Prevalence, Interpretation and Management of Diabetic Lower Limb Amputation in A Tertiary Care Centre

Authors

  • J. Sridhar MS
  • Pratheeba P
  • A. P. Subburaaj MS
  • Arun Balaji MS
  • Deepak V

DOI:

https://doi.org/10.52783/jns.v14.1911

Keywords:

diabetes, peripheral vascular disease, diabetic foot ulcer, amputation.

Abstract

Background and Objectives: Diabetic foot ulcers are a common and serious complication of diabetes, leading to significant morbidity and, in severe cases, amputation. These ulcers often result from prolonged hyperglycaemia, poor vascular supply, and neuropathy, necessitating prompt and effective management to prevent adverse outcomes. This study was conducted to investigate the prevalence, predictors, and management of diabetic foot ulcers.

Methods: This prospective hospital-based study was conducted over a two-year period at Vinayaga missions kirupananda variyar medical college,Salem. Patients aged 40-80 with diabetic foot ulcers were included, provided they did not have traumatic, vasculitic, or neoplastic ulcers. After obtaining informed consent and ethical clearance, detailed patient histories were recorded, and relevant investigations including complete blood count, X-rays, fasting and postprandial blood sugar levels, lipid profiles, renal function tests, serum albumin, and pus cultures were performed. Data were analyzed using descriptive statistics, and outcomes were assessed in terms of hospital stay duration and recovery speed.

Results: The study included 100 participants, predominantly aged 51-60 years (38%), with a mean age of 56.67 years. The cohort was 55% male and 45% female. Most participants had diabetes for more than 5 years (65%), and the average HbA1c level was 9.8%. Diabetic foot ulcers were present in 28% of patients. Cultured wound samples predominantly showed Staphylococcus (39.28%), followed by Proteus (21.42%).

Conclusion: This study highlights the significant burden of diabetic foot ulcers in the study population, with most cases occurring in older adults with long-standing diabetes. The findings emphasize the importance of early intervention and comprehensive care to improve outcomes and reduce the risk of amputation.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Pendsey S. New Delhi, India: Jaypee Brothers Medical Publishers; 2003. Diabetic Foot: A Clinical Atlas. [Google Scholar]

Prevalence of diabetic foot ulcers in newly diagnosed diabetes mellitus patients. Sinharay K, Paul UK, Bhattacharyya AK, Pal SK. https://pubmed.ncbi.nlm.nih.gov/23741832/ J Indian Med Assoc. 2012;110:608–611. [PubMed] [Google Scholar]

Pradeepa R, Mohan V. Epidemiology of type 2 diabetes in India. Indian J Ophthalmol. 2021;69:2932–8. [PMC free article] [PubMed] [Google Scholar]

Reed J, Bain S, Kanamarlapudi V. A review of current trends with type 2 diabetes epidemiology, aetiology, pathogenesis, treatments and future perspectives. Diabetes Metab Syndr Obes. 2021;14:3567–602. [PMC free article] [PubMed] [Google Scholar]

Sun H, Saeedi P, Karuranga S, Pinkepank M, Ogurtsova K, Duncan BB, et al. IDF Diabetes Atlas:Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045. Diabetes Res Clin Pract. 2022;183:109119. [PMC free article] [PubMed] [Google Scholar]

Tinajero MG, Malik VS. An update on the epidemiology of type 2 diabetes. Endocrinol Metab Clin North Am. 2021;50:337–55. [PubMed] [Google Scholar]

Grunfeld C. Diabetic foot ulcers:Etiology, treatment, and prevention. Adv Intern Med. 1992;37:103–32. [PubMed] [Google Scholar]

Akhtar S, Latif M, Ahmed OS, Sarwar A, Alina A, Khan MI. Prevalence of foot ulcers in diabetic patients in Punjab, Pakistan. Front Public Health. 2022 Aug 8;10:967733. doi: 10.3389/fpubh.2022.967733. PMID: 36016895; PMCID: PMC9397578.

Đinh, Thanh & Veves, Aristidis. (2015). The influence of gender as a risk factor in diabetic foot ulceration. Wounds : a compendium of clinical research and practice. 20. 127-31.

Daniele T.M.C., Vasconcelos J.P., Coutinho F.G. Self-care assessment of patients with type 2 diabetes in a primary care unit. Cinergis. 2014;15(3):135–139. [Google Scholar] [Ref list]

Almobarak AO, Awadalla H, Osman M, Ahmed MH. Prevalence of diabetic foot ulceration and associated risk factors: an old and still major public health problem in Khartoum, Sudan? Ann Transl Med. 2017 Sep;5(17):340. doi: 10.21037/atm.2017.07.01. PMID: 28936434; PMCID: PMC5599292.

Akyüz S, Bahçecioğlu Mutlu AB, Guven HE, Başak AM, Yilmaz KB. Elevated HbA1c level associated with disease severity and surgical extension in diabetic foot patients. Ulus Travma Acil Cerrahi Derg. 2023 Sep;29(9):1013-1018. doi: 10.14744/tjtes.2023.08939. PMID: 37681727; PMCID: PMC10560815.

Kim J. The pathophysiology of diabetic foot: a narrative review. J Yeungnam Med Sci. 2023;40(4):328-334.

Hamid MH, Arbab AH, Yousef BA. Bacteriological profile and antibiotic susceptibility of diabetic Foot infections at Ribat University hospital; a retrospective study from Sudan. J Diabetes Metab Disord. 2020 Oct 13;19(2):1397-1406. doi: 10.1007/s40200-020-00660-8. PMID: 33553032; PMCID: PMC7843840.

Downloads

Published

2025-03-03

How to Cite

1.
MS JS, P P, MS APS, MS AB, V D. Prevalence, Interpretation and Management of Diabetic Lower Limb Amputation in A Tertiary Care Centre. J Neonatal Surg [Internet]. 2025Mar.3 [cited 2025Nov.3];14(4S):1029-34. Available from: https://jneonatalsurg.com/index.php/jns/article/view/1911