic seizures and, independently, began exhibiting cardinal features of ADHD—namely inattention, hyperactivity, and impulsivity. These symptoms persisted even after seizure control was achieved. Neuroimaging revealed the classic structural hallmarks of DDMS, including left-sided cerebral atrophy, ipsilateral ventricular dilatation, and a notable midline shift. Following multidisciplinary evaluation, the child was started on methylphenidate for ADHD, despite concerns regarding a lowered seizure threshold. This therapeutic approach led to significant behavioral improvement with no recurrence of seizures.
Conclusion: This case highlights a previously unreported association between DDMS and ADHD, underscoring the importance of broad, individualized management strategies in children with structural brain anomalies. Further research is warranted to clarify the shared neurobiological pathways and refine treatment options for this rare co-occurrence
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