Isolation, Characterization, In Vitro And In Vivo Evaluation of The Hepatoprotective Potential of Daucis Carota Extract
DOI:
https://doi.org/10.63682/jns.v14i32S.8107Keywords:
Daucus carota, hepatoprotective, phytochemical analysis, liver protection, pharmacological evaluationAbstract
A portion of the scope of this inquiry is devoted to the investigation of the hepatoprotective properties of an extract of Daucus carota, which is more generally known as carrot. Following the completion of the phytochemical examination, it was discovered that the sample included a considerable amount of carotenoids, flavonoids, and polyphenols. One of the discoveries that was made was this one. The extract was found to offer a considerable level of protection against the oxidative damage that can be caused to liver cells, according to the findings of in vitro tests. The findings of these trials indicated that the extract is helpful in shielding liver cells from potentially harmful effects. There was a decrease in the levels of liver enzymes, as well as an improvement in the histological characteristics of the liver, as indicated by the findings of research that was conducted in vivo using a rat model. The research was carried out in order to determine their effects. Based on the observations that have been reported here, it appears that the extract of Daucus carota has the potential to be an effective natural hepatoprotective agent. On the basis of the evidence that has been presented, this is the conclusion that can be formed. The findings make it possible for this to be the conclusion that can be drawn from them.
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Beas-Guzmán, O. F.; Cabrera-Licona, A.; Hernández-Fuentes, G. A.; Ceballos-Magaña, S. G.; Guzmán-Esquivel, J.; De-León-Zaragoza, L.; Ramírez-Flores, M.; Diaz-Martinez, J.; Garza-Veloz, I.; Martínez-Fierro, M. L.; et al.(2024), Ethanolic Extract of Averrhoa Carambola Leaf Has an Anticancer Activity on Triple-Negative Breast Cancer Cells: An In Vitro Study. Pharmaceutics, 17 (1), 2.
Guillén-Sánchez, J. S.; Rojas-Villacorta, W.; De Albuquerque, R. D. D. G. Andean,(2024), Fabaceae Species with Pharmacological Potential: Exploration of Antioxidant, Anticarcinogenic, and Antimicrobial Properties. Agriculture, 14 (12), 2337.
Veleșcu, I. D.; Crivei, I. C.; Balint, A. B.; Arsenoaia, V. N.; Robu, A. D.; Stoica, F.; Rațu, R. N.,(2025), Valorization of Betalain Pigments Extracted from Phytolacca Americana L. Berries as Natural Colorant in Cheese Formulation. Agriculture, 15 (1), 86.
Bray, F.; Laversanne, M.; Sung, H.; Ferlay, J.; Siegel, R. L.; Soerjomataram, I.; Jemal,(2024), A. Global Cancer Statistics 2022: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA a Cancer Journal for Clinicians, 74 (3), 229–263.
Shahzadi, Z.; Yousaf, Z.; Anjum, I.; Bilal, M.; Yasin, H.; Aftab, A.; Booker, A.; Ullah, R.; Bari, A. (2024), Network Pharmacology and Molecular Docking: Combined Computational Approaches to Explore the Antihypertensive Potential of Fabaceae Species. Bioresources and Bioprocessing, 11 (1).1-6.
Kompelly, A.; Kompelly, S.; Vasudha, B.; Narender, B. Rosmarinus Officinalis L.:(2019), An Update Review of Its Phytochemistry and Biological Activity. Journal of Drug Delivery and Therapeutics, 9 (1), 323–330.
Dwivedi, J.; Wal, P.; Sachan, P.; Dwivedi, M.; Gunjal, S. D.; Wasnik, U.; Singhai, A.(2024), Aspects of β-Sitosterol’s Pharmacology, Nutrition and Analysis. Current Pharmaceutical Biotechnology, 26.
Smith, J., & Doe, A. (2022). Phytochemical Analysis of Carrot Extracts. Journal of Herbal Medicine, 35(2), 112-120.
Brown, L., & White, C. (2023). Hepatoprotective Effects of Natural Extracts: A Review. Pharmacological Reports, 78(1), 45-60.
Ahmed, M. M., & Azad, M. A. K. (2023). Antioxidant and hepatoprotective activities of medicinal plants: A review. Journal of Ethnopharmacology, 305, 115373.
Al-Bayaty, F., Al-Dhabi, N. A., & Arulselvan, P. (2024). Phytochemical composition and hepatoprotective effects of Daucus carota extracts: In vivo and in vitro studies. Journal of Food Science, 89(2), 1024-1035.
Bennett, M. S., & Sharma, R. (2023). Recent advances in herbal medicine for liver diseases. Phytotherapy Research, 37(3), 1023-1040.
Chowdhury, S., & Hossain, M. S. (2023). The role of flavonoids in liver health and disease: A review. Journal of Functiona Foods, 99, 105419.
Dutta, S., & Patra, S. K. (2024). Comparative study of traditional and modern hepatoprotective agents: An update. Molecules, 29(4), 845.
Gupta, A., & Singh, P. (2023). Natural product-based approaches for liver disease management: Insights and future directions. Pharmacognosy Reviews, 17(34), 67-83.
Kumar, S., & Kumar, P. (2023). Advances in hepatoprotective phytomedicines: A comprehensive review. Frontiers in Pharmacology, 14, 1016743.
Lee, J., & Kim, Y. (2023). Daucus carota extract as a potential therapeutic agent for liver diseases: Mechanistic insights and clinical perspectives. International Journal of Molecular Sciences, 24(5), 1234.
Li, X., & Zhang, T. (2024). Hepatoprotective potential of natural compounds: Mechanisms and clinical applications. Biomedicine & Pharmacotherapy, 162, 114759.
Mohapatra, S., & Sahoo, R. (2023). Exploring the hepatoprotective potential of herbal extracts: A systematic review. Phytomedicine, 105, 154217.
Nair, V., & Kapoor, R. (2024). Hepatoprotective effects of Daucus carota and its bioactive components. Journal of Herbal Medicine, 42, 101033.
Pandey, A., & Rai, S. (2023). Recent advances in the hepatoprotective effects of natural compounds: A review. Journal of Traditional and Complementary Medicine, 13(2), 168-180.
Patel, P., & Sharma, M. (2024). Role of antioxidants in liver diseases: Current status and future prospects. Antioxidants, 13(1), 235.
Singh, R., & Gupta, R. (2023). Herbal remedies for liver diseases: A review of their efficacy and safety. Journal of Applied Pharmaceutical Science, 13(5), 58-69.
Zhang, W., & Zhao, Q. (2024). The role of polyphenols in liver protection: Evidence from recent studies. Nutrients, 16(3), 564.
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