Ayurvedic Management Of Hepatorenal Syndrome: A Case Study
DOI:
https://doi.org/10.63682/jns.v14i32S.9755Keywords:
Hepatorenal syndrome (HRS), Nithya Virechana, Basti, Ekanga Lepa, ShamanoushadhisAbstract
Introduction: Hepatorenal Syndrome (HRS) is a serious complication of advanced liver disease characterized by functional renal failure without any structural kidney damage, typically occurring in patients with cirrhosis, severe liver failure or fulminant hepatic failure and marked by renal vasoconstriction and reduced renal perfusion. This article emphasizes the successful case study of Hepatorenal Syndrome which was treated at our hospital in a comprehensive manner both locally and systemically by utilizing the principles of Ayurveda in reducing the symptoms and thereby improving quality of the subject.
Methodology : A 48 year old male patient diagnosed with Hepatorenal syndrome, presenting with complaints of Massive Ascites, Swelling in both lower limbs, reduced urine output, reduced appetite, reduced sleep, Generalized weakness and itching all over the body with elevated creatinine and bilirubin levels and low Haemoglobin count was administered with comprehensive Ayurvedic management which included Nithya Virechana, Ekanga Lepa over Abdomen, Basti and Shamanoushadhis followed by Pathya Ahara Sevana.
Result : Marked improvements were observed in the patient's subjective symptoms, along with a reduction in creatinine and bilirubin levels and an increase in haemoglobin count.
Discussion: By utilizing the principles of Ayurveda case of Hepatorenal syndrome was successfully managed at our hospital. The combined effect of external therapies and Shamanoushadhis facilitated effective liver detoxification, reduced fluid accumulation, improved appetite and sleep, alleviated generalized weakness, and significantly enhanced the patient’s overall well-being, thereby contributing to a better quality of life
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References
1.Longo D L, Fauci A S, Kasper D L, Hauser S L, Jameson J L, Loscalzo Joseph, editors. Harrison’s Principles of Internal Medicine. Vol.2 Ch.308. 18th ed. Cirrhosis and its complications, published by The McGraw-Hill Companies; 2012. pp. 2601
2. Ginès A, Escorsell A, Ginès P, Saló J, Jiménez W, Inglada L, Navasa M, Clària J, Rimola A, Arroyo V, et al. Incidence, predictive factors, and prognosis of the hepatorenal syndrome in cirrhosis with ascites. Gastroenterology. 1993;105(1):229–36.
3. Borle A, Kanitkar S, Bagare PC, Ahlawat M, Ande SP. A study of the clinical profiles of patients with hepatorenal syndrome. Cureus. 2024 Aug 13;16(8):e66778. doi: 10.7759/cureus.66778.
4.Vaidya Jadavji Trikamji Acharya ed., Charaka Samhita (ISBN : 978-93-81608-55-5) of Agnivesha, Chakrapanidatta and Dridhabala’s Ayurveda Dipika (sans), Reprinted ed., Chikitsa Udara Chikitsitam, 13/61, Chaukhamba Orientalia, Varanasi, 2022, pp.495
5. Mohan H. The liver, biliary tract and exocrine pancreas. In: Mohan H, editor. Textbook of Pathology: With Pathology Quick Review and MCQs. 6th ed. New Delhi: Jaypee Brothers Medical Publishers; 2010. p. 577–635.
6. Govinda Dasji S; Shastry AK, commentator; Lochan K, translator. Bhaishajya Ratnavali. Vol. 2. Varanasi: Chaukhamba Publications; Chapter 40, Udara Roga, Shloka 67–68. p.579. ISBN 81-86937-93-5.
7. Vāgbhaṭa. Aṣṭāṅga Hṛdaya, Kalpa–Siddhi Sthāna, Chapter 2: Virechana Kalpa Adhyāya. In: Arunadatta, Sarvāṅgasundarā; Hemadri, Āyurvedarasāyana, commentators. Varanasi: Chaukhamba Publications; p. 742. Shloka 9. ISBN: 978-81-7637-017-2.
8. Govinda Dasji S; Shastry AK, commentator; Lochan K, translator. Bhaishajya Ratnavali. Vol. 2. Varanasi: Chaukhamba Publications; Chapter 42, Shotha Roga, Shloka 27. p.648. ISBN 81-86937-93-5.
9. Prof. K.R.Shrikantha Murthy. Sharangadhar Samhita, Madhyama Khanda, 7th chapter, 84-87th verse, Varanasi: Chaukhambha Orientalia; 2010. p. 109.
10. Patel MV, Gupta SN, Patel NG. Effects of Ayurvedic treatment on 100 patients of chronic renal failure (other than diabetic nephropathy). Ayu. 2011 Oct;32(4):483-6. doi: 10.4103/0974-8520.96120. PMID: 22661841; PMCID: PMC3361922.
11. Reddy KRC. Text book of Rasa Śāstra. Chapter 9, Auṣadhi Yoga Jñānam; Ārogyavardhinī Guṭikā. Varanasi: Chaukhambha Sanskrit Bhawan; p. 155.
12. Chaudhary M, Goyal M, Mehta C, Harisha CR. Pharmacognostical and pharmaceutical analysis of Katuki Vati – an Ayurvedic formulation for NAFLD. World J Pharm Res. 2025;14(1):873–879. doi:10.20959/wjpr20251-35081.
13. Govinda Dasji S; Shastry AK, commentator; Lochan K, translator. Bhaishajya Ratnavali. Vol. 2. Varanasi: Chaukhamba Publications; Chapter 40, Udara Roga, Shloka 34-35. p.571. ISBN 81-86937-93-5.
14. Vāgbhaṭa. Aṣṭāṅga Hṛdaya, Chikitsa Sthāna, Chapter 19: Virechana Kalpa Adhyāya. In: Arunadatta, Sarvāṅgasundarā; Hemadri, Āyurvedarasāyana, commentators. Varanasi: Chaukhamba Publications; p. . Shloka 28-30. ISBN: 978-81-7637-017-2.
15. Sharma PV, editor and translator. Chakradatta. Chapter 39, Shotha Chikitsa; Shloka 47–50. Varanasi: Chaukhambha Publications; p. 334–335. ISBN: 81-89469-10-X.
16. Madiphala Rasayanam: Uses, Dose, Ingredients, Side effects [Internet]. Ayurmed Info; 2016 Jun 17 [cited 2025 Dec 15]. Available from: https://ayurmedinfo.com/2016/06/17/madiphala-rasayanam-uses-dose-ingredients-side-effects/
17. Govinda Dasa Sen. Bhaishajyaratnavali. Visarpa Rogadhikara, Adhyaya 16, Shloka 16. In: Mishra SN, editor. Bhaishajyaratnavali with Siddhiprada Hindi commentary. Reprint ed. Varanasi: Chaukhambha Surbharati Prakashan; 2014. p. 362.
18. Vasudevan Nampoothiri MR, Mahadevan L, Jayadeep S. Principles and practice of vasti. 2nd ed. Derisanamcope, Kanyakumari District (TN): Sarada Mahadeva Iyer Ayurvedic Educational & Charitable Trust; 2024.
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