Formulation And Evaluation Of Terminalia Arjuna-Based Oral Suspension For Anti-Inflammatory Activity

Authors

  • Ayush Verma
  • Girish Kumar Vyas
  • Nitin Nama

Keywords:

Terminalia arjuna, oral suspension, anti-inflammatory, formulation stability, in vitro drug release

Abstract

The study focuses on the development and evaluation of an oral suspension containing Terminalia arjuna extract, a plant renowned for its anti-inflammatory, cardioprotective, and antioxidant properties. The formulation aimed to provide a stable, effective, and easily administered dosage form for potential cardiovascular health support. The extract was prepared from the bark of T. arjuna using ethanol, and the suspension was formulated with excipients like xanthan gum, sucrose, and preservatives. The final product was evaluated for physicochemical properties, stability, microbial safety, and in vitro drug release. Results indicated that the optimal formulation (F2) showed excellent stability, uniform drug content, and sustained release, with 80.5% drug release after 120 minutes. The formulation met all evaluation criteria, demonstrating its potential as a safe and effective therapeutic option for inflammation and cardiovascular conditions.

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References

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Published

2025-06-05

How to Cite

1.
Verma A, Kumar Vyas G, Nama N. Formulation And Evaluation Of Terminalia Arjuna-Based Oral Suspension For Anti-Inflammatory Activity. J Neonatal Surg [Internet]. 2025Jun.5 [cited 2025Jun.20];14(31S):59-64. Available from: https://jneonatalsurg.com/index.php/jns/article/view/7083