Evaluation of Renal Parenchymal Stiffness in Chronic Kidney Disease Using Shear Wave Elastography

Authors

  • A V V Satya Divakar
  • Jenikar Paulraj
  • Sachin Virmani
  • Likitha Yadlapalli

Keywords:

Chronic kidney disease, Shear Wave Elastography, Ultrasound, diabetic nephropathy, glomerular filtration

Abstract

Background: Chronic kidney disease (CKD) is a public health burden worldwide. Conventional imaging does not measure renal stiffness or fibrosis accurately. Shear wave elastography (SWE) is an ultrasound-based non-invasive technique of tissue stiffness measurement that can potentially enhance CKD staging.


Purpose: To assess the value of SWE in the measurement of renal parenchymal stiffness in CKD patients and compare it with traditional ultrasound..

Downloads

Download data is not yet available.

References

Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int Suppl. 2013;3(1):1–150.

Harambat J, van Stralen KJ, Kim JJ, Tizard EJ. Epidemiology of chronic kidney disease in children. Pediatr Nephrol. 2012;27(3):363–73.

Tuttle KR, Bakris GL, Bilous RW, Chiang JL, de Boer IH, Goldstein-Fuchs J, et al. Diabetic kidney disease: a report from an ADA Consensus Conference. Am J Kidney Dis. 2014;64(4):510–33.

Stevens PE, Levin A; Kidney Disease: Improving Global Outcomes Chronic Kidney Disease Guideline Development Work Group Members. Evaluation and management of chronic kidney disease: synopsis of the KDIGO 2012 clinical practice guideline. Ann Intern Med. 2013;158(11):825–30.

Cosgrove D, Piscaglia F, Bamber J, Bojunga J, Correas JM, Gilja OH, et al. EFSUMB guidelines and recommendations on the clinical use of ultrasound elastography. Part 2: Clinical applications. Ultraschall Med. 2013;34(3):238–53.

Ophir J, Cespedes I, Ponnekanti H, Yazdi Y, Li X. Elastography: A quantitative method for imaging the elasticity of biological tissues. Ultrasound Med Biol. 1991;18(3):283–92.

Vivante A, Hildebrandt F. Exploring the genetic basis of early-onset chronic kidney disease. Nat Rev Nephrol. 2016;12(3):133–46.

Barr RG, Zhang Z, Shear-Wave Elastography of the Kidney: Imaging for Renal Fibrosis? Semin Ultrasound CT MR. 2020;41(5):453–61.

Onur MR, Poyraz AK, Bozgeyik Z, Firdolas F, Orhan I. Shear-wave elastography of the kidneys: Normal values and variability in healthy volunteers. Ultrasound Med Biol. 2015;41(4):960–6.

Guo LH, Xu HX, Fu HJ, Peng A, Zhang YF, Liu LN. Acoustic radiation force impulse imaging for noninvasive evaluation of renal parenchyma elasticity: Preliminary findings. PLoS One. 2013;8(7):e68925.

Goya C, Hamidi C, Ece A, Koca G, Yavuz A, Cetincakmak MG, et al. Acoustic radiation force impulse (ARFI) elastography for detection of renal damage in children. J Med Ultrason. 2015;42(3):403–9.

Cui G, Yang Z, Zhang W, Wang K, Li L, Su L, et al. Evaluation of acoustic radiation force impulse imaging for the renal parenchyma in patients with chronic kidney disease. PLoS One. 2013;8(7):e68925.

Makita Y, Fukuda S, Tsuji Y, Ishii T, Maeda I, Fukuda K, et al. Evaluation of renal shear wave elastography for non-invasive diagnosis of renal fibrosis in patients with chronic kidney disease. Kidney Int Rep. 2020;5(11):1923–31.

Hassan K, Loberant N, Abbas N, Fadi H, Abassi Z. Shear wave elastography imaging for assessing renal fibrosis in diabetic kidney disease: A pilot study. Int J Nephrol Renovasc Dis.2017;10:209–14.

Wang L, Xia P, Lv K, Han J, Dai Q. Acoustic radiation force impulse elastography for non-invasive assessment of renal histopathology in chronic kidney disease. Ultrasound Med Biol. 2014;40(12):2757–65.

Asano K, Ogata A, Tanaka K, Ito J, Ando T, Takata T, et al. Acoustic radiation force impulse elastography of the kidney in chronic kidney disease: Correlation with renal function and histology. Int J Urol. 2014;21(7):686–92.

Dilmen G, Goya C, Arslan S, Ece A, Kantarci M. Diagnostic value of acoustic radiation force impulse elastography for differentiation of obstructive and non-obstructive hydronephrosis in children. Br J Radiol. 2015;88(1054):20140521.

Tan S, Lee YH, Tan PH, Teo M, Teo H, Venkatesh SK. Real-time elastography in the characterization of renal tumours. Clin Radiol. 2013;68(6):e307–14.

Downloads

Published

2025-11-04

How to Cite

1.
Divakar AVVS, Paulraj J, Virmani S, Yadlapalli L. Evaluation of Renal Parenchymal Stiffness in Chronic Kidney Disease Using Shear Wave Elastography. J Neonatal Surg [Internet]. 2025 Nov. 4 [cited 2026 Apr. 14];14(32S):9316-24. Available from: https://jneonatalsurg.com/index.php/jns/article/view/9480