Impact of Diabetes on the Efficacy of Drug-Eluting Stents (DES): A Meta-Analysis

Authors

  • Nandana Thekkepat Pillai

Keywords:

N\A

Abstract

The advent of drug-eluting stents (DES) revolutionized percutaneous coronary interventions (PCI) by reducing restenosis rates compared to bare-metal stents (BMS). However, diabetes mellitus (DM), a known independent risk factor for cardiovascular diseases, complicates the therapeutic outcomes post-DES implantation. This meta-analysis systematically reviews and analyzes clinical outcomes to assess whether diabetes compromises the efficacy of DES, focusing on restenosis rates, target lesion revascularization (TLR), stent thrombosis (ST), and major adverse cardiac events (MACE). Data from randomized controlled trials (RCTs) and observational studies (2005–2024) were aggregated and analyzed. The findings suggest that while DES offers significant benefits to diabetic patients, they remain at a higher risk of adverse outcomes compared to non-diabetic patients, warranting careful patient selection and post-implantation management...

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References

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Published

2025-08-06

How to Cite

1.
Thekkepat Pillai N. Impact of Diabetes on the Efficacy of Drug-Eluting Stents (DES): A Meta-Analysis. J Neonatal Surg [Internet]. 2025Aug.6 [cited 2025Oct.14];14(32S):7070-8. Available from: https://jneonatalsurg.com/index.php/jns/article/view/8759

Issue

Vol. 14 No. 32S (2025): Journal of Neonatal Surgery

Section

Original Article

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