Retrospective Analysis of Premature Infant Characteristics: Risk Factors, Complications, and Predictive Insights

Authors

  • Meghana Hegde
  • Prakash Padakannaya

DOI:

https://doi.org/10.52783/jns.v14.1943

Keywords:

Preterm birth, Neonatal morbidity, Risk factors, Predictive insights, Perinatal influences

Abstract

Premature birth remains a significant global health challenge, contributing to high rates of neonatal morbidity and mortality. This retrospective study analyzes the key characteristics, risk factors, complications, and predictive outcomes affecting preterm infant outcomes. Utilizing established theoretical frameworks—including the Developmental Origins of Health and Disease (DOHaD), the Bioecological Model, and the Neurodevelopmental Framework this research examines the interplay of prenatal, perinatal, and postnatal influences on neonatal health. A comprehensive analysis of neonatal morbidity trends from 2018 to 2020 highlights both advancements and persistent challenges in neonatal care. By integrating clinical data with theoretical insights, this study provides a refined understanding of the factors influencing preterm infant health. The findings offer valuable implications for improving neonatal risk assessment models, optimizing clinical interventions, and enhancing long-term developmental outcomes for preterm infants.

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References

Adams-Chapman, I., Bann, C. M., Carter, S. L., & Stoll, B. J. (2013). Neurodevelopmental outcome of the late preterm infant. Clinics in Perinatology, 40(4), 739–751. https://doi.org/10.xxxx

Bancalari, E., & Claure, N. (2012). Respiratory outcomes in preterm infants. Seminars in Fetal and Neonatal Medicine, 17(6), 337–341. https://doi.org/10.xxxx

Barker, D. J. P. (2007). The origins of the developmental origins theory. Journal of Internal Medicine, 261(5), 412–417. https://doi.org/10.xxxx

Blencowe, H., Cousens, S., Oestergaard, M. Z., Chou, D., Moller, A. B., Narwal, R., Adler, A., Vera Garcia, C., Rohde, S., Say, L., & Lawn, J. E. (2013). Born too soon: The global epidemiology of 15 million preterm births. Reproductive Health, 10(S1), S2. https://doi.org/10.xxxx

Bronfenbrenner, U. (1979). The ecology of human development: Experiments by nature and design. Harvard University Press.

Gardner, S. L., Carter, B. S., Enzman-Hines, M., & Hernández, J. A. (2016). Merenstein & Gardner’s handbook of neonatal intensive care (8th ed.). Elsevier.

Gluckman, P. D., Hanson, M. A., Cooper, C., & Thornburg, K. L. (2008). Effect of in utero and early-life conditions on adult health and disease. New England Journal of Medicine, 359(1), 61–73. https://doi.org/10.xxxx

Jobe, A. H. (2012). The new bronchopulmonary dysplasia. Current Opinion in Pediatrics, 24(2), 179–186. https://doi.org/10.xxxx

Kinney, H. C. (2009). The encephalopathy of prematurity: One pediatric neuropathologist’s perspective. Seminars in Pediatric Neurology, 16(4), 179–190. https://doi.org/10.xxxx

March of Dimes. (2020). Premature birth report card. Retrieved from http://www.marchofdimes.org

Monroe, S. M., & Simons, A. D. (1991). Diathesis-stress theories in the context of life stress research. Psychological Bulletin, 110(3), 406–425. https://doi.org/10.xxxx

Roberts, D., & Dalziel, S. (2006). Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. *Cochrane Database of Systematic Reviews, (3), CD004454. https://doi.org/10.xxxx

Saigal, S., & Doyle, L. W. (2008). An overview of mortality and sequelae of preterm birth from infancy to adulthood. The Lancet, 371(9608), 261–269. https://doi.org/10.xxxx

Thelen, E., & Smith, L. B. (1994). A dynamic systems approach to the development of cognition and action. MIT Press.

Volpe, J. J. (2009). Brain injury in premature infants: A complex amalgam of destructive and developmental disturbances. The Lancet Neurology, 8(1), 110–124. https://doi.org/10.xxxx

World Health Organization [WHO]. (2018). Preterm birth. Retrieved from http://www.who.int

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Published

2025-03-05

How to Cite

1.
Hegde M, Padakannaya P. Retrospective Analysis of Premature Infant Characteristics: Risk Factors, Complications, and Predictive Insights. J Neonatal Surg [Internet]. 2025Mar.5 [cited 2025Sep.21];14(4S):1269-74. Available from: https://jneonatalsurg.com/index.php/jns/article/view/1943