Macular Thickness Changes Following Phacoemulsification In Diabetic And Non Diabetic Patients - An Optical Coherence Tomography (OCT) Guided Tertiary Care Centre Study
Keywords:
Phacoemulsification, Diabetic Maculopathy, Optical Coherence Tomography (OCT), Macular ThicknesAbstract
Background: Cataract is a leading cause of reversible blindness, and its coexistence with diabetes mellitus poses challenges in post-operative recovery due to the risk of macular edema. Optical coherence tomography (OCT) has emerged as a valuable tool to evaluate subtle retinal changes.
Objective: This study aims to assess and compare the macular thickness changes following phacoemulsification in type 2 diabetic and non-diabetic cataract patients, and to correlate these changes with glycemic control.
Methods: A prospective case-control study was conducted over 18 months at a tertiary care center involving 180 patients, equally divided into diabetic and non-diabetic groups. Preoperative and postoperative macular thickness measurements were performed using OCT at baseline, 1 week, 4 weeks, and 12 weeks after phacoemulsification. Blood sugar profiles, including HbA1c, were evaluated. Statistical analyses was conducted to assess correlations between glycemic control and macular changes.
Results: While preoperative macular parameters were similar between the two groups, diabetic patients demonstrated significantly higher central macular thickness and macular cube volume at 1 week post-surgery (p<0.05). Poorly controlled diabetics (HbA1c ≥6.5%) exhibited greater macular thickening compared to those with better glycemic control. However, by 12 weeks, differences in macular thickness between groups were statistically non-significant.
Conclusion: Diabetic patients, especially those with poor glycemic control, are at increased risk for early postoperative macular thicknesschanges following phacoemulsification. OCT monitoring and optimal blood sugar control are help to ensure favorable visual outcomes in these patients
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Mohammed madeehhassanin, m., khedr mohamed, m., mohamed-aly ibrahim, m. (2021). 'macular thickness changes in diabetic versus non diabetic patients after uncomplicated phacoemulsification', Al-Azhar Medical Journal, 50(2), pp. 1103-1118. doi: 10.21608/amj.2021.158459
AkarsuAçar ÖP, Olgun A, Ergen E, Demir AG, Güven D. Evaluation of Changes in Macular Thickness Using Optical Coherence Tomography After Cataract Surgery in Diabetic and Nondiabetic Patients. JAREM 2019; 9(1): 32-7.
Archana ShrimantBhadikar, Ravindra Galphade, Shrikant Joshi, Nikhil Beke. Effect of uneventful phacoemulsification cataract surgery in diabetic and non-diabetic patients on central macular thickness: A comparative study. MedPulse International Journal of Ophthalmology. July 2019; 11(1): 09-14.
Dr. Anant Singhi , Dr. Kabita Bora Baishya 1Registrar, Regional Institute of Ophthalmology, Gauhati Medical College and Hospital, Guwahati 32, Assam, India 2Associate Professor, Regional Institute of Ophthalmology, Gauhati Medical College and Hospital, Guwahati 32, Assam, India.
Aguilar, Romulo &Protacio, Jesa&Protasio, Jesa. (2016). Glycemic Control and Changes in Macular Thickness after Phacoemulsification in Diabetics. Philippine Journal of Ophthalmology. 41. 2-9.
Rong X, Rao J, Li D, Jing Q, Lu Y, Ji Y. TRIM69 inhibits cataractogenesis by negatively regulating p53. Redox Biol. 2019 Apr;22:101157. [PMC free article] [PubMed]
Wang et al Aphanothece sacrum on Diabetic Cataracts]. YakugakuZasshi. 2019;139(3):381-384. [PubMed]
Lobo et al Aly MG, Shams A, Fouad YA, Hamza I. Effect of lens thickness and nuclear density on the amount of laser fragmentation energy delivered during femtosecond laser-assisted cataract surgery. J Cataract Refract Surg. 2019 Apr;45(4):485-489. [PubMed]
Kim et al Chylack Ren Y, Fang X, Fang A, Wang L, Jhanji V, Gong X. Phacoemulsification With 3.0 and 2.0 mm Opposite Clear Corneal Incisions for Correction of Corneal Astigmatism. Cornea. 2019 Sep;38(9):1105-1110. [PubMed]
Kim et Klein Lee MD, Chen SP, Chen TA, Leibold C, Li Z, Fisher AC, Lin CC, Singh K,
Sadda sr. Characteristics of cataract surgery patients influencing patient satisfaction scores. J Cataract Refract Surg. 2019 Apr;45(4):437-442. [PMC free article] [PubMed].
Kim et al Alsarhani D K, Altammami G S, Alzahrani H T, et al. (October 12, 2022) Outcomes of Cataract Surgery in Diabetic Patients in King Abdulaziz Medical City in 2019. Cureus 14(10): e30216. DOI 10.7759/cureus.30216.
Zhang et al Alsarhani D K, Altammami G S, Alzahrani H T, et al. (October 12, 2022) Outcomes of Cataract Surgery in Diabetic Patients in King Abdulaziz Medical City in 2019. Cureus 14(10): e30216. DOI 10.7759/cureus.30216.
Lobo et al AmeriGolestan, Z., Moghadas Sharif, N., Shoeibi, N., Ehsaei, A., Eslampour, A., Kadkhoda, M., HeravianShandiz, J. Effect of Phacoemulsification on Macular Thickness and Volume in Diabetic Patients without Retinopathy. Reviews in Clinical Medicine, 2020; 7(1): 10-14. doi: 10.22038/rcm.2020.47370.1312.
William et alGlycemic Control and Changes in Macular Thickness after Phacoemulsification in Diabetics. Philippine Journal of Ophthalmology. 41. 2-9.
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