Treatment of melasma with oral administration of Tranexamic acid in patients at tertiary care center in kulasekharam, Kanyakumari, Tamil Nadu, India

Authors

  • Reshma J. A.
  • A. J.S Pravin

Keywords:

Melanocyte Activity, Skin Hyperpigmentation, South Indian Women, Pigmentation Disorders, Tranexamic Acid (TA), Melasma

Abstract

Melasma, a chronic pigmentary disorder, is prevalent among women, particularly in South India, where environmental and cultural factors contribute to its occurrence. This study evaluates the efficacy and safety of oral tranexamic acid (TA) in treating melasma in patients at Sree Mookambika  Hospital, Kulasekharam, Kanyakumari, Tamil Nadu. Fifty patients were enrolled and administered 250 mg of TA twice daily for six months. Results showed significant improvement, with over 90% of participants experiencing pigmentation reduction. Mild side effects were reported in 10% of cases, and the recurrence rate was 12%. These findings highlight oral TA as an effective treatment option, with implications for tailored strategies in South Indian populations

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Published

2025-05-07

How to Cite

1.
J. A. R, J.S Pravin A. Treatment of melasma with oral administration of Tranexamic acid in patients at tertiary care center in kulasekharam, Kanyakumari, Tamil Nadu, India. J Neonatal Surg [Internet]. 2025 May 7 [cited 2026 Apr. 1];14(21S):389-92. Available from: https://jneonatalsurg.com/index.php/jns/article/view/5297

Issue

Vol. 14 No. 21S (2025): Journal of Neonatal Surgery

Section

Original Article

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