The Impact of Personalized Dialysis Prescription on Clinical Outcomes in Maintenance Hemodialysis Patients: A Randomized Controlled Trial

Abstract

Background: The research evaluates if individualized dialysis prescriptions can boost clinical results for people who require maintenance hemodialysis while examining their effects on survival rates and arrhythmogenic events and blood pressure regulation alongside electrolyte balance.

Methods: A randomized controlled trial involving 120 patients under maintenance hemodialysis included them. Two separate dialysis groupings with sixty participants were formed which included standard dialysis and personalized dialysis. Each patient received individualized dialysis prescriptions which took into account their electrolyte concentrations and health conditions in the personalized group. Research measured mortality and arrhythmia events and blood pressure and electrolyte changes before and after six months of the study period.

Results: Results showed that the personalized dialysis treatment performance surpassed those of standard dialysis. The personalized dialysis group recorded better health results with fewer mortalities combined with fewer arrhythmia events and improved blood pressure control and more stable potassium and magnesium serum levels. Fluid balance in the personalized dialysis approach was better while the number of fluid overload cases remained lower.

Conclusions: Medical care for patients under hemodialysis treatment substantially improved through customized dialysis prescriptions. In patients with haemodialysis, personalized therapy, based upon individual needs is increasingly effective while minimizing complications with the general patient's well-being. Such discoveries help to adopt personalization procedures into routine medical practice for achieving optimized dialysis treatment.