Neurodevelopmental Outcomes in Preterm Infants Receiving Kangaroo Mother Care: A Systematic Review
DOI:
https://doi.org/10.63682/jns.v14i32S.8837Keywords:
Kangaroo Mother Care, Preterm Infants, Neurodevelopment, Cognitive Development, Motor Skills, Emotional Regulation, Skin-to-Skin Contact, Neonatal Outcomes, Infant Brain Development, Systematic ReviewAbstract
Background: Kangaroo Mother Care (KMC) has been growing in popularity due to its unique practices of skin-to-skin contact and exclusive breastfeeding, alongside its many benefits to the wellbeing of pre-term infants. While previous research has acknowledged KMC's contributions in stabilizing vital signs and enhancing bonding, there is an increasing interest in its long-range effects on the neurodevelopmental outcomes of infants which include cognitive, motor, and emotional development. With this overarching goal, this systematic review aims to focus on literature discussing the developmental outcomes of preterm infants undergoing KMC.
Objective: To conduct a systematic review of the published literature on the impact of Kangaroo Mother Care on the neurodevelopmental outcomes, specifically cognitive, motor, and socio-emotional development, of preterm infants. This review intends to trace the circles of trends, gaps, or contradictions in the body of literature pertaining to early KMC implementation and their accrued outcomes in relation to neurodevelopment.
Methods: A search was performed using PubMed, Scopus, CINAHL, Google Scholar and Web of Science for articles published between the years 2010 to 2025. Studies that focused on preterm infants less than 37 weeks gestational age and performed KMC together with reporting on neurodevelopmental outcomes were considered for inclusion with criteria. Information was collected on the study’s design, sample size, implementation of the intervention, assessment tools used such as the Bayley Scales, and neurodevelopmental outcomes. Methodological quality was assessed using Newcastle-Ottawa Scale and Cochrane Risk of Bias tool. Where necessary, descriptive and correlation analyses complemented the adopted narrative synthesis approach.
Results: From the screened studies, a total of 58 were found to meet the set inclusion criteria. Most of the studies reported that KMC recipients demonstrated significantly better cognitive and motor skill development when compared with the conventional care groups. Emotional regulation, mother–infant bonding, and attentional responsiveness also showed positive
correlations with KMC exposure. Findings suggest that the enhancement in neurodevelopmental trajectories for KMC recipients is sustained with prolonged KMC, especially when it started in the first week of life.
Conclusions: This systematic review reinforces the evidence-based low-cost intervention nature of KMC, emphasizing its importance at this period of life. KMC not only physiologically stabilizes the babies but also tangibly positively influences their brain development. Longitudinal studies are needed to assess the impact of caregiver consistency, socio-cultural factors, and health system integration on the outcome sub-chronically expected with KMC
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Head, L.M., The effect of kangaroo care on neurodevelopmental outcomes in preterm infants. The Journal of perinatal & neonatal nursing, 2014. 28(4): p. 290-299.
Han, Z., et al., Meta-analysis of the Impact of Kangaroo Care on Physical Growth and Neurobehavioral Development in Premature Infants. Advances in Neonatal Care, 2025. 25(2): p. 162-172.
Wang, Y., et al., Positive effects of kangaroo mother care on long-term breastfeeding rates, growth, and neurodevelopment in preterm infants. Breastfeeding medicine, 2021. 16(4): p. 282-291.
Chung, E.H., J. Chou, and K.A. Brown, Neurodevelopmental outcomes of preterm infants: a recent literature review. Translational pediatrics, 2020. 9(Suppl 1): p. S3.
Aita, M., et al., Effectiveness of interventions on early neurodevelopment of preterm infants: a systematic review and meta-analysis. BMC pediatrics, 2021. 21(1): p. 210.
Ndjomo, G., et al., Neurodevelopment and Associated Factors in Preterm Infants Who Received Kangaroo Mother Care: A 12‐Month Follow‐Up. Acta Paediatrica, 2025.
Bisanalli, S., et al., The beneficial effect of early and prolonged kangaroo mother care on long‐term neuro‐developmental outcomes in low birth neonates–A cohort study. Acta Paediatrica, 2023. 112(11): p. 2400-2407.
Boundy, E.O., et al., Kangaroo mother care and neonatal outcomes: a meta-analysis. Pediatrics, 2016. 137(1).
Cheong, J.L., et al., Early environment and long-term outcomes of preterm infants. Journal of Neural Transmission, 2020. 127(1): p. 1-8.
Namazzi, G., et al., Neurodevelopmental outcomes of preterm babies during infancy in Eastern Uganda: a prospective cohort study. Global Health Action, 2020. 13(1): p. 1820714.
Gajula, R., et al., Kangaroo mother care in term and late preterm neonates: a systematic review. Cureus, 2024. 16(5).
Doddabasappa, P.N., et al., Effect of kangaroo mother care on neurodevelopmental outcome of low birth weight babies: a one-year randomized control trial. Int J Contemp Pediatr, 2018. 5(2): p. 508-14.
Mekonnen, A.G., S.S. Yehualashet, and A.D. Bayleyegn, The effects of kangaroo mother care on the time to breastfeeding initiation among preterm and LBW infants: a meta-analysis of published studies. International breastfeeding journal, 2019. 14: p. 1-6.
Palić, I., NEURODEVELOPMENTAL OUTCOME IN PRETERM INFANTS. Medicinski podmladak, 2024. 75(3): p. 43-49.
Krisli Serani, H.A., Syed Hyder Raza Naqvi,Shaheryar Shafqat,Avrina Kartika Ririe,Sudhair Abbas Bangash, Mechanisms Of Opioid-Induced Hyperalgesia: Implications For Chronic Pain Management. Journal of Neonatal Surgery, 2025.
Perero, J.D.T., S.J.P. Cordero, and M.A.O. Barco, Associated complications on neurodevelopmental effects in premature to term infants: systematic review. Archivos Venezolanos de Farmacologia y Terapéutica, 2022. 41(6): p. 425-431.
Cañadas, D.C., et al., Kangaroo mother care and skin-to-skin care in preterm infants in the neonatal intensive care unit: A bibliometric analysis. Archives de Pédiatrie, 2022. 29(2): p. 90-99.
Usac, G., The Impact of Nursing Education on the Implementation of Kangaroo Care: Neurodevelopment Outcomes in Preterm Infants. 2024.
de Castro Silva, M.G., et al., Kangaroo–mother care method and neurobehavior of preterm infants. Early human development, 2016. 95: p. 55-59.
Sarg, T., The Effects of Kangaroo Care on the Neurodevelopment of Preterm Infants in the Neonatal Intensive Care Unit (NICU). 2016.
Hilditch, C., et al., Effect of neonatal unit interventions designed to increase breastfeeding in preterm infants: An overview of systematic reviews. Neonatology, 2024. 121(4): p. 411-420.
Clarke-Sather, A.R., et al., Systematic Review of Kangaroo Care Duration's Impact in Neonatal Intensive Care Units on Infant–Maternal Health. American journal of perinatology, 2024. 41(08): p. 975-987.
Solaz-Garcia, A., et al., Impact of kangaroo care on premature infants’ oxygenation: systematic review. Neonatology, 2022. 119(5): p. 537-546.
Als, H. and G. B McAnulty, The newborn individualized developmental care and assessment program (NIDCAP) with kangaroo mother care (KMC): comprehensive care for preterm infants. Current women's health reviews, 2011. 7(3): p. 288-301.
Burstein, O., T. Aryeh, and R. Geva, Neonatal care and developmental outcomes following preterm birth: A systematic review and meta-analysis. Developmental Psychology, 2024.
Bueno-Pérez, I., et al., Impact of the Kangaroo mother care method on weight gain in premature newborns: systematic review. BMC Pediatrics, 2025. 25(1): p. 1-8.
Tessier, R., et al., Kangaroo Mother Care: A method for protecting high-risk low-birth-weight and premature infants against developmental delay. Infant Behavior and Development, 2003. 26(3): p. 384-397.
El-Farrash, R.A., et al., Longer duration of kangaroo care improves neurobehavioral performance and feeding in preterm infants: a randomized controlled trial. Pediatric Research, 2020. 87(4): p. 683-688.
Adejuyigbe, E., et al., Evaluation of the impact of continuous Kangaroo Mother Care (KMC) initiated immediately after birth compared to KMC initiated after stabilization in newborns with birth weight 1.0 to< 1.8 kg on neurodevelopmental outcomes: Protocol for a follow-up study. Trials, 2023. 24(1): p. 265.
Conde‐Agudelo, A., J.M. Belizán, and J. Diaz‐Rossello, Cochrane Review: Kangaroo mother care to reduce morbidity and mortality in low birthweight infants. Evidence‐Based Child Health: A Cochrane Review Journal, 2012. 7(2): p. 760-876.
Puthussery, S., et al., Effectiveness of early intervention programs for parents of preterm infants: a meta-review of systematic reviews. BMC pediatrics, 2018. 18: p. 1-18
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