Impact Of Caffeine and Decaffeinated Coffee on Blood Glucose Levels in Healthy Individuals And Type 2 Diabetes Patients on Antidiabetic Medication
Keywords:
Caffeine, Decaffeinated coffee, Glycemic control, Type 2 diabetes mellitus, Antidiabetic medicationAbstract
Background: Coffee is among the most commonly consumed beverages worldwide, yet its effects on glycemic control remain debated. While caffeine may acutely impair insulin sensitivity, decaffeinated coffee contains bioactive compounds potentially beneficial for glucose metabolism. This randomized controlled trial aimed to assess and compare the effects of caffeinated and decaffeinated coffee on glycemic parameters in healthy individuals and patients with type 2 diabetes mellitus (T2DM) on oral antidiabetic medications.
Methods: Conducted over three months at Astra Speciality Hospital, Chennai, the study enrolled 60 participants, equally divided into two groups: Group A (healthy individuals) and Group B (T2DM patients). Each group was further randomized to receive either caffeinated or decaffeinated coffee daily. Fasting blood sugar (FBS), postprandial blood sugar (PPBS), random blood sugar (RBS), and HbA1c were recorded at baseline and at study completion.
Results: In healthy participants, caffeinated coffee led to significant increases in all glycemic markers, while decaffeinated coffee showed slight improvements. Among T2DM patients, both coffee types improved glycemic control, but the decaffeinated group exhibited significantly greater reductions, especially in HbA1c.
Conclusion: Decaffeinated coffee may support better glycemic outcomes than caffeinated coffee in both healthy individuals and those with T2DM. These findings support incorporating coffee type into personalized dietary guidance for metabolic health.
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