A Retrospective Study on Drug Induced Complications Among Different Age Groups
DOI:
https://doi.org/10.52783/jns.v14.2581Keywords:
Drug induced complications, NSAID’s, hypoglycemia, hypersensitivityAbstract
Aim And Objective: This study is aimed to perform a retrospective study on drug induced complications among different age groups.
Methodology: This retrospective study was conducted at Aware Global Hospital in Hyderabad aimed to investigate the prevalence of drug induced complications among them. Over a 6 months period, data was collected from 85 patient cases from general medicine department.
Results: The research findings reveal a higher drug induced complications incidence in males (54%) than females (46%), predominantly drug induced hypoglycemia (27.05%). According to WHO classification of age groups elderly age group (60-74 years) accounted for maximum DID’s (45.58%). Hypoglycemia (27.05%), hypersensitivity (11.80%), hyponatremia (8.23%), hyperglycemia (8.23%), hepatopathy (7.05%), cough (5%), gastritis (3.52%), AKI (2.4%), parkinsonism (2.4%), pedal edema (2.4%), oral bleed (2.4%) was some of the drug induced complications involved. The 61-70 age group faces a higher risk (31%), often linked to comorbidities.
Conclusion: The study concluded that a total of 85 patients with drug induced complications has been found a peak in the age group 61-70, with a higher incidence in males compared to females. Usage of anti-diabetic agents, anti-hypertensives, antibiotics, corticosteroids, NSAID’s, anti-tubercular agents, anti-coagulants, anti-platelets, anti-psychotics were usually involved in causing complications.
Downloads
Metrics
References
Suma TK. Drug induced diseases. API 2017; 79:435-438.
Chuenjid Kongkaew, Peter R Noyce, and Darren M Ashcroft: Hospital Admissions Associated with Adverse Drug Reactions: A Systematic Review of Prospective Observational Studies; The Annals of Pharmacotherapy 2008 July/August; Volume 42: P.1017-25.
John R Litaker and James P. Wilson: Chapter 2: Epidemiology and Public Health Impact of Drug-Induced Diseases: Section I. Magnitude/Significance of Drug-Induced Diseases: Impact on the Health Care System. Textbook of Drug-Induced Diseases: Prevention, Detection and Management, 2nd Edition (2010). P.22.
Dr. Simi Paknikar, MD: Drug-Induced Diseases; The Medindia Medical 2017.
Mina T. Kelleni and Mahrous Abdelbasset: Chapter 7: Drug Induced Cardiotoxicity: Mechanism, Prevention and Management: Intech Open. Textbook of Cardiotoxicity, 2018 November. P.127-128.
Tammie Lee Demler: Drug-Induced Neurological Conditions; US Pharmacist 2014; 39(1):47-51.
Raissy, Hengameh H., Michelle Harkins. Chapter 15: Drug-Induced Pulmonary Diseases: Joseph T. Dipiro, Robert L. Talbert, Gary C. Yee, Gary R. Matzke, Barbara G. Wells, L. Michael Posey: Pharmacotherapy: A Pathophysiologic Approach, 9th Edition (2014).
Fatemeh Ghane Shahrbaf, Farahnak Assadi: Drug-induced renal disorders: Journal of Renal Injury Prevention, Volume 4, Number 3, September 2015; P.57-60.
H L Philpott, S Nandurkar, J Lubel, P R Gibson: Drug-induced gastrointestinal disorders; Frontline Gastroenterology 2014; Volume5: Issue 1:49-57
Rao KV. Chapter 24: Drug-Induced Hematologic Disorders. In: Dipiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey L.eds. Pharmacotherapy: A Pathophysiologic Approach, 9e New York, NY: McGrawHill, 2014.
Rajesh Ramwani, Puja Khanna Malav, Savita Saini, Chetan Prakash Suman, S.K. Mathur; A Retrospective Cross Sectional Analysis of Drug Induced Diseases in A Tertiary Care Teaching Hospital Western Rajasthan; International Journal of Pharmaceutical and Clinical Research 2023 June; Volume 15; Issue 7; P. 109-113.
Vishal R Tandon, Vijay Khajuria, Vivek Mahajan, Aman Sharma, Zahid Gillani and Annil Mahajan: Drug-induced diseases (DIDs): An experience of a tertiary care teaching hospital from India; Indian J Med Res 2015 July; Volume 142; Issue 1; P.33-41.
Hou Chan Loo, Fairuz Osman, Siew Lee Ho, Sing Yee An, Yim Mei Au Yong, Ee Ming Khoo; Incidence of angiotensin-converting enzyme inhibitor-induced cough in a Malaysian public primary care clinic: A retrospective cohort study; Malays Fam Physician; 2022 March 22nd; Volume17; Issue 1; P.66-70.
Rodolfo Savica, Brandon R. Grossardt, James H. Bower, J. Eric Ahlskog, Michelle M. Mielke, Walter A. Rocca; Incidence and Time Trends of Drug-Induced Parkinsonism A 30-year Population-Based Study; Movement Disorders; 2016 Oct 25th; Volume 32; Issue 2; P. 227-234.
Haim Ben-Ami, Pradeep Nagachandran, Ayelet Mendelson, Yeouda Edoute; Drug-Induced Hypoglycemic Coma in 102 Diabetic Patients; Arch Intern Med; 1999 Feb 8th; Volume 159, Issue 3; P. 281-284.
Rajesh A. Maheshwari, Neha R. Gulati, Prem J. Prajapati, Nikunj P. Vekariya, Harshal Joshi, Rajesh Hadia and Hemraj Singh Rajput; An Observational Prospective Study to Find Out the Incidence of Acute Kidney Injury who are taking Non-Steroidal Anti-inflammatory Drugs; J Young Pharm; 2023 Dec 7th; Volume 15; Issue 4; P. 711-715
Arunava Saha, Margaret Shanthi F. X., Blessed Winston A., Saibal Das, Aniket Kumar, Joy S. Michael, and T. Balamugesh; Prevalence of Hepatotoxicity from Antituberculosis Therapy; A Five-Year Experience from South India; Journal of Primary Care and Community Health; 2016 July; Volume 7; Issue 3; P. 171-174.
Bolin Zhu, Pengfei Jin, Jianchun Li, Yuanchao Zhu; Retrospective Analysis of Risk Factors for Cefoperazone/Sulbactum-Induced Thrombocytopenia in Adult Chinese Patients: A Six-Year Real-World Study; Infection and Drug Resistance 2024; Volume 17; P. 3901-3911.
Downloads
Published
How to Cite
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
Terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.