Study The Effect of Nano-Flavonoid and Flavonoid Compounds Extraction from Bacopa Monnieri L. On The Serratia Marcescens

Authors

  • Maysam I. A. Al-Hassany
  • Bushra M. J. Alwash

Keywords:

Serratia marcescens, Bacopa monnieri L, Flavonoid, Nanoparticles, biofilm

Abstract

This study aimed to explore whether extract flavonoid and nano flavonoids can function as an anti-biofilm agent produced by Serratia marcescens . Firstly, flavonoid extraction from the Bacopa monnieri L.  and identification by using High Performance Liquid Chromatographic (HPLC) then used casein to manufacture flavonoid-casein nanoparticles by ultrasound method . Several techniques have been used to determine the chemical and physical properties of nanoparticles such as Scanning Electron Microscope (SEM)  and Zeta–Potential . S. marcescens isolates were collected and identified by culturing on Blood agar and MacConkey agar medium and confirmed by VITEK 2 system . Flavonoid and nano-flavonoids showed remarkable biofilm inhibitory effect on isolates of multidrug resistant S. marcescens . Strong biofilm producer strains show weak biofilm production After incubation for 24 hours at 37Co with MIC concentration of flavonoid and nano flavonoids

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Published

2025-04-30

How to Cite

1.
Al-Hassany MIA, J. Alwash BM. Study The Effect of Nano-Flavonoid and Flavonoid Compounds Extraction from Bacopa Monnieri L. On The Serratia Marcescens. J Neonatal Surg [Internet]. 2025Apr.30 [cited 2025Sep.21];14(20S):82-90. Available from: https://jneonatalsurg.com/index.php/jns/article/view/4921

Issue

Vol. 14 No. 20S (2025): Journal of Neonatal Surgery

Section

Original Article

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