Evaluation Levels of Interleukins in Rheumatoid Arthritis and treatment with Senegalia senegal (gum Arabic) and Boswellia

Authors

  • Basma Ali Jasim
  • Alia Hussein Ali

Keywords:

Arthritis, Boswellia, Gum Arabic, Interleukins, TNF-α

Abstract

This study aimed to explain the effect of Senegalia Senegal (Gum Arabic) and Boswellia on some Interleukin. Thirty adult male rats were used after induction of arthritis. They were divided into six groups, with five rats for each group. The first group was the negative control group (rats without arthritis induction and treatment), the second group was the positive control group (rats with arthritis induction), the third group was (the group arthritis induction and intubated orally with 250 mg kg B.W Boswellia), the fourth group was (the group arthritis induction and intubated orally 400 mg/kg B.W. gum arabic), and the fifth group was (the group arthritis induction and intubated orally with Boswellia and gum arabic). The sixth group was arthritis induction and intubated 0.75 mg/kg of methotrexate. Blood samples were obtained after two and six weeks. to tests were Interleukins IL-6, IL-1,IL-10, IL-2 and TNF-α   in comparison to two weeks and six weeks for one group.  The study indicated a significant increase in IL-6, IL-1, and TNF-α after two weeks and after six weeks, while IL-10 showed a significant decrease after two weeks and an increase after six weeks in as comparing with group G0.

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Published

2025-05-13

How to Cite

1.
Jasim BA, Ali AH. Evaluation Levels of Interleukins in Rheumatoid Arthritis and treatment with Senegalia senegal (gum Arabic) and Boswellia. J Neonatal Surg [Internet]. 2025May13 [cited 2025Oct.14];14(21S):1463-70. Available from: https://jneonatalsurg.com/index.php/jns/article/view/5742

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Vol. 14 No. 21S (2025): Journal of Neonatal Surgery

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Original Article

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