A Comparative Study of Vaccinated and Non-Vaccinated Covid-19 Cases Against Klebsiella Pneumoniae
Keywords:
UTI Urinary Tract Infections- K.pn - Klebsiella pneumoniaeAbstract
A Comparative study of COVID- 19 vaccinated individuals against bacterial co-infections could explore valuable insights such as the effectiveness of vaccines in preventing secondary infections, comparative analysis of bacterial infection rates between vaccinated and unvaccinated populations and the COVID-19 vaccines impact the incidence of specific bacterial infections, such as Klebsiella pneumoniae. The start of the COVID-19 pandemic brought about new healthcare challenges, with secondary bacterial infections in hospitalized patients posing additional health threats. In the present cohort study, we analyzed the infection rates of Klebsiella pneumoniae between vaccinated and unvaccinated groups of COVID-19 vaccination for long COVID patients from July 2022 to June 2024. A total of 254 patients in and around Madurai district were collected based on patient demographics such as age, sex, underlying health conditions, vaccination status and district wise distribution of the samples were processed as per standard microbiological techniques
Downloads
References
Jondle CN, Gupta K, Mishra BB, Sharma J. Klebsiella pneumoniae infection of murine neutrophils impairs their efferocytic clearance by modulating celldeath machinery. PLoS Pathog.2018 Oct;14(10): e1007338. [PMC free article:PMC6181436][PubMed:30273394]
Aghamohammad S, Badmasti F, Solgi H, Aminzadeh Z, Khodabandelo Z, Shahcheraghi F. First Report of Extended-Spectrum Betalactamase-Producing Klebsiella pneumoniae Among Fecal Carriage in Iran: High Diversity of Clonal Relatedness and Virulence Factor Profiles. Microb Drug Resist. 2020 Mar;26(3):261-269. [PubMed: 30277830]
Rønning TG, Aas CG, Støen R, Bergh K, Afset JE, Holte MS, Radtke A. Investigation of an outbreak caused by antibiotic-susceptible Klebsiella oxytoca in a neonatal intensive care unit in Norway. ActaPaediatr. 2019 Jan;108(1):76-82. [PubMed: 30238492]
Tsereteli M, Sidamonidze K, Tsereteli D, Malania L, Vashakidze E.epidemiology of carbapenem-resistant Klebsiella pneumoniae in intensive care units of multiprofile hospitals in tbilisi,georgia.Georgian Med News. 2018 Jul-Aug;(280-281):164-168. [PubMed: 30204118]
Esposito EP, Cervoni M, Bernardo M, Crivaro V, Cuccurullo S, Imperi F, Zarrilli R. Molecular Epidemiology and Virulence Profiles of Colistin-Resistant Klebsiella pneumoniae Blood Isolates From the Hospital Agency "OspedaledeiColli," Naples, Italy. Front Microbiol. 2018;9:1463. [PMC free article: PMC6054975] [PubMed: 30061868]
Walter J, Haller S, Quinten C, Kärki T, Zacher B, Eckmanns T, Abu Sin M, Plachouras D, Kinross P, Suetens C, EcdcPps Study Group Healthcare-associated pneumonia in acute care hospitals in European Union/European Economic Area countries: an analysis of data from a point prevalence survey, 2011 to 2012. Euro Surveill. 2018 Aug;23(32) [PMC free article: PMC6092912] [PubMed: 30107871]
Para RA, Fomda BA, Jan RA, Shah S, Koul PA. Microbial etiology in hospitalized North Indian adults with community-acquired pneumonia. Lung India. 2018 Mar-Apr;35(2):108-115. [PMC free article: PMC5846258] [PubMed: 29487244]
Ergul AB, Cetin S, Altintop YA, Bozdemir SE, Ozcan A, Altug U, Samsa H, Torun YA. Evaluation of Microorganisms Causing Ventilator-Associated Pneumonia in a Pediatric Intensive Care Unit. Eurasian J Med. 2017 Jun;49(2):87-91. [PMC free article: PMC5469850] [PubMed: 28638248]
Liu C, Guo J. Characteristics of ventilator-associated pneumonia due to hypervirulent Klebsiella pneumoniae genotype in genetic background for the elderly in two tertiary hospitals in China. Antimicrob Resist Infect Control. 2018;7:95. [PMC free article: PMC6091109] [PubMed: 30128143]
Mitharwal SM, Yaddanapudi S, Bhardwaj N, Gautam V, Biswal M, Yaddanapudi L. Intensive care unit-acquired infections in a tertiary care hospital: An epidemiologic survey and influence on patient outcomes. Am J Infect Control. 2016 Jul 01;44(7):e113-7. [PubMed: 26944004]
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506. doi: 10.1016/S0140-6736(20)3018.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
Terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
