Analysis of Fetal MRI Use in Diagnosing Posterior Fossa Abnormalities
Keywords:
Posterior fossa, Fetal MRI, Ultrasound, Dandy–Walker malformation, Blake’s pouch cyst, Cerebellar vermis, Biometric measurements, Choroid plexus, Multimodal imaging, Diagnostic accuracyAbstract
This paper explores the clinical value of fetal magnetic resonance imaging in the diagnosis of the posterior fossa anomalies, as well as the limitations of sonography and the inconsistency of the diagnosis. It mentions six major findings that include the fact that ultrasound alone detects only 30-45 percent of abnormalities in the posterior fossa, but fetal MRI with Doppler ultrasound raises the accuracy of the test to 92 percent. Even early anatomical findings like the positioning of the choroid plexus are predictive in 95 percent of the malformation cases. A fraction of up to 34.5 percent of diagnoses is misclassified due to similarities in the characteristics and lack of standardization. In 86 percent of the cases with spina bifida, 7 associated CNS anomalies can be detected with MRI. The conclusions support the significance of well-integrated imaging procedures, biometric criteria, and multimodal methods. The research justifies the usefulness of fetal MRI as a critical modality in precise classification, prenatal counseling and making informed decisions in the assessment of the posterior fossa
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Aboughalia, H., Noda, S., Chapman, T., Revzin, M.V., Deutsch, G.H., Browd, S.R., Katz, D.S. and Moshiri, M., 2021. Multimodality imaging evaluation of fetal spine anomalies with postnatal correlation. Radiographics, 41(7), pp.2176-2192.
Alsehli, H., Alshahrani, S.M., Alzahrani, S., Ababneh, F., Alharbi, N.M., Alarfaj, N. and Baarmah, D., 2024. Fetal and neonatal outcomes of posterior fossa anomalies: a retrospective cohort study. Scientific Reports, 14(1), p.8411.
Amghar, A., El Abbassi, I., Mohammed, J., Asmaa, A., Amine, L. and Bouhya, S., 2024. Radiological characteristics of the posterior fossa of the fetal skull and presentation of a rare case of antenatal screening for Dandy-Walker malformation using antenatal fetal ultrasound and MRI. International Journal of Surgery Case Reports, 115, p.109037.
Bian, W., Zheng, W., Liu, Z., Luo, Q. and Sun, L., 2025. Utilization of MRI in Fetal Surgery. iRADIOLOGY.
Bowker, R.M., Marathu, K.K., Pharel, M., Adepoju, J.O., Vahedifard, F., Adler, S., Kocak, M., Liu, X. and Byrd, S.E., 2025. Utility of Biometric Measurements from Fetal Magnetic Resonance Imaging for Improved Antenatal Diagnosis of Dandy–Walker Spectrum Posterior Fossa Lesions. Diagnostics, 15(10), p.1295.
Bütün, Z., Kayapınar, M. and Şenol, G., 2025. Comparison of USG-MRI and post-natal results of Cases with anomalies detected in fetal CNS examination. Ginekologia Polska.
Chapman, T., Mirsky, D.M., Iruretagoyena, J.I. and Guimaraes, C.V., 2025. Prenatal diagnosis of infratentorial anomalies: ultrasound, fetal MRI, and implications for counseling. Pediatric Radiology, pp.1-20.
Dall'Asta, A., Grisolia, G., Volpe, N., Schera, G.B.L., Sorrentino, F., Frusca, T. and Ghi, T., 2021. Prenatal visualisation of the torcular herophili by means of a Doppler technology highly sensitive for low‐velocity flow in the expert assessment of the posterior fossa: a prospective study. BJOG: An International Journal of Obstetrics & Gynaecology, 128(2), pp.347-352.
Di Mascio, D., Rizzo, G., Khalil, A., D'Antonio, F., ENSO Working Group, Di Mascio, D., Rizzo, G., Khalil, A., Giancotti, A., Manganaro, L. and Visentin, S., 2023. Role of fetal magnetic resonance imaging in fetuses with congenital cytomegalovirus infection: multicenter study. Ultrasound in Obstetrics & Gynecology, 61(1), pp.67-73.
Duc, N.M., Nhung, N.T.H., My, T.T.T., Luu, D.T. and Van Lenh, B., 2021. Detecting fetal central nervous system anomalies using magnetic resonance imaging and ultrasound. Medical Archives, 75(1), p.45.
Eric Ozdemir, M., Demirci, O., Ayvaci Tasan, H., Ohanoglu, K. and Akalin, M., 2021. The importance of first trimester screening of cranial posterior fossa in predicting posterior fossa malformations which may be identified in the following weeks of gestation. Journal of Clinical Ultrasound, 49(9), pp.958-962.
Feng, L., Sun, L., Wang, J., Sun, C., Lu, L., Zhang, Z., Hu, Y. and Wu, Q., 2022. Qualitative and quantitative study of fetal posterior fossa during the first trimester in a Chinese population. BMC Pregnancy and Childbirth, 22(1), p.760.
Gupta, N., Martinez-Rios, C., El Demellawy, D., Barrowman, N. and Miller, E., 2021. Diagnostic Evaluation of the Posterior Fossa with Antenatal and Post-Mortem MRI: An Unfolded View. Journal of Fetal Medicine, 8(04), pp.279-291.
Jain, A. and Shankar, K., 2021. Antenatal Posterior Fossa Cystic Malformations. Perinatology, 21(4), pp.183-9.
Kutty, S., Clarke, G. and Kutty, J., 2022. Challenges in the pre-and post-natal diagnosis of posterior fossa cysts: A case report and review of historical evolution of descriptive terminologies. Surgical Neurology International, 13, p.449.
Mahalingam, H., Rangasami, R., Seshadri, S. and Suresh, I., 2021. Imaging spectrum of posterior fossa anomalies on foetal magnetic resonance imaging with an algorithmic approach to diagnosis. Polish journal of radiology, 86(1), pp.183-194.
Masselli, G., Cozzi, D., Ceccanti, S., Laghi, F., Giancotti, A. and Brunelli, R., 2021. Fetal body MRI for fetal and perinatal management. Clinical Radiology, 76(9), pp.708-e1.
Mckinnon, K., Kendall, G.S., Tann, C.J., Dyet, L., Sokolska, M., Baruteau, K.P., Marlow, N., Robertson, N.J., Peebles, D. and Srinivasan, L., 2021. Biometric assessments of the posterior fossa by fetal MRI: a systematic review. Prenatal diagnosis, 41(2), pp.258-270.
Miller, E., Orman, G. and Huisman, T.A., 2021. Fetal MRI assessment of posterior fossa anomalies: a review. Journal of Neuroimaging, 31(4), pp.620-640.
Mufti, N., Sacco, A., Aertsen, M., Ushakov, F., Ourselin, S., Thomson, D., Deprest, J., Melbourne, A. and David, A.L., 2022. What brain abnormalities can magnetic resonance imaging detect in foetal and early neonatal spina bifida: a systematic review. Neuroradiology, pp.1-13.
Nagaraj, U.D. and Kline-Fath, B.M., 2022. Clinical applications of fetal MRI in the brain. Diagnostics, 12(3), p.764.
Nagaraj, U.D., Kline-Fath, B.M., Horn, P.S. and Venkatesan, C., 2021. Evaluation of posterior fossa biometric measurements on fetal MRI in the evaluation of Dandy-Walker continuum. American Journal of Neuroradiology, 42(9), pp.1716-1721.
Nicolae, G.I.C.A., Panaitescu, A.M., Corina, G.I.C.A., Dumitru, A., Botezatu, R., Peltecu, G. and Vayna, A.M., 2022. Ultrasound appearance of fetal posterior fossa and a case report of prenatal diagnosis of Dandy-Walker malformation. Maedica, 17(2), p.505.
Schlatterer, S.D., Sanapo, L., du Plessis, A.J., Whitehead, M.T. and Mulkey, S.B., 2021. The role of fetal MRI for suspected anomalies of the posterior fossa. Pediatric Neurology, 117, pp.10-18.
Şeker, E., Aslan, B., Aydın, E. and Koç, A., 2023. Long-term outcomes of fetal posterior fossa abnormalities diagnosed with fetal magnetic resonance imaging. Journal of the Turkish German Gynecological Association, 24(1), p.28.
Taşdemir, Ü., Eyisoy, Ö.G., Karaman, A. and Demirci, O., 2025. Ultrasonographic evaluation of fetal posterior fossa anomalies: Six years experience of a tertiary center. Journal of Clinical Ultrasound, 53(1), pp.24-32.
Volpe, P., De Robertis, V., Volpe, G., Boito, S., Fanelli, T., Olivieri, C., Votino, C. and Persico, N., 2021. Position of the choroid plexus of the fourth ventricle in first‐and second‐trimester fetuses: a novel approach to early diagnosis of cystic posterior fossa anomalies. Ultrasound in Obstetrics & Gynecology, 58(4), pp.568-575.
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