Intraocular Pressure and Central Corneal Thickness in Premature and Full Term Newborns in Tertiary Health Care Centre Rural India
DOI:
https://doi.org/10.52783/jns.v14.2079Keywords:
central corneal thickness, full term, intraocular pressure, newborn, premature, retinopathyAbstract
Introduction- Central corneal thickness (CCT) and Introocular pressure (IOP) measurement plays an important role in diagnosis and treatment of various eye disorders. The aim of this study was to assess the correlation between central corneal thickness (CCT) and intraocular pressure (IOP) in both preterm and full-term babies. Additionally, the study aimed to compare the differences in IOP and CCT between premature and full-term newborns.
Material and methods- The present prospective observational study was conducted at pediatric ward and NICU of Pediatric department at a tertiary care hospital among 50 premature and full-term newborns during the study period of one year. Patients were divided into two groups i.e. group A and group B. Group A consist of premature newborn (gestational age<37 weeks) and Group B consist of fullterm newborn (gestational age>.37 week). Cases were selected on the basis of following inclusion and exclusion criteria. The mean values of intraocular pressure (IOP) and central corneal thickness (CCT) were compared using a one-way analysis of variance (ANOVA) test. A P value > 0.05 was considered statistically significant.
Results– Out of 50 cases 29 were premature and 21 were full term newborn. The mean age at measurement was 33 ± 2.1 and 38 ± 2 weeks and the comparison was statistically significant. The mean birth-weight was 1578±324 (grams ) in pre mature and 2897±456 in full term (grams). The mean intraocular pressure (IOP) was 19.2 ± 3.3 mm Hg in premature newborns and 17.1 ± 2.4 mm Hg in full-term newborns. A t-test analysis showed a significant difference between the two groups (P = 0.001). The mean corneal curvature thickness (CCT) was 589 ± 35 mm in premature newborns and 568 ± 25 mm in full-term newborns
Conclusion– IOP readings in premature babies were somewhat higher compared to full-term newborns due to an elevated CCT (central corneal thickness).
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