The Efficacy of Honey Compared to Silver Sulfadiazine in Pediatric Burn Wound Dressing in Superficial and Partial Thickness Burns

Authors

  • Lubna Mahek
  • Afzaal Bashir
  • Zubair Shoukat
  • Faryal Iqbal
  • Nabila Talat

Keywords:

Burns, Children, Dressing, Honey, Pain, Silver sulfadiazine, Wound healing

Abstract

Background: Children often get burn injuries, with partial-thickness and superficial burns being the most common kind. Timely and effective wound management is essential to reduce complications, accelerate healing, and minimize scarring.

Objectives: To compare the efficacy of honey versus silver sulfadiazine in dressing superficial and partial-thickness burns in pediatric patients.

Study Design & Setting: This was a comparative interventional study conducted at the Paediatric surgery unit 1 the Children Hospital and University of Child Health Sciences Lahore from Feb 2024 to July 2024.

Methodology: Children with burns that were either superficial or partial-thickness and involving less than 20% TBSA were divided into two equal groups. The patients' ages ranged from 1 to 12 years. Honey dressings were given to Group A, while 1% silver sulfadiazine dressings were given to Group B. Time to wound healing, discomfort during dressing changes, infection rates, and dressing changes were all factors that were evaluated in this study. The data were examined with SPSS version 25, and a significance level of p < 0.05 was deemed.

Results: The honey group showed significantly faster wound healing (9.3 ± 2.1 vs. 13.7 ± 3.4 days; p < 0.001), lower pain scores, reduced infection rates (8.3% vs. 23.3%; p = 0.026), and fewer dressing changes compared to the SSD group.


Conclusion: Compared to silver sulfadiazine, honey is superior for treating children's superficial and partial-thickness burns. It offers faster healing, better comfort, and reduced infection risk, making it a suitable alternative in pediatric burn care

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References

Jordan KC, Di Gennaro JL, von Saint André-von Arnim A, Stewart BT. Global trends in pediatric burn injuries and care capacity from the World Health Organization Global Burn Registry. Frontiers in pediatrics. 2022 Jul 19;10:954995.

Yelvington M, Whitehead C, Turgeon L. Special considerations for pediatric burn injuries. Physical Medicine and Rehabilitation Clinics. 2023 Nov 1;34(4):825-37.

Reddy RK, Murari A, Ali A, Kumar R, Lutunaika L, Choudhari A, Devi S, Kulsum F. Burns injury characteristics and outcomes at Lautoka Hospital, Fiji. Burns Open. 2025 Jan 1;9:100384.

Asefa L, Abebe MW, Negussie AG. Patterns and outcomes of pediatric burn injuries in a tertiary hospital’s burn unit. Burns Open. 2024 Apr 1;8(2):87-91.

Abul Barkat H, Abul Barkat M, Ali R, Hadi H, Kasmuri AR. Old wine in new bottles: Silver sulfadiazine nanotherapeutics for burn wound management. The International Journal of Lower Extremity Wounds. 2023 May 7:15347346231166980.

Mimura EC, Favoreto JP, Favero ME, Bonifacio KL, Peixe TS, Morita AA, Barbosa DS, Yabe MJ, Carrilho AJ. Silver serum levels in burned patients treated with silver sulfadiazine and its toxicity on inflammatory cells. Burns. 2020 Aug 1;46(5):1120-7.

Tashkandi H. Honey in wound healing: An updated review. Open life sciences. 2021 Oct 6;16(1):1091-100.

Almasaudi S. The antibacterial activities of honey. Saudi journal of biological sciences. 2021 Apr 1;28(4):2188-96.

Brudzynski K. A current perspective on hydrogen peroxide production in honey. A review. Food chemistry. 2020 Dec 1;332:127229.

Hixon KR, Klein RC, Eberlin CT, Linder HR, Ona WJ, Gonzalez H, Sell SA. A critical review and perspective of honey in tissue engineering and clinical wound healing. Advances in wound care. 2019 Aug 1;8(8):403-15.

Duncan CL, Enlow PT, Szabo MM, Tolchin E, Kelly RW, Castanon L, Aballay AM. A pilot study of the efficacy of active leptospermum honey for the treatment of partial-thickness facial burns. Advances in skin & wound care. 2016 Aug 1;29(8):349-55.

Ozturk F, Lozano AK, Ndayisenga C, Yilmaz AC. A Systematic Review of Honey’s Benefits for Burn Wound Treatment. Health Benefits of Honey and Propolis-Scientific Evidence and Medicinal Uses. 2024 Nov 13.

Cristea AG, Lisă EL, Iacob S, Dragostin I, Ștefan CS, Fulga I, Anghel AM, Dragan M, Morariu ID, Dragostin OM. Antimicrobial Smart Dressings for Combating Antibiotic Resistance in Wound Care. Pharmaceuticals. 2025 May 30;18(6):825..

Osman S, Umar H, Hashmi Y, Jawaid A, Ahmed Z. The efficacy of honey compared to silver sulfadiazine for burn wound dressing in superficial and partial thickness burns—a systematic review and meta-analysis. Trauma Care. 2022 Oct 6;2(4):523-34. doi.org/10.3390/traumacare2040043

Malik KI, Malik MN, Aslam A. Honey compared with silver sulphadiazine in the treatment of superficial partial‐thickness burns. International Wound Journal. 2010 Oct;7(5):413-7. doi: 10.1111/j.1742-481X.2010.00717.x

Mashhood AA, Khan TA, Sami AN. Honey compared with 1% silver sulfadiazine cream in the treatment of superficial and partial thickness burns. Journal of Pakistan Association of Dermatologists. 2017;16(1):14-19.

Mujalde VS, Jalaj A, Pipariya PR. To assess the efficacy of honey in comparison with 1% silver sulfadiazine cream as a burn wound dressing in superficial and partial thickness of burns. Sch J App Med Sci. 2014 Apr 9;2(1B):193-6. DOI: 10.36347/sjams.2014.v02i01.0040

Khan MI. Honey compared with silver sulphadiazine as burn wound dressing. Ann. Pak. Inst. Med. Sci. 2015;7(1):22-5.

Diamond A, Bowler M. Honey vs. silver sulfadiazine in the reepithelialization of partial-thickness burn wounds. . Posted online December 14, 2020. Available at https://commons.lib.jmu.edu/cgi/viewcontent.cgi?article=1010&context=pacapstones202029

Liche E, Zulu R, Kasongo ZM, Munthali JC. Effects of silver sulfadiazine and Actilite® honey on bacteria wound colonisation and wound healing in children with partial superficial burn wounds at University Teaching Hospital, Lusaka, Zambia. Medical Journal of Zambia. 2018;45(4):210-5.

Aziz Z, Hassan BA. The effects of honey compared to silver sulfadiazine for the treatment of burns: A systematic review of randomized controlled trials. Burns. 2017 Feb 1;43(1):50-7. doi.org/10.1016/j.burns.2016.07.004

Boekema BK, Chrysostomou D, Ciprandi G, Elgersma A, Vlig M, Pokorná A, Peters LJ, Cremers NA. Comparing the antibacterial and healing properties of medical-grade honey and silver-based wound care products in burns. Burns. 2024 Apr 1;50(3):597-610.

Wiguna KA, Siregar SP. Honey as a wound dressing on superficial partial-thickness burn injury in a resource-limited setting: An EBCR at Ende General Hospital. Svāsthya: Trends in General Medicine and Public Health. 2024 Nov 30;1(3):e73-78.

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Published

2025-10-21

How to Cite

1.
Mahek L, Bashir A, Shoukat Z, Iqbal F, Talat N. The Efficacy of Honey Compared to Silver Sulfadiazine in Pediatric Burn Wound Dressing in Superficial and Partial Thickness Burns. J Neonatal Surg [Internet]. 2025 Oct. 21 [cited 2026 Apr. 14];14(32S):8999-9004. Available from: https://jneonatalsurg.com/index.php/jns/article/view/9383

Issue

Vol. 14 No. 32S (2025): Journal of Neonatal Surgery

Section

Original Article

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