Innovative Therapeutic Approach for Chronic and Acute Dermatitis: A Review of Recent Developments
DOI:
https://doi.org/10.63682/jns.v14i2S.8341Keywords:
Dermatitis due to contact, Atopic contact dermatitis, Irritant contact dermatitis, AllergensAbstract
Purpose of Review: Contact with allergens or irritants can cause "contact dermatitis" (CD), a collection of skin conditions. Contact dermatitis, which is brought on by coming into contact with a chemical, results from them. Similar to other forms of allergy, the illness develops in two stages: sensitization in the first phase and a cutaneous inflammatory response in the second step. Symptoms of allergic contact dermatitis might include acute, subacute, or chronic dermatitis.
Recent Findings: The current study examines the pathophysiology and current management of allergic contact dermatitis and makes predictions about the potential for more effective treatment in the future. Managing now plays greater importance in preventing problems before they start, especially in high-risk work environments. This includes focusing on education and awareness, as well as continuing to avoid irritants, use protective barriers, and regularly apply moisturisers.
Summary: A detailed history, the detection of allergic contact dermatitis is made by a physical examination and patch testing. Once the allergen has been identified, avoidance is the cornerstone of treatment. Management of contact dermatitis must include both medical care and, where appropriate occupational adjustments in order to lessen exposure to the causative agents. The existence of this treatable medical problem should be known to physicians
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References
Rios JL, Bas E, Recio MC. Effects of natural products on contact dermatitis. Current Medicinal Chemistry-Anti-Inflammatory & Anti-Allergy Agents. 2005 Feb 1;4(1):65-80.
Elmas ÖF, Akdeniz N, Atasoy M, Karadag AS. Contact dermatitis: A great imitator. Clinics in Dermatology. 2020 Mar 1;38(2):176-92.
Al-Otaibi ST, Alqahtani HA. Management of contact dermatitis. Journal of Dermatology & Dermatologic Surgery. 2015 Jul 1;19(2):86-91.
Nassau S, Fonacier L. Allergic contact dermatitis. Medical Clinics. 2020 Jan 1;104(1):61-76.
Tramontana M, Hansel K, Bianchi L, Sensini C, Malatesta N, Stingeni L. Advancing the understanding of allergic contact dermatitis: from pathophysiology to novel therapeutic approaches. Frontiers in Medicine. 2023 May 22;10:1184289.
Lachapelle, JM. Allergic contact dermatitis: clinical aspects. Rev Environ Health. (2014) 29:185–94. doi: 10.1515/reveh-2014-0055
Elmas ÖF, Akdeniz N, Atasoy M, Karadag AS. Contact dermatitis: A great imitator. Clinics in Dermatology. 2020 Mar 1;38(2):176-92
Patel K, Nixon R. Irritant contact dermatitis—A review. Current Dermatology Reports. 2022 Jun;11(2):41-51.
Slodownik D, Lee A, Nixon R. Irritant contact dermatitis: a review. Australasian Journal of Dermatology. 2008 Jan;49(1):1-1.
Usatine RP, Riojas M. Diagnosis and management of contact dermatitis. American family physician. 2010 Aug 1;82(3):249-55.
Dickel H. Management of contact dermatitis. Allergo Journal International. 2023 May;32(3):57-76.
Bourke J, Coulson I, English J. Guidelines for the management of contact dermatitis: an update. British Journal of Dermatology. 2009 May 1;160(5):946-54.
Saint-Mezard P, Rosieres A, Krasteva M, Berard F, Dubois B, Kaiserlian D, Nicolas JF. Allergic contact dermatitis. European Journal of Dermatology. 2004 Sep 1;14(5):284-95.
Imbesi S, Minciullo PL, Isola S, Gangemi S. Allergic contact dermatitis: Immune system involvement and distinctive clinical cases. Allergologia et Immunopathologia. 2011 Nov 1;39(6):374-7.
Havsteen, B.H. Pharmacol. Ther., 2002, 96, 67.
Carboni, G.P.; Contri, P.; Davalli, R. Contact Dermatitis, 1997, 36, 177.
Waclawski, E.R.; Aldridge, R. Contact Dermatitis, 1995, 33, 51.
Tanaka, S.; Otsuki, T.; Matsumoto, Y.; Hayakawa, R.; Sugiura, M. Contact Dermatitis, 2001, 44, 192.
Usatine RP, Riojas M. Diagnosis and management of contact dermatitis. American family physician. 2010 Aug 1;82(3):249-55.
Li Y, Li L. Contact dermatitis: classifications and management. Clinical Reviews in Allergy & Immunology. 2021 Dec;61(3):245-81.
Wigger-Alberti W, Elsner P. Preventive measures in contact dermatitis. Clinics in dermatology. 1997 Jul 1;15(4):661-5.
Lachapelle JM. Allergic contact dermatitis: clinical aspects. Reviews on Environmental Health. 2014 Aug 1;29(3):185-94.
Patel K, Nixon R. Irritant contact dermatitis—A review. Current Dermatology Reports. 2022 Jun;11(2):41-51.
Paravina M, Nedeva M, Bajić L. Contact dermatitis: A review of the literature with the connubial type in focus. Acta Medica Medianae. 2019;58(4):152-7.
Saint-Mezard P, Rosieres A, Krasteva M, Berard F, Dubois B, Kaiserlian D, Nicolas JF. Allergic contact dermatitis. European Journal of Dermatology. 2004 Sep 1;14(5):284-95.
DeKoven JG, Warshaw EM, Zug KA, Maibach HI, Belsito DV, Sasseville D, Taylor JS, Fowler JF, Mathias CT, Marks JG, Pratt MD. North American contact dermatitis group patch test results: 2015–2016. Dermatitis. 2018 Dec 1;29(6):297-309.
Parikh D, Dhar S, Srinivas S, Rammoorthy R, Sarkar R, Inamadar A, et al. Treatment guidelines for atopic dermatitis by Indian Society for Pediatric Dermatology task force 2016 - Part-2: topical therapies in atopic dermatitis. Indian J Paediatr Dermatol. (2017) 18:274–80. doi: 10.4103/ijpd.IJPD_99_17.
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