Development Of Novel Protective Strategies For Riga-Fede Disease In Infants A Clinical Trial
DOI:
https://doi.org/10.52783/jns.v14.3616Keywords:
Riga-Fede disease, oral trauma, protective oral appliances, bioadhesive gels, clinical trialAbstract
Riga-Fede disease (RFD) is a rare traumatic ulcerative condition observed in infants, typically caused by repetitive friction of the tongue or oral mucosa against natal or neonatal teeth. The present study aims to develop novel protective strategies to prevent and manage RFD through clinical intervention. A prospective clinical trial was conducted on infants diagnosed with RFD to evaluate the efficacy of customized protective oral appliances, bioadhesive gels, and modified feeding techniques in minimizing trauma and promoting ulcer healing. The study included infants aged 3 to 12 months with confirmed RFD. The primary outcomes assessed were reduction in ulcer size, pain relief, and overall healing time. Results indicated that the application of bioadhesive gels combined with a protective oral appliance significantly reduced ulcer progression and improved healing outcomes compared to conventional treatment. The findings highlight the potential of these novel strategies in enhancing the management of RFD and preventing recurrence. Future research should focus on long-term follow-up and further refinement of these protective measures to optimize patient outcomes.
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Cunha R. F., Boer F. A. C., Torriani D. D., Frossard W. T. G. Natal and neonatal teeth: review of the literature. Pediatric Dentistry. 2001;23(2):158–162.
Leung A. K., Robson W. R. Natalteeth: a review. Journal of the National Medical Association. 2006;98(2):226–228.
Farsi J. D., Ahmed M. M. Natal and neonatal teeth. Saudi Medical Journal. 2014;35:499–503.
Mhaske S., Yuwanati M. B., Mhaske A., Ragavendra R., Kamath K., Saawarn S. Natal and neonatal teeth: an overview of the literature. ISRN Pediatrics. 2013;2013:11. doi: 10.1155/2013/956269.956269
Campos-Muñoz L., Quesada-Cortés A., Corral-De La Calle M., et al. Tongue ulcer in a child: Riga-Fede disease. Journal of the European Academy of Dermatology and Venereology. 2006;20(10):1357–1359. doi: 10.1111/j.1468-3083.2006.01715.x.
Slayton R. L. Treatment alternatives for sublingual traumatic ulceration (Riga-Fede disease) Pediatric Dentistry. 2000;22(5):413–414.
Costacurta M., Maturo P., Docimo R. Riga-Fede disease and neonatal teeth. Oral Implantology. 2012;5(1):26–30.
Deep S. B., Ranadheer E., Rohan B. Riga-Fede disease: report of a case with literature review. Journal of Academy of Advanced Dental Research. 2011;2(2):27–30.
Rao R. S., Mathad S. V. Natal teeth: case report and review of literature. Journal of Oral and Maxillofacial Pathology. 2009;13:41–46. doi: 10.4103/0973-029X.44574.
10.Liu M.-H., Huang W.-H. Oral abnormalities in Taiwanese newborns. Journal of Dentistry for Children. 2004;71(2):118–120.
Wollina U. Riga-Fede-like disease in a 70 year old woman. Indian Journal of Dermatology. 2010;55(1):92–94. doi: 10.4103/0019-5154.60361.
Mohan R. P. S., Verma S., Gill N., Singh U. Riga-fede disease (Cardarelli's aphthae): a report of nine cases. South African Journal of Child Health. 2014;8(2):72–74. doi: 10.7196/sajch.636.
van der Meij E. H., de Vries T. W., Eggink H. F., de Visscher J. G. A. M. Traumatic lingual ulceration in a newborn: riga-fede disease. Italian Journal of Pediatrics. 2012;38(1, article 20) doi: 10.1186/1824-7288-38-20.
Choi S. C., Park J. H., Choi Y. C., Kim G.-T. Sublingual traumatic ulceration (a Riga-Fede disease): report of two cases. Dental Traumatology. 2009;25(3):e48–e50. doi: 10.1111/j.1600-9657.2009.00773.x.
Singh S., Subbareddy V. V., Dhananjaya G., Patil R. Reactive fibrous hyperplasia associated with a natal tooth: case report. Journal of Indian Society of Pedodontics and Preventive Dentistry. 2004;22(4):183–186.
Prabhakar M., Kaur M. S. Prosthetic replacement options for premature loss of deciduous anterior teeth: case report. Indian Journal of Dental Research. 2014;4(6):55–57.
Ulson R. C. B., Correa M. S. N. P., Lopes L. D. Dente neonatal: relato de caso clínico. Revista do Instituto de Ciências da Saúde. 2008;26(1):130–134.
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