Efficacy of an intensive lifestyle modification program on anthropometric measurements and gulcose parameters in the middle aged prediabetic population of Karad
Keywords:
Prediabetes, fasting blood glucose, anthropometric measurements, and lifestyle modificationAbstract
Background: Prediabetes is a metabolic disorder marked by high blood glucose levels that does not match the criteria for diabetes diagnosis. It is linked to insulin resistance, a condition of poor glucose metabolism which results from reduced insulin sensitivity in the muscles and liver. The pathophysiological markers of prediabetes include insulin resistance and poor glucose tolerance, which can be brought on by the confluence of behavioural, environmental, and genetic variables. Chronic insulin resistance declines insulin output over time by causing beta-cell dysfunction in the pancreas. This progression elevates the risk of type 2 diabetes and its associated dangers, such as neuropathy and cardiovascular disorders. A first-line strategy to lower the risk of type 2 diabetes is an intensive lifestyle modification program, which involves diet adjustments and planned physical activities. This study aims to evaluate the effectiveness of an intensive lifestyle modification program in middle-aged prediabetic population based on anthropometric measurements and glucose parameters.
Methodology: A quasi-experimental study was conducted to evaluate the efficacy of an intensive lifestyle modification program consisting of aerobic training and resistance exercises, dietary changes. One hundred and fifty-three participants were enrolled in the study. Anthropometric assessments included BMI and waist-to-hip ratio (WHR), glucose parameters included measures of fasting blood glucose levels, psychological stress was calculated using the Perceived Stress Scale-10 questionnaire, while the physical activity levels were measured using the IPAQ-SF questionnaire. Chi-square and paired t-tests were used to analyse data before and after the intervention.
Results: The sample included 153 participants. At 6 months, the participants demonstrated a significant improvement in fasting blood glucose, body mass index (BMI), waist-to-hip ratio, perceived stress, and physical activity levels (p<0.05)
Conclusion: Anthropometric and glycaemic indices, stress levels, and physical activity are all markedly improved in the middle-aged prediabetic population by the rigorous lifestyle change program. According to these results, systematic lifestyle interventions are crucial as a non-pharmacological approach to halting the progression from prediabetes to type 2 diabetes.
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