A Study on Effect of Nasal Obstruction on Pulmonary Function Tests in Patients with Allergic Nasal Polyposis Attending Medical College Headquarter’s Hospital

Authors

  • Kukkapalli Prathap Kumar
  • Nagisetty Sindhuja
  • Dudekula Arshad
  • B.S. Sindhu

Abstract

Both the upper and lower airways form a contiguous and functionally related organ. Nose performs important functions such as respiration, filtration, humidification and olfaction.[1]Nasal polyposis, is one of the common cause for nasal obstruction. Due to obstruction particles enters the lower airway through oral breathing and causes bronchoconstriction and lower airway irritation.[2] Hence, there seems a relation between upper and lower airways.[3]

Aim of the study is to evaluate the impact of nasal obstruction on pulmonary function in patients with allergic nasal polyposis by comparing pulmonary function test (PFT) results before and after surgical intervention.

Materials and Methods: This study was conducted on patients aged 20 to 45 years who attended the Department of ENT at Medical College Hospital. A total of 86 patients diagnosed with nasal polyposis were included. All participant underwent surgical intervention and pulmonary function tests (PFTs) were performed at three intervals: preoperatively, and 1 and 3 month postoperatively and results were analyzed and compared.

Results: The majority of patients affected by allergic nasal polyposis belonged to the age group around 30 years. The mean age of the study population was 31.09 years. All patients (100%) underwent functional endoscopic sinus surgery. Postoperative evaluation revealed clinically and statistically significant improvements in forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) irrespective of age, gender, or the duration of nasal obstruction.

Conclusion: Patients with bilateral nasal obstruction with decreased pulmonary function  had significant improvement in pulmonary function  after nasal surgery.

Downloads

Download data is not yet available.

References

Cao Y, Hong H, Sun Y, Lai Y, Xu R, Shi J, Chen F. The effects of endoscopic sinus surgery on pulmonary function in chronic rhinosinusitis patients with asthma: a systematic review and meta-analysis. Eur Arch Otorhinolaryngol. 2019 May;276(5):1405-1411. doi: 10.1007/s00405-019-05337-4. Epub 2019 Feb 25. PMID: 30799521.

Liu Y, Sha J, Meng C, Zhu D. Mechanism of Lower Airway Hyperresponsiveness Induced by Allergic Rhinitis. J Immunol Res. 2022 Jul 12;2022:4351345. doi: 10.1155/2022/4351345. PMID: 35865653; PMCID: PMC9296291.

Licari A, Castagnoli R, Denicolò CF, Rossini L, Marseglia A, Marseglia GL. The Nose and the Lung: United Airway Disease? Front Pediatr. 2017 Mar 3;5:44.

Feng CH, Miller MD, Simon RA. The united allergic airway: connections between allergic rhinitis, asthma, and chronic sinusitis. Am J Rhinol Allergy. 2012;26(3):187–90.

Pendolino AL, Scarpa B, Ottaviano G. Relationship Between Nasal Cycle, Nasal Symptoms and Nasal Cytology. Am J Rhinol Allergy. 2019 Nov;33(6):644-649. doi: 10.1177/1945892419858582. Epub 2019 Jun 20. PMID: 31219310; PMCID: PMC7207008.

Gupta M, Singh S, Chauhan B. Comparative study of complete nasal packing with and without airways. B-ENT. 2011;7(2):91–6

Yiğit O, Cinar U, Uslu B, Akgül G, Topuz E, Dadaş B. [The effect of nasal packing with or without an airway on arterial blood gases during sleep]. Kulak Burun Bogaz Ihtis Derg KBB J Ear Nose Throat. 2002;9(5):347–50.

Sobh E, Elhussieny F, Ismail T. Elimination of nasal obstruction improves pulmonary functions and oxygenation. Egypt J Bronchol. 2021 Jun 22;15(1):32.

Gudiseva A, Ramaswamy B, Singh R, Dalakoti P. Comparative Study of Nasal Symptoms and Pulmonary Function Tests Post FESS in Ethmoidal Polyposis. Indian J Otolaryngol Head Neck Surg. 2019 Nov;71(Suppl 3):2000–3.

Liu Y. [Study on the correlation between the severity of chronic rhinosinusitis and bronchial asthma and pulmonary function]. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi J Clin Otorhinolaryngol Head Neck Surg. 2015 Jul;29(13):1206–8.

Kariya S, Okano M, Oto T, Higaki T, Makihara S, Haruna T, et al. Pulmonary function in patients with chronic rhinosinusitis and allergic rhinitis. J Laryngol Otol. 2014 Mar;128(3):255–62.

Rix I, Håkansson K, Larsen CG, Frendø M, von Buchwald C. Management of chronic rhinosinusitis with nasal polyps and coexisting asthma: A systematic review. Am J Rhinol Allergy. 2015;29(3):193–201.

Baharmand I, Sheikh-Oleslami S, Pascual Rodríguez A, Hernaiz-Leonardo JC, Alim BM, Javer AR. The Effects of Nasal Surgery on Pulmonary Function: A Systematic Review and Meta-Analysis. The Laryngoscope. 2023;133(11):2837– 45.

Downloads

Published

2025-07-09

How to Cite

1.
Kumar KP, Sindhuja N, Arshad D, Sindhu B. A Study on Effect of Nasal Obstruction on Pulmonary Function Tests in Patients with Allergic Nasal Polyposis Attending Medical College Headquarter’s Hospital. J Neonatal Surg [Internet]. 2025Jul.9 [cited 2025Oct.9];14(32S):4452-9. Available from: https://jneonatalsurg.com/index.php/jns/article/view/8132

Issue

Vol. 14 No. 32S (2025): Journal of Neonatal Surgery

Section

Original Article

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

You are free to:

  • Adapt — remix, transform, and build upon the material for any purpose, even commercially.

Terms:

  • Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.