Cytohistopathological Correlation Of Breast Lesion In Konkan Region

Authors

  • Prutha Sharad Aware
  • Rahul Yeshwant sakpal
  • Amardeep Ajinath Patil
  • Vijay Dhondiraj Dombale

Keywords:

Fine Needle Aspiration Cytology, Breast Lesions, Malignant, Benign, Histopathology

Abstract

Objective: This study aimed to evaluate the diagnostic accuracy of Fine Needle Aspiration Cytology (FNAC) in palpable breast lumps and to correlate FNAC findings with histopathological diagnoses.

Methods: A retrospective observational study was conducted at B.K.L. Walawalkar Hospital and Research Center from January 2021 to October 2023. A total of 100 patients who underwent both FNAC and histopathology were included. Sensitivity, specificity, and diagnostic accuracy were calculated using histopathology as the gold standard.

Results: Of the 100 cases, 70 were benign and 30 were malignant. The sensitivity and specificity of FNAC were found to be 95% and 98%, respectively. The diagnostic accuracy for malignant cases was 97.5%. Most benign lesions were observed in the 31-40 years age group, while malignant lesions peaked in the 41-50 years group. FNAC findings showed strong concordance with histopathology, with 59 cases having biopsy confirmation.

Conclusion: FNAC is an effective, rapid, and minimally invasive diagnostic tool for distinguishing benign and malignant breast lesions. It shows high sensitivity and specificity, making it an invaluable tool in early breast cancer detection

Downloads

Download data is not yet available.

References

Krishnan S. Correlation of fine needle aspiration cytology (FNAC) with histopathology in palpable breast lesions: A study of 200 cases from a tertiary care center in South India. J Med Sci Clin Res. 2018;6(7).

Bhadani P, Shuchismita, Jamal I, Sinha R, Majumdar S. Reliability of fine needle aspiration cytology in the evaluation of palpable breast lumps – An institutional based study. Int J Med Res Health Sci. 2017;2:50–54.

Nggada H, Tahir M, Musa AB, Gali B, Mayun A, Pindiga U, et al. Correlation between histopathologic and fine needle aspiration cytology diagnosis of palpable breast lesions: a five-year review. Afr J Med Med Sci. 2007;36(4):295–298.

Paramesh, Saha A, Kariappa T. Correlation of fine needle aspiration cytology and histopathology in palpable breast lesions in 100 patients of KVG Medical College & Hospital, Sullia, Karnataka. Int J Appl Res. 2015;1:422–427.

Khattak M, Ahmad F. Role of fine needle aspiration cytology in diagnosis of palpable breast lesions and their comparison with histopathology. J Ayub Med Coll Abbottabad. 2020;32(1):83–86.

Agrawal N, Chaudhary S, Vardhan H. Palpable breast lumps fine needle aspiration cytology & histopathological correlation by United Kingdom National Health Service Breast Cancer Screening Programme. Int J Sci Res. 2015;4.

Cursi JAT, Marques MA, Castro CACAC, Schmitt F, Soares C. Fine-needle aspiration cytology (FNAC) is a reliable diagnostic tool for small breast lesions (≤ 1.0 cm): a 20-year retrospective study. Surg Exp Pathol. 2020;3:1–8.

Godhani A, Kagathara P. Cytomorphological patterns of palpable breast lesions diagnosed on fine needle aspiration cytology. Int J Med Rev Case Rep. 2022.

Ahmad F, Mittal A, Verma P, Kumar A, Awasthi S, Dutta S. Cytomorphological study of palpable breast lumps: Spectrum of lesions and diagnostic utility of FNAC. Ann Int Med Dent Res. 2016;2(4).

Madan M, Sharma M, Piplani S, Manjari M, Sharma N, Goyal S. Evaluation of fine needle aspiration cytology in the diagnosis of suspicious/gray zone lesions in breast lesions and its histopathological correlation. Ann Pathol Lab Med. 2016;3.

Thakkar BB, Parekh M, Trivedi NJ, Agnihotri A, Mangar U. Role of Fine Needle Aspiration Cytology in Palpable Breast Lesions and Its Correlation with Histopathological Diagnosis. J Med Res. 2014;4:283–288.

Pailoor K, Fernandes H, Jayaprakash CS, Marla N, Keshava SM. Fine needle aspiration cytology of male breast lesions - A retrospective study over a six year period. J Clin Diagn Res. 2014;8(10):FC13–15.

Ambawade VD, Das A. Correlative study of fine needle aspiration cytology and histopathology in breast lesions: A 2 year study. Int J Sci Res. 2018;7.

Odujoko OO, Omoniyi-Esan G, Komolafe AO, Sabageh D, Olaofe OO. The role of Fine Needle Aspiration Cytology in the diagnostic evaluation of palpable breast lesions seen in a low-resource hospital setting. Br J Med Med Res. 2016;16:1–7.

Akter S, Islam J, Haque S. Fine Needle Aspiration Cytology of Palpable Breast Lumps - Their Cytological Spectrum and Histopathological Correlation. KYAMC J. 2017;7(2):780-786.

Gupta G. Fine Needle Aspiration Cytology with Histopathologic Correlation in Breast Lesions. Indian J Pathol Res Pract. 2017;6(2):365-371.

Yip C, Jayaram G, Alhady S. The Experience with Fine Needle Aspiration Cytology in the Management of Palpable Breast Lumps in the University Hospital Kuala Lumpur. Med J Malaysia. 2000;55(3):363-367.

Pandey, A., Mishra, K., Gaur, B., & Singh, R. The diagnostic utility of FNAC in palpable lesions of breast at a tertiary care centre. The Journal of medical research. 2017; 5.

Downloads

Published

2025-08-21

How to Cite

1.
Aware PS, sakpal RY, Ajinath Patil A, Dombale VD. Cytohistopathological Correlation Of Breast Lesion In Konkan Region. J Neonatal Surg [Internet]. 2025Aug.21 [cited 2025Sep.21];14(2S):652-60. Available from: https://jneonatalsurg.com/index.php/jns/article/view/8934

Most read articles by the same author(s)