Preformulation Profiling of Capecitabine: Foundation for Novel Oral Anticancer Drug Delivery Systems

Authors

  • Jatin Kumar Jamdar
  • Vaishali Tandekar
  • Muktamadhavi
  • Bhupendra Giri
  • Vijay Kumar Prajapati
  • Suchita Kujur
  • Harish Sharma
  • Gyanesh Kumar Sahu

Abstract

A crucial stage in creating a stable and efficient pharmaceutical formulation is preformulation studies. The preformulation study on capecitabine, a parenteral antineoplastic medication used to treat colorectal cancers, is the main subject of this work.The physicochemical characterization included solubility, partition coefficient, melting point, ultraviolet-visible spectroscopy, infrared/fourier transform infrared, X-ray diffraction, and high performance liquid chromatography.The findings give critical information for developing a strong and bioavailable formulation that ensures therapeutic efficacy while retaining stability and compatibility. This study serves as a platform for future formulation development and optimization of capecitabine-based medicines.

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References

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Published

2025-07-01

How to Cite

1.
Jamdar JK, Tandekar V, Muktamadhavi M, Giri B, Prajapati VK, Kujur S, Sharma H, Sahu GK. Preformulation Profiling of Capecitabine: Foundation for Novel Oral Anticancer Drug Delivery Systems. J Neonatal Surg [Internet]. 2025Jul.1 [cited 2025Jul.12];14(32S). Available from: https://jneonatalsurg.com/index.php/jns/article/view/7753

Issue

Vol. 14 No. 32S (2025): Journal of Neonatal Surgery

Section

Original Article

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Copyright (c) 2025 Jatin Kumar Jamdar, Vaishali Tandekar, Muktamadhavi, Bhupendra Giri, Vijay Kumar Prajapati, Suchita Kujur, Harish Sharma, Gyanesh Kumar Sahu

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