Cadaveric study of the origin, course, branching pattern, and termination of the left coronary artery in Indian population: An observational study
Keywords:
Anomalies, Coronary arteries, Heart vessels, Left coronary artery, left descending artery, left circumflex arteryAbstract
Background: The heart functions as a vital organ by pumping blood to all body tissues through the aorta. Its muscular wall (myocardium) receives oxygen and nutrients from the coronary arteries, which are divided into right and left coronary arteries.
Methods: A total of 50 adult human heart specimens were included in the study. The specimens were obtained from deceased individuals subjected to routine cadaveric dissection for undergraduate (MBBS) teaching purposes in the Department of Anatomy, Index Medical College Hospital & Research Centre (IMCH & RC), Indore. We proceeded to investigate the branching pattern of the LCA. Throughout their whole course, from the point of origin to the point of termination of LCA was tracked. The branching of LCA was observed till their termination. Any variation in the course and branching pattern was recorded and photographed.
Results: The left coronary artery most commonly originated from the left posterior aortic sinus (98%) which is the most common pattern, with only a rare origin from the anterior aortic sinus (2%). Regarding branching pattern, bifurcation was the predominant type (82%), followed by trifurcation (14%), while single and quadrifurcation patterns were uncommon (2% each).
Conclusions: the present study focuses on elucidating these variations to aid in accurate diagnosis and effective therapeutic management of coronary artery disease
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References
[1] Standring S. Gray’s Anatomy. The Anatomical Basis of clinical Practice. 40th Ed. New York: Chrchill Livingstone;2008:995-1027.
[2] Bhat R, Shanbhag P. Knowledge, Attitude, and Practice Study on Cardiovascular Disease Risk Factors in the Mangalore Community. Oral Sphere J. Dent. Health Sci. 2025;1(1):19-28. doi: 10.63150/osjdhs.2025.32
[3] Brothers JA, Frommelt MA, Jaquiss RD, Myerburg RJ, Fraser Jr CD, Tweddell JS. Expert consensus guidelines: anomalous aortic origin of a coronary artery. The Journal of thoracic and cardiovascular surgery. 2017 Jun 1;153(6):1440-57.
[4] Mawson JB. Congenital heart defects and coronary anatomy. Texas Heart Institute Journal. 2002;29(4):279.
[5] Gupta T, Saini A, Sahni D. Details of the origin, course, branching patterns, termination and variations of the left coronary artery–a cadaveric study. Eur. J. Anat. 2016 Apr 1;20(2):151-8.
[6] Lakshmiprabha S, Afroze KH, Ramesh P, Asha KR, Shivaleela C, Anupama D. Variations in the anatomical and branching pattern of the left coronary artery: a cadaveric study. Int J Res Med Sci. 2018 Apr; 6(4):1235-40.
[7] Beg MR, Singh A, Goel S, Goel AK, Goel V, Goyal P, Surana A, Singh NK, Dhanda MS. Anatomical variations of coronary artery and frequency of median artery: A cadaveric study from Northern India. Int Arch Integr Med. 2015;2(5):88-91.
[8] Ravi V, Tejesh S. Anatomical variation in branching pattern and dominance in coronary arteries: A cadaveric study. Int J Anat Res. 2017;5(1):3611-17
[9] Baptista CA, DiDio LJ, Prates JC. Types of division of the left coronary artery and the ramus diagonalis of the human heart. Japan Heart J. 1991; 32(3):323- 35.
[10] Ballesteros LE, Ramirez LM. Morphological expression of the left coronary artery: a direct anatomical study. Folia Morphologica. 2008;67(2):135-42.
[11] Ogeng’o JA, Misiani MK, Olabu BA, Waisiko BM, Murunga A. Variant termination of the left coronary artery: Pentafurcation is not uncommon. Eur J Anat. 2014;18(2):98-101.
[12] Udhayakumar S, Yasawardene SG. A preliminary study on anatomy of the main trunk of left coronary artery of Sri Lankans. Proc Jaffina Univ Int Res Conf. 2012;3:1327-30.
[13] Patel JP, Desai JN, Bhojak NR. A cadaveric study of variation in branching pattern of left coronary artery. J Anat Soci Ind. 2016;65(2):101-3.
[14] Surucu HS, Karahan ST, Tanyeli E. Branching pattern of the left coronary artery and an important branch. The median artery. Saudi Med J. 2004;25(2):177-81.
[15] Kalpana R. A study on principal branches of coronary arteries in humans. J Anat Soc Ind. 2003;52(2):137-40.
[16] Mallashetty N, Itagi V. The study of branching pattern and variations in the left coronary artery in human heart with a unique case of crossing of coronary arteries- A cadaveric study. Ind J Clin Anatomy Physiol. 2017;4(1):48-50.
[17] Siri AM. Study of branching pattern and distribution of coronary arteries in adult human heart (Doctoral dissertation, RGUHS), 2008.
[18] Das H, Das G, Das DC, Talukdar K. A study of coronary dominance in the population of Assam. J Anat Soc Ind. 2010;59 (2):187-91.
[19] Anbumani TL, Christus D, Selvi TA. An anatomical study on the coronary arteries and their variations. Int J Anat Res. 2016;4(1):2114
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