Fabrication Of Cobalt Oxide Nanoparticles Using Barringtonia Acutangula For Evaluation Of Antibacterial, Antioxidant And Protein Denaturation Activities

Authors

  • Jeyapaul Ashli
  • Subramanian Priya Velammal
  • Thomas Peter Amaladhas

Keywords:

Barringtonia acutangla, Nanocobalt oxide particles, Antibacterial activity, Antioxidant activity, Protein denaturation studies

Abstract

Nanocobalt oxide particles were fabricated through an uncomplicated and sustainable process using dried fruit extract from Barringtonia acutangula. The successful formation of nanoparticles was evidenced by a characteristic absorption band observed between 300 to 750 nm. The presence of natural phytochemicals such as polyphenols and triterpenoids, which served as stabilizing agents by binding to the nanoparticle surface and supporting the formation of a stable Cobalt oxide lattice was confirmed using FTIR analysis. XRD analysis revealed the crystalline structure consistent with cobalt oxide. SEM images showed that the nanoparticles exhibited rough and irregular surface morphologies. EDX analysis confirmed uncontaminated state of the sample. The size was calculated to be 43 nm using TEM analysis. Additionally, the Cobalt oxide nanoparticles produced through the biological method worked against four different bacterial strains. They showed 91.27 % antioxidant activity and 59.6 % inhibition activity.

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References

Patil, S. S., Shedbalkar, U. U., Truskewycz, A., Chopade, B. A., & Ball, A. S. (2018). Nanoparticles for environmental clean-up: A review of potential risks and emerging solutions. Environmental Technology & Innovation, 11, 251–269.

Iravani, S. (2011). Green synthesis of metal nanoparticles using plants. Green Chemistry, 13(10), 2638–2650.

Ahmed, S., Saifullah, Ahmad, M., Swami, B. L., & Ikram, S. (2016). Green synthesis of silver nanoparticles using Azadirachta indica aqueous leaf extract. Journal of Radiation Research and Applied Sciences, 9(1), 1–7.

Singh, J., Dutta, T., Kim, K. H., Rawat, M., Samddar, P., & Kumar, P. (2018). 'Green' synthesis of metals and their oxide nanoparticles: applications for environmental remediation. Journal of Nanobiotechnology, 16(1), 84.

Rajendran, L., & Muthuraman, G. (2020). Green synthesis and characterization of cobalt oxide nanoparticles using Solanum nigrum leaf extract for electrochemical applications. Materials Research Express, 7(1), 015054.

Ganesan Vanangamudi, Muthuvel Subramanian, Ganesamoorthy Thirunarayanan, Synthesis, spectral linearity, antimicrobial, antioxidant and insect antifeedant activities of some 2,5-dimethyl-3-thienyl chalcones,Arabian Journal of Chemistry, Volume 10, Supplement 1, 2017, Pages S1254-S1266, ISSN 1878-5352, https://doi.org/10.1016/j.arabjc.2013.03.006.

Md. Nur Alam, Nusrat Jahan Bristi, Md. Rafiquzzaman, Review on in vivo and in vitro methods evaluation of antioxidant activity, Saudi Pharmaceutical Journal, Volume 21, Issue 2, 2013, Pages 143-152, ISSN 1319-0164, https://doi.org/10.1016/j.jsps.2012.05.002.

D.Barreca, C.Massignan, S.Daolio, M.Fabrizio, C.Piccirillo, L.Armelao, E.Tondello, Composition and microstructure of cobalt oxide thin films obtained from a novel cobalt (II) precursor by chemical vapor deposition, Chem.Mater.13(2001)588–593.

M. Lenglet, C.K.Jørgensen, Reinvestigation of the optical properties of Co3O4, Chem.Phys.Lett. 229(1994)616–620.

A. Gulino, P.Dapporto, P.Rossi, I.Fragalà, A novel self-generating liquid MOCVD precursor for Co3O4 thin films , Chem.Mater.15(2003)3748–3752.

Naveen, Nirmalesh. (2014). Investigation on physiochemical properties of Mn substituted spinel cobalt oxide for supercapacitor applications. Electrochimica Acta. 125. 404-414. 10.1016/j.electacta.2014.01.161.

Deori, Dr. Kalyanjyoti & Deka, Sasanka. (2013). Morphology oriented surfactant dependent CoO and reaction time dependent Co3O4 nanocrystals from single synthesis method and their optical and magnetic properties. CrystEngComm. 15. 10.1039/C3CE41502C.

Ahmad, Md. Hasive & Islam, Md Roxy & Muhammad, · & Islam, Rakibul. (2024). Improved Electrochemical Performance of Co3O4 Incorporated MnO2 Nanowires for Energy Storage Applications. Arabian Journal for Science and Engineering. 50. 10.1007/s13369-024-09421-8.

Muhammad, Hafeez & Shaheen, Ruzma & Akram, Bilal & Abdin, Zain & Haq, Sirajul & Mahsud, Salahudin & Ali, Shaukat & Taj, Rizwan. (2020). Green Synthesis of cobalt oxide nanoparticles for potential biological applications. Materials Research Express. 7. 10.1088/2053-1591/ab70dd.

Manh, D.H. & Nhã, Trần & Le, Phong & Nam, Pham & Thanh, T. & Pham Thanh, Phong. (2023). Determination of the crystalline size of hexagonal La1−xSrxMnO3 (x = 0.3) nanoparticles from X-ray diffraction – a comparative study. RSC Advances. 13. 25007-25017. 10.1039/d3ra04018f.

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Published

2025-06-09

How to Cite

1.
Ashli J, Priya Velammal S, Amaladhas TP. Fabrication Of Cobalt Oxide Nanoparticles Using Barringtonia Acutangula For Evaluation Of Antibacterial, Antioxidant And Protein Denaturation Activities. J Neonatal Surg [Internet]. 2025Jun.9 [cited 2025Jun.20];14(31S):495-506. Available from: https://jneonatalsurg.com/index.php/jns/article/view/7199