Formulation and Evaluation of Herbal Cream from Ivy Gourd and Other Natural Excipients
Keywords:
N\AAbstract
The acceptance and appeal of cosmetic formulations based on herbs have significantly increased in recent years. Products that are seen as natural, secure, and eco-friendly are becoming more and more popular. Herbal cosmetics are preferred not only because they have few adverse effects but also because they are biocompatible with the skin and can provide therapeutic benefits by using bioactive chemicals obtained from plants. Coccinia grandis, also referred to as Ivy gourd, is one of the many medicinal plants being investigated for cosmeceutical uses. A member of the Cucurbitaceae family, this climbing vine has long been utilized in herbal medicine systems to treat infections, inflammation, and skin conditions. Its antibacterial, antioxidant, and anti-inflammatory qualities are attributed to the abundance of phytochemicals found in its leaves, including flavonoids, alkaloids, tannins, and saponins. The development and assessment of a topical herbal cream with Ivy gourd extract as the main active ingredient is the main goal of this study. To improve the cream's moisturizing, restorative, and protecting qualities, additional natural excipients have been added to the recipe in addition to Ivy gourd, including aloe vera gel, beeswax, shea butter, and coconut oil. Careful plant material extraction, emulsion preparation, and natural base mixing are all steps in the formulation process. Numerous physicochemical and microbiological evaluation factors, including pH, spreadability, viscosity, stability, and antibacterial activity, are also described in this article. The encouraging outcomes of these evaluations demonstrate the potential of Ivy gourd as a key botanical ingredient in the creation of herbal skincare products that are sustainable, safe, and efficacious
Downloads
References
Pekamwar SS, Kalyankar TM, Kokate SS, School of Pharmacy, Swami Ramanand Teerth Marathwada University, Nanded-431606, Maharashtra, India. Pharmacological Activities of Coccinia grandis: review [Internet]. Vol. 05, Journal of Applied Pharmaceutical Science. 2013 May p. 114–9. Available from: https://japsonline.com/admin/php/uploads/908_pdf.pdf
Nagare S PhD, Deokar GS, Nagare R, Phad N. REVIEW ON COCCINIA GRANDIS (L) VOIGT (IVY GOURD) [Internet]. Vols. 4–4, Sujata World Journal of Pharmaceutical Research. 2015 p. 728–43. Available from: https://www.wjpr.net
Muniappan R, Reddy GVP, Raman A. Coccinia grandis (L.) Voigt (Cucurbitaceae). In: Cambridge University Press eBooks [Internet]. 2019. p. 175–82. Available from: https://doi.org/10.1017/cbo9780511576348.010
Farrukh U, Shareef H, Mahmud S, Ali SA, Saudi Basic Industries Corporation (SABIC), Rizwani GH. Antibacterial activities of Coccinia grandis L. Pakistan Journal of Botany. 2018;1259–62.
Nammas M. Systematic Review of Plant-Based Excipients in Topical Drug Delivery. Ibnosina Journal of Medicine and Biomedical Sciences [Internet]. 2024 Nov 12; Available from: https://doi.org/10.1055/s-0044-1791500
R P, G VK. Coccinia indica: A Comprehensive Review of Pharmacology, Therapeutic Applications, Nutritional Potentials, and Future Prospects. The Journal of Phytopharmacology [Internet]. 2022 Jun 7;11(3):211–6. Available from: https://doi.org/10.31254/phyto.2022.11313
Sakharkar P, Chauhan B. Antibacterial, antioxidant and cell proliferative properties of Coccinia grandis fruits.Avicenna J Phytomed, 2017; 7 (4): 295-307.
Arunachalam R, Dhanasingh S, Kalimuthu B, Uthirappan M, Rose C, Mandal AB. Phytosynthesis of silver nanoparticles using Coccinia grandis leaf extract and its application in the photocatalytic degradation. Colloids and Surfaces B Biointerfaces [Internet]. 2012 Feb 3;94:226–30. Available from: https://doi.org/10.1016/j.colsurfb.2012.01.040
Meenatchi P, Purushothaman A, Maneemegalai S. Antioxidant, antiglycation and insulinotrophic properties of Coccinia grandis (L.) in vitro: Possible role in prevention of diabetic complications. Journal of Traditional and Complementary Medicine [Internet]. 2016 Mar 2;7(1):54–64. Available from: https://doi.org/10.1016/j.jtcme.2016.01.002
Waisundara VY, Watawana MI, Jayawardena N. Costus speciosus and Cocciniagrandis : Traditional medicinal remedies for diabetes. South African Journal of Botany [Internet]. 2015 Feb 11;98:1–5. Available from: https://doi.org/10.1016/j.sajb.2015.01.012
Rahmatullah M, Biplob K. An evaluation of antihyperglycemic and antinociceptive effects of crude methanol extract of Coccinia grandis (L.) J. voigt. (Cucurbitaceae) leaves in Swiss albino mice. Advances in Natural and Applied Sciences. 2011;5(1):1–5.
Munasinghe M a. a. K, Abeysena C, Yaddehige IS, Vidanapathirana T, Piyumal KPB. Blood Sugar Lowering Effect ofCocciniagrandis(L.) J. Voigt: Path for a New Drug for Diabetes Mellitus. Experimental Diabetes Research [Internet]. 2011 Jan 1;2011:1–4. Available from: https://doi.org/10.1155/2011/978762
Hossain SkA, Uddin SrN, Salim MdA, Haque R. Phytochemical and Pharmacological screening of Coccinia grandis Linn. Journal of Scientific and Innovative Research.2019;3:65–71.
Trinh PTN, Nguyen TQ, Van Hau N, Hung QT, Van Du C, Tuan NT, et al. Chemical constituents of the stem of Coccinia grandis. IOP Conference Series Materials Science and Engineering [Internet]. 2020 Jan 1;736(2):022080. Available from: https://doi.org/10.1088/1757-899x/736/2/022080
Downloads
Published
How to Cite
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
Terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.