Comparative Evaluation of The Remineralizing Potential of Three Commercially Available Dentifrices On Artificial Carious Lesions: In-Vitro Study

Authors

  • Sejal S. Shah
  • Nilesh Rathi
  • Milind Rajan
  • Shikha Sharma
  • Shruti Shampa
  • Suganya Mahadeva

Keywords:

Dental Caries, Fluoride, Remineralization

Abstract

The study aims to evaluate and compare the remineralizing potential of three commercially available dentifrices with varying fluoride concentrations on artificial carious lesions, utilizing Vicker's Microhardness Number (VHN) as a primary measurement tool. Inclusion criteria for the study required the use of extracted premolars with sound, intact crowns, while exclusion criteria eliminated teeth with developmental defects, existing caries, restorations, fractures, or those previously subjected to pulp therapy. A total of 21 extracted premolar teeth were sourced from the Department of Oral and Maxillofacial Surgery at Dr. D Y Patil Vidyapeeth’s Dental College, Pune. The dentifrices tested included Dente91® Cool Mint Toothpaste containing Nano-Hydroxyapatite and xylitol, Jordan* Junior Toothpaste (6-12 years) with sodium fluoride, and Colgate® Total Advanced Health Anticavity Toothpaste with 0.24% sodium fluoride and triclosan. Microhardness of teeth samples treated with Dente91 Cool Mint, Jordan Junior TMMC (1450 ppm), and Colgate Total Advanced Anticavity Toothpaste (n=14 each) was measured using a Reichert tester. Baseline values were 324 HV (Group 1), 328 HV (Group 2), and 330 HV (Group 3). After 96 hours of demineralization, values dropped to 261 HV (Group 1), 277 HV (Group 2), and 258 HV (Group 3). Group 2 showed the highest resistance to demineralization, while Group 3 had the lowest hardness.

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Published

2025-07-28

How to Cite

1.
Shah SS, Rathi N, Rajan M, Sharma S, Shampa S, Mahadeva S. Comparative Evaluation of The Remineralizing Potential of Three Commercially Available Dentifrices On Artificial Carious Lesions: In-Vitro Study. J Neonatal Surg [Internet]. 2025Jul.28 [cited 2025Sep.20];14(9S):971-5. Available from: https://jneonatalsurg.com/index.php/jns/article/view/8581