Development Of Technology and Study of Solubility Of «Fatifiltrum» Capsules
DOI:
https://doi.org/10.52783/jns.v14.3452Keywords:
adsorption, enterosorbent, glauconite, physical and mechanical properties, mathematical planning of the experiment, optimization of the composition, technology, technology «Fatifiltrum» capsules, solubilityAbstract
The article presents the results of experimental studies on the development of the optimal composition of «Fatifiltrum» capsules, formulated based on purified and activated natural glauconite. By analyzing the physical and mechanical properties of purified glauconite and applying experimental design methods—multifactorial plans based on 3×3 Latin squares—the optimal composition of the capsule mass was selected. Additionally, the solubility of «Fatifiltrum» capsules was studied.
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Analiz enterosorbentov, predstavlennix v roznichnom zvene farmatsevticheskogo rinka/G.A. Galkina, Ye.I. Gribkova, M.M. Kurashov, Ye.M. Rasner// Farmatsiya, 2017, t. 66.- №6.- S. 38-42.
Starchenko, V. Enterosorbsionnie texnologii v meditsine / V. Starchenko // Novaya apteka. – 2011. – № 3. – S. 90-91.
Gosudarstvenniy Reyestr. Lekarstvennix sredstv, izdeliy meditsinskogo naznacheniya i meditsinskoy texniki, razreshennix k primeneniyu v meditsinskoy praktike.- Izd. №27, pererabotannoye i dopolnennoye, po sostoyaniyu na 21.12. 2022 g. – Tashkent, 2023.- 1120 s.
Umaraliyeva N.R., Maksudova F.X. Izucheniye strukturno-teksturnix svoystv prirodnogo minerala glaukonita kak perspektivnogo enterosorbenta/ Materiali mejdunarodnoy nauchnoy prakticheskoy konferensii, “Sovremennoye sostoyaniye farmatsevticheseoy otrasli: problemi i perspektivi” (Posvyashayetsya pamyati S.N.Aminova).-Tashkent,2023.-S.68-69.
O‘zbekiston Respublikasi Davlat farmakopeyasi, 2021, 1-nashr, jild 1, qism 1.-1214 b.
Yunusova Kh.M., Jaloliddinova M.Sh. Studying pharmacotechnological aspects and stability of “Ortof-S” tablets // World journal of pharmacy and pharmaceutical sciences.-2019.-Vol.-8.-Issue 1.-P. 277-288.
Groshoviy T.A., Markova Ye.V., Golovkin V.A. Matematicheskoye planirovaniye eksperimenta v farmatsevticheskoy texnologii. Plani dispersionnogo analiza. - Kiyev: Vissh. shk.,1992.-187 s.
GF RF XIII-izdaniya. OFS.1.4.2.0009.15. Odnorodnost massi doziirovannix lekarstvennix form. [Rejim dostupa: https://pharmacopoeia.regmed.ru/pharmacopoeia/izdanie-13/1/1-4/1-4-2/1-4-2-9/odnorodnost-massy-dozirovannykh-lekarstvennykh-form/ Data obrasheniya: 04.04.2025].
Umaraliyeva N.R., Maksudova F.X., G.R.Yusupova. Sravnitelnoye izucheniye texnologicheskix svoystv aktivirovannogo glaukonita i granul «Fatifiltrum»/ Cb. Materalov nauchn.prakt.konf. «Sovremennie dosjenya i perspektivi farmatsevcheskoy texnologii».- Tashkent, 2023. – S.229-230С.
Farmatsevticheskaya texnologiya.Texnologiya lekarstvennix form[Elek tronniy resurs]: uchebnik / I. I. Krasnyuk, G. V. Mixaylova, T. V. Denisova, V. I. Sklyarenko; Pod red. I. I. Krasnyuka, G. V. Mixaylovoy. - M.: GEOTAR-Media, 2015. -http://www.studentlibrary.ru/book/ISBN9785970435274.html
Grady L.T. An early look at dissolution testing, including equipment, calibration, and acceptance criteria // Dissolution Technologies. 2014. Т. 21. № 3. С. 20–23.
Marroum P.J. History and evolution of the dissolution test // Dissolution Technol. 2014. Т. 21. № 3. С. 11–16.
GF RUz "Testi na "rastvorimost" tverdix lekarstvennix form». – Tashkent, 2021.- T. I. - Chast 1. - S. 435.
Izucheniye sorbsii metilenovogo sinego glaukonitom/ Shvidenko I. G., Venig S. B., Chernova R. K., Selifonova Ye. I. i dr.// Izv. Sarat. un-ta. Nov. ser. Ser. Ximiya. Biologiya. Ekologiya. 2018. - T. 18, vip. 1. - S.91-97
The Unired States Pharmacopeial Convention. USP 36 NF-31.2013
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