Morinaga Oleifera loaded niosomes for healing application: Arthritis
DOI:
https://doi.org/10.63682/jns.v14i24S.5931Keywords:
Biopesticides, Management, Potato, VirusesAbstract
The study aimed to evaluate the potential anti-arthritic properties of Moringa Oleifera leaf extract loaded into niosomes. The extract was obtained using the Soxhlet method with various solvents, and the best extract was determined based on its yield. The niosomes were prepared using the Ether Injection Method and incorporated into a gel. The effectiveness of the treatment was tested on rats with induced arthritis through various methods such as paw edema, body weight gain, arthritic index, haematology profile, and Eddy’s hot plate thermal analgesia method. The results indicated a positive response to the Moringa Oleifera treatment against arthritis. The niosomes were also evaluated for their size and shape and underwent gel permeation testing using a Franz diffusion cell. However, further research is necessary to confirm the effectiveness of the treatment in humans.
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Ghafelehbashi R, Akbarzadeh I, Tavakkoli Yaraki M, Lajevardi A, Fatemizadeh M, Heidarpoor Saremi L. Preparation, physicochemical properties, in vitro evaluation and release behavior of cephalexin-loaded niosomes. International Journal of Pharmaceutics. 2019;569(May):118580. Available from: https://doi.org/10.1016/ j.ijpharm.2019.118580.
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Z. Sezgin-Bayindir, A. Onay-Besikci, N. Vural, N. Yuksel, Niosomes encapsulating paclitaxel for oral bioavailability enhancement: Preparation, characterization, pharmacokinetics and biodistribution, J. Microencapsul. 30 (8) (2013) 796–804, https://doi.org/10.3109/02652048.2013.788088.
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