Comparative Study of Propofol and Sevoflurane for Induction of Anesthesia in Day Care Surgery
DOI:
https://doi.org/10.52783/jns.v14.1819Abstract
Propofol and sevoflurane are generally involved sedative specialists in clinical practice, each having unmistakable pharmacokinetic and pharmacodynamic properties. This relative review assesses the viability, wellbeing, hemodynamic strength, recuperation profile, and results of propofol and sevoflurane in everyday sedation. The review depends on an efficient survey of clinical preliminaries and patient information to decide their separate benefits and restrictions. Propofol, an intravenous sedative, is known for its fast beginning, smooth acceptance, and speedy recuperation. It offers brilliant command over sedation profundity yet is related with portion subordinate hypotension and respiratory wretchedness.
Aim: In the context of general anaesthesia, the purpose of this research is to evaluate and contrast the effectiveness, safety, haemodynamic stability, recovery profile, and postoperative outcomes of propofol and sevoflurane in order to learn about the benefits and disadvantages of each of these procedures.
Materials and Methods:For the purpose of determining the pharmacokinetic and pharmacodynamic features of propofol, an intravenous anaesthetic, and sevoflurane, an inhalational anaesthetic, a comprehensive assessment of clinical studies and patient data was carried out. Analyses were performed on a number of parameters, including induction time, depth control, haemodynamic stability, recovery length, and postoperative problems.
Results and Conclusion: As a result of its fast start, smooth induction, and rapid recovery, propofol is an excellent choice for treatments that are scheduled to last for a short period of time. On the other hand, it has been linked to dose-dependent hypotension as well as pneumonia and respiratory depression. In spite of the fact that sevoflurane is associated with postoperative nausea and delayed emergence, it is recognised for its non-irritating qualities, which make it easier to induce smooth induction and maintain haemodynamic stability. When it comes to paediatric anaesthesia and situations that need lengthy maintenance, sevoflurane is more advantageous than propofol. Propofol is preferred for treatments that require quick recovery. In order to achieve optimal perioperative results, the selection of these drugs need to be determined by the patient's health, the requirements of the surgical procedure, and the objectives of the anaesthetic. It is advised that more study be conducted to investigate the use of both of them together for improved anaesthesia management.
Downloads
Metrics
References
Leslie K, Sessler DI, Bjorksten AR, Ozaki M, Matsukawa T, Schroeder M, et al. Propofol causes a dose-dependent decrease in the thermoregulatory threshold for vasoconstriction but has little effect on sweating. Anesthesiology. 1994;81(2):353–60.
Lenhardt R. The effect of anesthesia on body temperature control. Front Biosci (Schol Ed). 2010;2(3):1145–54.
Kurz A, Go JC, Sessler DI, Kaer K, Larson MD, Bjorksten AR. Alfentanil slightly increases the sweatingthreshold and markedly reduces the vasoconstriction and shivering thresholds. Anesthesiology. 1995;83(2):293–9.
Chowdhury T, Prabhakar H, Bharati SJ, Goyal K, Dube SK, Singh GP. Comparisonof propofol versus sevoflurane on thermoregulation in patients undergoingtranssphenoidal pituitary surgery: A preliminary study. Saudi J Anaesth. 2012;6(1):12–5.
Belani K, Sessler DI, Sessler AM, Schroeder M, Mcguire J, Merrifield B, et al. Leg heat content continues to decrease during the core temperature plateau in humans anesthetized with isoflurane. Anesthesiology. 1993;78(5):856–63.
Ikeda T, Sessler DI, Kikura M, Kazama T, Ikeda K, Sato S. Less corehypothermia when anesthesia is induced with inhaled sevoflurane than withintravenous propofol. Anesth Analg. 1999;88(4):921–4.
Matsukawa T, Sessler DI, Sessler AM, Schroeder M, Ozaki M, Kurz A, et al. Heat flow and distribution during induction of general anesthesia. Anesthesiology. 1995;82(3):662–73.
Ozaki M, Sessler DI, Matsukawa T, Ozaki K, Atarashi K, Negishi C, et al. The threshold for thermoregulatory vasoconstriction during nitrousoxide/sevoflurane anesthesia is reduced in the elderly. Anesth Analg. 1997;84:1029–33.
Bentley GN, Gent JP, Goodchild CS. Vascular effects of propofol: smooth muscle relaxation in isolated veins and arteries. J Pharm Pharmacol. 1989;41:797–805.
Robinson BJ, Ebert TJ, O’Brien TJ, Colinco MD, Muzi M. Mechanisms whereby propofol mediates peripheral vasodilation in humans. Sympathoinhibition or direct vascular relaxation? Anesthesiology. 1997;86(1):64–72.
Ronald D. Miller. Intravenous AnestheticsJaapVuyk, ElskeSitsen, and MarijeReekers: 2020: 6 (1, 2), 7452.
Sahinovic MM, Struys MMRF, Absalom AR. Clinical Pharmacokinetics and Pharmacodynamics of Propofol. ClinPharmacokinet. 2018; 57(12):1539-1558.
Clinical comparison of “single agent” anaesthesia with sevoflurane versus target controlled infusion of propofol: K.R. Watson and M.V. Shaw: BJA: 2000; 85/4/541-546
Ghatge S, Lee J, Smith I. Sevoflurane: an ideal agent for adult day-case anesthesia? ActaAnaesthesiol Scand. 2003 Sep;47(8):917-31.
Kulkarni S, Harsoor SS, Chandrasekar M, et al. Consensus statement on anaesthesia for day care surgeries. Indian J Anaesth. 2017;61(2):110-124.
Delgado-Herrera L, Ostroff RD, Rogers SA. Sevoflurance: approaching the ideal inhalational anesthetic. a pharmacologic, pharmacoeconomic, and clinical review. CNS Drug Rev. 2001;7(1):48-120.
Ghatge S, Lee J, Smith I. Sevoflurane: an ideal agent for adult day-case anesthesia? ActaAnaesthesiol Scand. 2003 Sep;47(8):917-31.
Ebert TJ, Muzi M, Lopatka CW. Neurocirculatory responses to sevoflurane in humans. A comparison to desflurane. Anesthesiology. 1995;83(1):88–95.
Kulkarni S, Harsoor SS, Chandrasekar M, et al. Consensus statement on anaesthesia for day care surgeries. Indian J Anaesth. 2017;61(2):110-124.
Guidelines for Ambulatory Anesthesia (Approved by the ASA House of Delegates on October 15, 2003, last amended on October 22, 2008, and reaffirmed on October 17, 2018)
.Bangera A. Anaesthesia for adenotonsillectomy: An update. Indian J Anaesth. 2017; 61(2):103-109.
Hoddeson, E. K. and Gourin, C. G: Adult tonsillectomy: Current indications and outcomes’, Otolaryngology–Head and Neck Surgery, 2009:140(1), pp. 19– 22.
. Wong HT, Sien Hui T, Chong AW. Is Daycare Tonsillectomy Safe?. Iran J Otorhinolaryngol. 2016;28(86):183-188.
Intravenous or inhaled induction of anaesthesia in adults? An audit of preoperative patient preferences: Anton A van den Berg FRCA, Dudley A. Chitty, MD, Ramoun D. Jones, MD, Mir S. Sohel, MD and Ali Shahen MD : Anaesthesia & analgesia: 2005; 100:1422-1424.
A. Thwaites S. Edmends and I. Smith : Inhalation induction with sevoflurane: a double blind comparison with propofol: BJA, 1997; Issue 4: 356-361.
Brian Fredman. Michael H. Nathanson, Ian Smith, Junkewang, Kevin Klein,and Paul F. White:Sevoflurane for outpatient anesthesia: A comparison with propofol: Anesthesia& Analgesia: 1995;81:823-8.
W. Scott Jellish, Cynthia A Lien, H.Jerrel Fontenot, and Richard Hall, . :The comparative effects of sevoflurane versus propofol in the induction and maintenance of anaesthesia in adult patients:– Anesthesia& Analgesia: 1996: 82, 479 -485
J. K. Moore, E.W. Moore, R.A. Elliott, A.S.St. Leger, K. Payne and J. Kerr Propofol and halothane versus sevoflurane in paediatric day - case surgery: induction and recovery characteristics:: BJA: 2003; 461-466.
Bharti N, Chari P, Kumar P. Effect of sevoflurane versus propofol-based anesthesia on the hemodynamic response and recovery characteristics in patients undergoing microlaryngeal surgery. Saudi J Anaesth. 2012;6(4):380- 384.
Husedzinović I, Tonković D, Barisin S, Bradić N, Gasparović S. Hemodynamic differences in sevoflurane versus propofolanesthesia. CollAntropol. 2003 Jun;27(1):205-12.
J, Gupta. A, Pedersen. F.M, :Recovery characteristics of sevoflurane or propofol based anaesthesia for day - care surgery: ReaderActaanaesthesiologica Scandinavia: 1997; 41: 988-984.
Hanna Viitanen, PekkaTarkkila, Susanna Mennander. MattiViltanen, PaiviAnnila, : sevoflurane - maintained anaesthesia induced with propofol or sevoflurane in small children: induction and recovery characteristics - Canadian Journal of Anaesthesia, 1999/46:1/ pp 21-28.
Picard, L. Dumont and M. Pellegrini : Quality of recovery in children: Sevoflurane versus propofol: VActaAnaesthesiologica Scandinavia 2000; 44: 307- 310.
.Joo HS, Perks WJ. Sevoflurane versus propofol for anesthetic induction: a meta- analysis. AnesthAnalg. 2000 Jul;91(1):213-9.
Sahar M. Siddik - Sayyid, Marie T. Aouad, Samar K. Taha,Dima G. Daaboul, Patricia G. Deeb. Faraj M. Massouh. Marie Rose A. Muallem. and Anis S. Baraka. A comparison of sevoflurane - propofol versus sevoflurane or propofol for Laryngeal mask airway insertion in adults:: Anesthesia& Analgesia: 2005; 100: 1204-09.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
Terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
