Phytochemical Analysis, Antioxidant Properties, and Anti-Gout Activity of Cucumis meloagrestis and Albizia thompsonii Extracts

Authors

  • Pratik P. Terse
  • Sushil Bhargava
  • Sachin Chandavarkar

Keywords:

Cucumis meloagrestis, Albizia thompsonii, antioxidant activity, anti-gout, phytochemical analysis, anti-inflammatory properties

Abstract

This study investigates the phytochemical composition, antioxidant properties, and anti-gout activity of Cucumis meloagrestis and Albizia thompsonii extracts. Both plants, traditionally used for their medicinal properties, were analyzed for their bioactive compounds, including flavonoids, phenolic acids, tannins, and saponins. The total phenolic content (TPC) in C. meloagrestis ranged from 206.07 to 222.2 mg/g, while A. thompsonii exhibited TPC levels between 150 to 155 mg/g. These phytochemicals demonstrated robust antioxidant activity, with significant free radical scavenging capabilities, as confirmed by DPPH, ABTS, and FRAP assays. The study also explored the anti-gout potential of these plants, particularly focusing on their ability to reduce uric acid levels and mitigate oxidative stress. Hydrolysates from both plants, treated with alcalase, showed the highest anti-gout activity in the 5–10 kDa molecular weight fraction. Furthermore, the extracts exhibited strong anti-inflammatory properties, inhibiting enzymes such as COX and LOX. These findings suggest that C. meloagrestis and A. thompsonii are promising sources of bioactive compounds with potential therapeutic applications for antioxidant, anti-inflammatory, and anti-gout treatments..

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Published

2025-06-20

How to Cite

1.
P. Terse P, Bhargava S, Chandavarkar S. Phytochemical Analysis, Antioxidant Properties, and Anti-Gout Activity of Cucumis meloagrestis and Albizia thompsonii Extracts. J Neonatal Surg [Internet]. 2025Jun.20 [cited 2025Jul.15];14(32S):1174-88. Available from: https://jneonatalsurg.com/index.php/jns/article/view/7521

Issue

Vol. 14 No. 32S (2025): Journal of Neonatal Surgery

Section

Original Article

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