A Comparative, Cross-Sectional Study On Prevalence Of Sleep Apnea In Chronic Kidney Disease And Heart Failure Patients

Authors

  • Bhavana.R
  • Pallavi Singh

DOI:

https://doi.org/10.52783/jns.v14.3319

Keywords:

Sleep Apnea, Chronic Kidney Disease, Heart Failure, Apnea-Hypopnea Index, Obesity, Fluid Retention, Quality of Life, Polysomnography, Risk Factors, CPAP Therapy

Abstract

Background: Sleep Apnea is often ignored in patients with Chronic Kidney Disease (CKD) and Heart Failure (HF). The factors that cause sleep apnea in these two conditions are obesity, fluid retention, and hypertension. This study will compare the prevalence, risk factors, and effect of sleep apnea on quality of life in patients with CKD and HF.

Methods: A cross-sectional study was conducted with 132 subjects, comprised of 66 CKD and 66 HF patients, in a tertiary hospital. Collected were socio-demographic characteristics, clinical data, and lifestyle data. All patients underwent overnight polysomnography for apnea-hypopnea index (AHI) and sleep efficiency assessments. Quality of life (QoL) was assessed by the SF20 (Short Form-20) Health Survey. Data were analyzed using T-test and chi-square test with a significance level set at p < 0.05.

Results: Sleep apnea was prevalent in 69.70% of CKD and 75.76% of HF patients, with severe cases more frequent in HF (21.21%). Key risk factors included obesity, fluid retention, and male gender. Both groups experienced reduced quality of life, emphasizing the need for early detection and targeted interventions to improve outcomes.

Conclusion: In CKD and HF patients, sleep apnea is highly prevalent and severely affects the quality of life. Patients with HF showed a slightly higher degree of prevalence of sleep apnea. Routine screening and targeted interventions are necessary to prevent the occurence of sleep apnea. Long-term effects and treatment-related responses need to be researched.

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References

Pisano A, Zoccali C, Bolignano D, D'Arrigo G, Mallamaci F. Sleep apnoea syndrome prevalence in chronic kidney disease and end-stage kidney disease patients: a systematic review and meta-analysis. Clin Kidney J. 2023 Nov 14;17(1):sfad179

Maung SC, El Sara A, Chapman C, Cohen D, Cukor D. Sleep disorders and chronic kidney disease. World J Nephrol. 2016 May 6;5(3):224-32.

Pallavi Singh , a review on drug utilization study of hypertensive drugs in outpatient in the department of general medicine of tertiary care hospital. https://www.pnrjournal.com/index.php/home/article/view/8648

Burkhalter DA, Cartellá A, Cozzo D, Ogna A, Forni Ogna V. Obstructive sleep apnea in the hemodialysis population: are clinicians putting existing scientific evidence into practice? Front Nephrol. 2024 Jun 10;4:1394990.

Polecka A, Olszewska N, Danielski Ł, Olszewska E. Association between Obstructive Sleep Apnea and Heart Failure in Adults-A Systematic Review. J Clin Med. 2023 Sep 22;12(19):6139

Donovan LM, Boeder S, Malhotra A, Patel SR. New developments in the use of positive airway pressure for obstructive sleep apnea. J Thorac Dis. 2015 Aug;7(8):1323-42.

Khan YH, Sarriff A, Adnan AS, Khan AH, Mallhi TH. Chronic Kidney Disease, Fluid Overload and Diuretics: A Complicated Triangle. PLoS One. 2016 Jul 21;11(7):e0159335

Drager LF, McEvoy RD, Barbe F, Lorenzi-Filho G, Redline S; INCOSACT Initiative (International Collaboration of Sleep Apnea Cardiovascular Trialists). Sleep Apnea and Cardiovascular Disease: Lessons From Recent Trials and Need for Team Science. Circulation. 2017 Nov 7;136(19):1840-1850.

Singh P, Geetha P. Antidepressants exposure during gestation and their impact on the neurodevelopment and physical outcomes in the off spring. Int J Health Sci (IJHS) [Internet]. 2022 [cited 2025 Mar 21];6(S3):5656–64. Available from: https://sciencescholar.us/journal/index.php/ijhs/article/view/7209

Pallavi Singh, M.Manisha, S.P.Muralidharan,et al. The assessment of insomnia and fatigue in night shift workers https://doi.org/10.37896/HTL27.5/3529

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Published

2025-04-09

How to Cite

1.
Bhavana.R B, Singh P. A Comparative, Cross-Sectional Study On Prevalence Of Sleep Apnea In Chronic Kidney Disease And Heart Failure Patients. J Neonatal Surg [Internet]. 2025Apr.9 [cited 2025Nov.4];14(13S):600-6. Available from: https://jneonatalsurg.com/index.php/jns/article/view/3319