Decoding FIGO Staging In Postmenopausal Endometrial Cancer: A Window Into Prognosis

Abstract

Background: Endometrial carcinoma (EC) is a common malignancy of the uterus, predominantly affecting
postmenopausal women. This case series examines three cases of endometrial carcinoma in menopausal women, with a
focus on the correlation between clinical findings, FIGO staging, and histopathological results from endometrial biopsy
and hysterectomy specimens.
Cases: The first patient, a 56-year-old woman, had postmenopausal bleeding and was diagnosed with endometrioid
endometrial carcinoma, FIGO grade II. The second patient, a 63-year-old woman, also presented with abnormal bleeding
and was diagnosed with Papillary serous endometrial carcinoma, FIGO grade II. The third patient, a 64-year-old woman,
presented with postmenopausal bleeding and was diagnosed with endometrioid endometrial carcinoma, FIGO grade I.
Patients underwent surgical management, and the final histopathological diagnosis correlated with the preoperative
findings.
Conclusion: Endometrial biopsy played a crucial role in initial diagnosis and guided the staging process, but hysterectomy
and subsequent pathological examination provided definitive staging. The correlation between FIGO staging, clinical
presentation, and histopathological findings reinforced the significance of early diagnosis and intervention in improving
patient outcomes. This case series highlights the importance of comprehensive evaluation, including clinical assessment,
imaging, biopsy, and surgical management, for accurate diagnosis and staging of endometrial carcinoma in menopausal
women.