Assessing the Prevalence of Maxillary Midline Diastema in Dental College Students: A Cross-Sectional Study
DOI:
https://doi.org/10.63682/jns.v13i1.9548Keywords:
Maxillary Midline Diastema, Prevalence, Dental Students, Labial Frenum, Etiology, Cross-Sectional StudyAbstract
Objective: This study aimed to determine the prevalence, size distribution, and associated etiological factors of maxillary midline diastema (MMD) among dental college students in Bangladesh.
Methods: A multicentre, cross-sectional study was conducted from January 2021 to December 2023, involving 1,407 undergraduate dental students from three institutions. Participants were selected via multistage sampling. Data were collected through clinical examinations performed by calibrated examiners and a structured questionnaire. MMD was defined as a space ≥ 0.5 mm between the maxillary central incisors. Results: The overall prevalence of MMD was 22.2% (n=312). Among those with a diastema, the most common size was 1–2 mm (45.5%), followed by <1 mm (40.1%), and >2 mm (14.4%). No statistically significant associations were found between the presence of MMD and gender (p=0.71) or age (p=0.95). The most prevalent etiological factor was labial frenum abnormality (35.9%), followed by tongue thrusting (29.5%) and tooth size-jaw size discrepancies (24.0%). Other contributing factors included lip biting (20.2%) and thumb sucking (18.6%). Notably, 30.4% of affected students had no identifiable oral habit.
Conclusion: The study reveals a high prevalence of maxillary midline diastema in this young adult population, affirming its status as a common clinical finding. The etiology is predominantly multifactorial, with labial frenum abnormality being the most significant associated factor. The persistence of MMD into early adulthood, particularly among future dental professionals, underscores its relevance as a condition of aesthetic and functional concern. These findings highlight the need for a comprehensive diagnostic approach and effective management strategies in clinical practice and dental education
Downloads
References
Hasan, H. S., Al Azzawi, A. M., & Kolemen, A. (2020). Pattern of distribution and etiologies of Midline diastema among Kurdistan-region Population. Journal of clinical and experimental dentistry, 12(10), e938.
Muhsin, Z. W., & Jasim, A. P. E. S. (2023). The Timing of Orthodontic Treatment.
Marques, L. S., Ramos-Jorge, M. L., Paiva, S. M., & Pordeus, I. A. (2006). Malocclusion: esthetic impact and quality of life among Brazilian schoolchildren. American journal of orthodontics and dentofacial orthopedics, 129(3), 424-427.
Brook, A. H. (2009). Multilevel complex interactions between genetic, epigenetic and environmental factors in the aetiology of anomalies of dental development. Archives of oral biology, 54, S3-S17.
Madi, M., Alamri, A., Aleisa, D., Almusallam, M. O., AlQahtani, S. S., Al-Aql, Z. S., & Alagl, A. S. (2024). Associations between maxillary labial frenum Morphology, Attachment, and Patient-Related clinical factors in Saudi Arabian Adults: Cross-sectional study. The Saudi Dental Journal, 36(4), 615-620.
Valappil, S. M. (2019). Assessment of Bolton’s Tooth Size Discrepancies Among Various Malocclusion Groups and Analysis of Gender Variation in South Indian Population-A Retrospective Study (Master's thesis, Rajiv Gandhi University of Health Sciences (India)).
Gass, J. R., Valiathan, M., Tiwari, H. K., Hans, M. G., & Elston, R. C. (2003). Familial correlations and heritability of maxillary midline diastema. American journal of orthodontics and dentofacial orthopedics, 123(1), 35-39.
Zou, M., Wang, S., Chen, A., Liu, Z., Young, C. A., Zhang, Y., ... & Zheng, D. (2020). Prevalence of myopic macular degeneration worldwide: a systematic review and meta-analysis. British Journal of Ophthalmology, 104(12), 1748-1754.
Kurt, E., Metintas, S., Basyigit, I., Bulut, I., Coskun, E., Dabak, S., ... & PARFAIT Study of Turkish Thoracic Society Asthma‐Allergy Working Group. (2007). Prevalence and risk factors of allergies in Turkey: results of a multicentric cross‐sectional study in children. Pediatric allergy and immunology, 18(7), 566-574.
Hussein, I. F., Kareem, M. I. A., Ahmed, M. J., & Abd Al-Badri, H. J. Psychosocial presentation of Iraqi adolescents attending mental health unit.
Ali, A. P., Mohammadnezhad, M., May, W., & Kabir, R. (2021). The perception of undergraduate dental students toward a clinical learning environment at school of dentistry and Oral Health, Fiji National University, Fiji. Journal of International Society of Preventive and Community Dentistry, 11(1), 26-32.
Salari, N., Darvishi, N., Ahmadipanah, M., Shohaimi, S., & Mohammadi, M. (2022). Global prevalence of falls in the older adults: a comprehensive systematic review and meta-analysis. Journal of orthopaedic surgery and research, 17(1), 334.
Tamay, Z., Akçay, A., Ergin, A., & Güler, N. (2014). Prevalence of allergic rhinitis and risk factors in 6-to 7-yearold children in Istanbul, Turkey. The Turkish journal of pediatrics, 56(1), 31-40.
Choi, S. E., White, J., Mertz, E., & Normand, S. L. (2023). Analysis of race and ethnicity, socioeconomic factors, and tooth decay among US children. JAMA Network Open, 6(6), e2318425-e2318425.
Scott, G. R., & Irish, J. D. (Eds.). (2013). Anthropological perspectives on tooth morphology: Genetics, evolution, variation (Vol. 66). Cambridge University Press.
Li, S., Zhang, X., Cai, Y., Zheng, L., Pang, H., & Lou, L. (2023). Sex difference in incidence of major depressive disorder: an analysis from the Global Burden of Disease Study 2019. Annals of General Psychiatry, 22(1), 53.
Sękowska, A., & Chałas, R. (2017). Diastema size and type of upper lip midline frenulum attachment. Folia morphologica, 76(3), 501-505.
Tadros, S., Ben-Dov, T., Cathain, E. O., Anglin, C., & April, M. M. (2022). Association between superior labial frenum and maxillary midline diastema-a systematic review. Int J Pediatr Otorhinolaryngol, 156(111063), 10-1016.
Jindal, V., Kaur, R., Goel, A., Mahajan, A., Mahajan, N., & Mahajan, A. (2016). Variations in the frenal morphology in the diverse population: A clinical study. Journal of Indian Society of Periodontology, 20(3), 320-323.
Jalaly, T., Ahrari, F., & Amini, F. (2009). Effect of tongue thrust swallowing on position of anterior teeth. Journal of dental research, dental clinics, dental prospects, 3(3), 73.
Abd Rahman, A. N. A., Othman, S. A., & Marya, A. (2023). Measuring tooth size discrepancies using Bolton analysis: a comparative cross-sectional study among major ethnicity in Malaysia. BMC oral health, 23(1), 534.
Gyra, G. G., Kumar, V. S., & Janakiram, C. (2025). Prevalence of Oral Deleterious Habits among children: A systematic review and meta-analysis. Journal of Oral Biology and Craniofacial Research, 15(6), 1539-1562.
Sasaki, K. (Ed.). (2012). Interface Oral Health Science 2011: Proceedings of the 4th International Symposium for Interface Oral Health Science. Springer Science & Business Media
Downloads
Published
How to Cite
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
Terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.