Primary Localized Ocular Amyloydosis: A Rare Case Report
Keywords:
Non-hereditary Amyloidosis, Bilateral Ocular Amyloidosis, Ocular Amyloidosis, Isolated Amyloidosis, AmyloidosisAbstract
Introduction: Amyloidosis is a complex, heterogeneous set of illnesses characterized by the deposition of hyaline extracellular material into many tissues throughout the body, including the eye and ocular adnexa. Therefore, we would like to present a case report about ocular Amyloidosis.
Case Illustration: 17 years-old-female complained tumor in both eye since 5 years ago. Visual acuity (VA) and Intraocular Pressure (IOP) for both eye within normal limits. Ocular motility (OCM) within normal limits. Anterior segment examination for the right eye (RE), swelling on inferior palpebra, with solid mass throughout the inferior conjunctival palpebra, defined border, uneven surface, immobile, hyperaemia with size 21x5mm, for the left eye (LE), swelling on superior palpebra, with solid mass, defined border, uneven surface, immobile, hyperaemia with size 12x5mm in 2/3 medial and 10x10mm in 1/3 lateral of the superior conjunctival palpebra. Both tumors were easy to bleed. Funduscopic examination were within normal limits for both eyes. We’ve done our excisional biopsy, and came with Amyloidosis. We consult this patient to Internal department for any systemic manifestation. She got Metatrexate for a month and changed to Myfortic for a month too, but there are no changes on the tumors condition. Internal Department concluded that its more to primary Amylodosis rather than secondary Amyloidosis.
Discussion: The ophthalmic manifestations for Amyloidosis are uncommon, can affect any ocular and periocular structure. Periocular and orbital amyloidosis is a slow-progressing illness. Visible or palpable periocular mass or tissue infiltration, ptosis, are the most common indications and symptoms which matched with our patient condition. Management for ocular amyloidosis may be vary, most studies recommend debulking excision with low recurrence and progression rate.
Conclusion: Although we can suspect Amyloidosis through examination, histopathologic examination is necessary for definite diagnosis. There are no definite management for Amyloidosis, but we can relief patient discomforts depend on the complaint.
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