Antibacterial Activity Of Jatropha Curcas Sap Against Staphylococcus Aureus
Keywords:
Antibacterial, Jatropha curcas Sap, Staphylococcus aureusAbstract
Jatropha curcas is a plant that has long been known by the community as a border or hedge plant, a source of medicine, and a producer of oil for lamps. The sap plant contains various chemical compounds, including flavonoids, tannins, saponins, and jatrophine, which also show antibacterial and antifungal activity. One of the common bacteria in the human body is Staphylococcus aureus, which is associated with pyogenic infections, especially those that attack the skin. Staphylococcus aureus is one of the most common infectious agents, which enters the skin through hair follicles, sweat glands, or small wounds. The purpose of this study was to investigate the effect of Jatropha curcas L. on the growth of Staphylococcus aureus bacteria. This study was designed as a true experimental study, which aims to determine the symptoms or effects resulting from certain treatments. Preparation of Jatropha curcas L. sap with a concentration of 25% v/v. Required 025 ml of Jatropha curcas L. sap with a concentration of 100% v/v and 0.75 ml of sterile distilled water. Preparation of Jatropha curcas L. sap with a concentration of 50% v/v. Required 0.5 ml of Jatropha curcas L. sap with a concentration of 100% w/v and 0.5 ml of sterile distilled water. Preparation of Jatropha curcas L. sap with a concentration of 75% v/v. Required 0.75 ml of Jatropha curcas L. sap with a concentration of 100% w/v and 0.25 ml of sterile distilled water. The results showed that the 25% concentration of J. curcas sap had an inhibition zone of 21.75 mm, the 50% concentration had an inhibition zone of 22.63 mm, the 75% concentration had an inhibition zone diameter of 24.13 mm, and the 100% concentration had an inhibition zone diameter of 24.75 mm. The conclusion showed that the higher the concentration of Jatropha curcas sap, the larger the diameter of the inhibition zone, this indicates a significant effect on the growth of Staphylococcus aureus bacteria.
Downloads
References
Abdelgadir, H. A., & Van Staden, J. (2013). Ethnobotany, ethnopharmacology and toxicity of Jatropha curcas L. (Euphorbiaceae): A review. South African Journal of Botany, 88, 204–218. https://doi.org/10.1016/j.sajb.2013.07.021
Abubakar, S., Akanbi, B. O., Osuji, C., Olajide, O. O., & Philip, E. A. (2016). Evaluation of pharmacological potentials of Jatropha curcas Linn sap Euphobiaceae family. Pharmaceutical and Biological Evaluations, 3(3), 334–342.
Adeiza, Z. D., Olaitan, C. O., Emmanuel, E., Israel, O. A., & Danjuma, S. Y. (2024). Antimicrobial Activity of Jatropha Curcas Sap on Selected Microorganisms. Journal of Traditional Medicine & Applications, 3(1), 01–06.
Afzal, M., Kazmi, I., Khan, R., Singh, R., Chauhan, M., & Bisht, T. (2012). Bryophyllum Pinnatum: A Review. International Journal of Biological Sciences, 2(4), 143–149.
Akinpelu, D. A., Aiyegoro, O. A., & Okoh, A. I. (2009). The bioactive potentials of two medicinal plants commonly used as folklore remedies among some tribes in West Africa. African Journal of Biotechnology, 8(8), 1660–1664.
Akiyama, H. (2001). Antibacterial action of several tannins against Staphylococcus aureus. Journal of Antimicrobial Chemotherapy, 48(4), 487–491. https://doi.org/10.1093/jac/48.4.487
Alina, P., Kiełb Ewa, P., & Frantis ek, Z. (2023). Antimicrobial activity of saponin-containing plants: Review. Journal of Dairy, Veterinary & Animal Research, 12(2), 121–127. https://doi.org/10.15406/jdvar.2023.12.00336
Arekemase, M. O., Kayode, R. M. O., & Ajiboye, A. E. (2011). Antimicrobial Activity and Phytochemical Analysis of Jatropha Curcas Plant against Some Selected Microorganisms. International Journal of Biology, 3(3), p52. https://doi.org/10.5539/ijb.v3n3p52
Notoatmodjo, S. 2002, Metodologi Penelitian Kesehatan, Rineka Cipta, Jakarta Omoregie, E., & Folashade, K. (2013). Broad Spectrum Antimicrobial Activity of Extracts of Jatropha curcas. Journal of Applied Pharmaceutical Science, 3(4), 083–087.
Omoregie, E. H., & Folashade, K. O. (2013). Broad Spectrum Antimicrobial Activity of Extracts of Jatropha curcas. Journal of Applied Pharmaceutical Science, 3(4), 083–087.
Patil, D., Roy, S., Dahake, R., Rajopadhye, S., Kothari, S., Deshmukh, R., & Chowdhary, A. (2013). Evaluation of Jatropha curcas Linn. Leaf extracts for its cytotoxicity and potential to inhibit hemagglutinin protein of influenza virus. Indian Journal of Virology: An Official Organ of Indian Virological Society, 24(2), 220–226.https://doi.org/10.1007/s13337-013-0154-z
Payne, D. E., Martin, N. R., Parzych, K. R., Rickard, A. H., Underwood, A., & Boles, B. R. (2013). Tannic acid inhibits Staphylococcus aureus surface colonization in an IsaA-dependent manner. Infection and Immunity, 81(2), 496–504. https://doi.org/10.1128/IAI.00877-12
Prasad, D. M. R. (2012). Jatropha curcas: Plant of medical benefits. Journal of Medicinal Plants Research, 6(14). https://doi.org/10.5897/JMPR10.977
Rachana, S., Agarwal, T., Rastogi, R., Arora, N., & Rastogi, M. (2012). Comparative Analysis of Antibacterial Activity of Jatropha curcas Fruit Parts. Journal of Pharmaceutical and Biomedical Sciences, 15(15), 1–4.
Rampadarath, S., Puchooa, D., & Jeewon, R. (2016). Jatropha curcas L: Phytochemical, antimicrobial and larvicidal properties. Asian Pacific Journal of Tropical Biomedicine, 6(10), 858–865. https://doi.org/10.1016/j.apjtb.2016.01.019
Thomas, R., Sah, N., & Sharma, P. (2008). Therapeutic Biology of Jatropha curcas: A Mini Review. Current Pharmaceutical Biotechnology, 9(4), 315–324. https://doi.org/10.2174/138920108785161505
Villanueva, X., Zhen, L., Ares, J. N., Vackier, T., Lange, H., Crestini, C., & Steenackers, H. P. (2023). Effect of chemical modifications of tannins on their antimicrobial and antibiofilm effect against Gram-negative and Gram-positive bacteria. Frontiers in Microbiology, 13, 987164. https://doi.org/10.3389/fmicb.2022.987164
Yan, Y., Li, X., Zhang, C., Lv, L., Gao, B., & Li, M. (2021). Research Progress on Antibacterial Activities and Mechanisms of Natural Alkaloids: A Review. Antibiotics, 10(3), 318. https://doi.org/10.3390/antibiotics10030318
Downloads
Published
How to Cite
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
Terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.