Efficacy of Topical Glucosamine in Oral Lichen Planus

Authors

  • Sara A. Galala
  • Nevine H Kheir El Din
  • Shahira Al Ashiry
  • Hala El-kammar
  • Asmaa M. Elbakry
  • Ola M. Ezzatt

Keywords:

Oral lichen planus, Glucosamine

Abstract

Lichen planus (LP) is a chronic, immune-mediated, inflammatory condition that can affect the skin, nails, and mucous membranes. Oral lichen planus (OLP) is the mucosal counterpart, presenting as white, reticular lesions (asymptomatic) or erythematous erosions (symptomatic) that can cause symptoms ranging from spontaneous soreness to severe pain interfering with eating, speech, swallowing, and patients' daily activities.

Treatment strategies for OLP vary depending on the severity and extent of the lesions. Despite this, corticosteroids remain the cornerstone of management; various treatment modalities have also been introduced and used, particularly in refractory cases. Glucosamine (GlcN) is an amino sugar that plays a crucial role in the synthesis of essential components of cartilage and connective tissue. It has anti-inflammatory and immunomodulatory effects. This is a case of successful management of symptomatic OLP with GlcN as a promising treatment modality for OLP.

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Published

2025-06-25

How to Cite

1.
Galala SA, El Din NHK, Al Ashiry S, El-kammar H, M. Elbakry A, M. Ezzatt O. Efficacy of Topical Glucosamine in Oral Lichen Planus. J Neonatal Surg [Internet]. 2025Jun.25 [cited 2025Jul.12];14(32S):2041-6. Available from: https://jneonatalsurg.com/index.php/jns/article/view/7699

Issue

Vol. 14 No. 32S (2025): Journal of Neonatal Surgery

Section

Original Article

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