Esophageal stricture as a complication in post operative neonates with congenital esophageal atresia with tracheoesophageal fistula
DOI:
https://doi.org/10.52783/jns.v14.1604Keywords:
Esophageal Atresia, Esophageal stricture, Neonate, Tracheoesophageal fistulaAbstract
Introduction: Esophageal Atresia (EA) with Tracheoesophageal fistula (TOF) is one of the commonest congenital anomalies encountered in the pediatric surgery with commonest postoperative complication as esophageal stricture (ES) and gastroesophageal reflux disease (GERD). The aim of this study was to identify factors associated with ES formation in EA with TOF during post operative period.
Materials and Methods: This cross-sectional study was carried out in pediatrics surgery department. A total 30 neonates with EA with TOF who were diagnosed clinically and radiologically were included while pure atresia cases were excluded. The distance between upper and lower esophageal pouch was noted with ruler intraoperatively. Post operative soluble contrast dye study was done to detect leaks. If no was leak present then ratio of upper and lower esophageal pouch width (UPW: LPW) was measured. During follow up, ES and GERD were diagnosed clinically and radiologically. The data was analyzed using MS-Excel and SPSS software and p value < 0.5 was taken as significant.
Results: The measurement of gap between upper & lower pouch was < 2cms and >2cms in 12(40%) and 18(60%) patients respectively. The ES was found in 9(30%), GERD in 1(3.3%) and both ES and GERD in 6(20%) patients. The ratio of UPW: LPW found to be more than 1.5, equal to 1.5 and less than 1.5 in 12,2 and 1 patient respectively with ES. Dilatation for ES was required in all those with UPW: LPW >1.5 which was statistically significant. The postoperative UPW:LPW ratio showed statistically significant correlation with the intraoperative gap between upper & lower pouch and anastomosis under tension.
Conclusion: The ES had significant correlation with gap between upper & lower esophageal pouch more than 2 cm and anastomosis under tension. The ratio of UPW: LPW ≥1.5 needed dilatation for ES during follow up.
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References
Puri P. Esophageal atresia and tracheoesophageal fistula. In: Newborn Surgery.3rd ed. CRC Press; 2011:387.
Friedmacher F, Kroneis B, Huber-Zeyringer A. Postoperative Complications and Functional Outcome after Esophageal Atresia Repair: Results from Longitudinal Single-Center Follow-Up. J Gastrointest Surg. 2017;21(6):927-35. doi:10.1007/s11605-017-3423-0
Thompson A, Thakkar H, Khan H, Yardley IE. Not all neonates with oesophageal atresia and tracheoesophageal fistula are a surgical emergency. J Pediatr Surg. 2019;54(2):244-46. doi:10.1016/j. jpedsurg.2018.10.074
Masuya R. Predictive factors affecting the prognosis and late complications of 73 consecutive cases of esophageal atresia at 2 centers. Pediatric Surgery International. https://doi.org/10.1007/s00383-018-4326-1
Zani A, Wolinska J, Cobellis G, Chiu PP, Pierro A. Outcome of esophageal atresia/tracheoesophageal fistula in extremely low birth weight neonates (<1000 grams). Pediatr Surg Int. 2016;32(1):83-88. doi:10.1007/s00383-015-3816-7
Coran AG, Adzick NS, Krummel TM, Laberge JM, Shamberger RC, Caldamone AA. Congenital anomalies of the Esophagus. In: Pediatric Surgery. Vol.2. 7th ed. 893.
C Harmon C M, Arnold G. Direct aspiration of secretions into the trachea may occur with either a proximal or a distal tracheoesophageal fistula. Journal of Pediatric Surgery.1997;32(10):1401-1529
Losty P D, Baillie Colin. Esophageal Atresia and trachea-esophageal fistula. In Newborn surgery, 2nd edition,2023:337-352
Thakkar HS, Cooney J, Kumar N, Kiely E. Measured gap length and outcomes in oesophageal atresia. J Pediatr Surg. 2014;49(9):1343-46. doi:10.1016/j.jpedsurg.2014.03.021
Singh A, Bajpai M, Bhatnagar V, Agarwala S, Srinivas M, Sharma N. Effect of number of associated anomalies on outcome in esophageal atresia with or without tracheoesophageal fistula patient. Afr J Paediatr Surg. 2013;10(4):320-322. doi:10.4103/0189-6725.125430
Acher CW, Ostlie DJ, Leys CM, Struckmeyer S, Parker M, Nichol PF. Long-Term Outcomes of Patients with Tracheoesophageal Fistula/Esophageal Atresia: Survey Results from Tracheoesophageal Fistula/Esophageal Atresia Online Communities. Eur J Pediatr Surg. 2016;26(6):476-480. doi:10.1055/s-0035-1570103
Bawa M, Menon P and K. L. N. Rao. Role of feeding jejunostomy in major anastomotic disruptions in esophageal atresia: A pilot study. Journal of Indian Association of Pediatric Surgeons.
Allin B, Knight M, Johnson P, Burge D; BAPS-CASS. Outcomes at one-year post anastomosis from a national cohort of infants with esophageal atresia. PLOS One. 2014;9(8):e106149. Published 2014 Aug 25. doi:10.1371/ journal. pone. 0106149
Okata Y, Maeda K, Bitoh Y, et al. Evaluation of the intraoperative risk factors for esophageal anastomotic complications after primary repair of esophageal atresia with tracheoesophageal fistula. Pediatr Surg Int. 2016;32(9):869-73. doi:10.1007/s00383-016-3931-0
Davidson JR et al. Pediatric Esophageal Dilatations: A Cross-Speciality Experience. Journal of Laparoendoscopic & Advanced Surgical Techniques. DOI: 10.1089/lap.2019.0592
D. Lévesque, R. Baird, J.-M. Laberge; Refractory strictures post-esophageal atresia repair: what are the alternatives? Diseases of the Esophagus, Volume 26, Issue 4, 1 May 2013, Pages 382–387, https://doi.org/10.1111/dote.12047
Leibovitch L, Zohar I, Maayan-Mazger A, Mazkereth R, Strauss T, Bilik R. Infants Born with Esophageal Atresia with or without Tracheo-Esophageal Fistula: Short- and Long-Term Outcomes. Isr Med Assoc J. 2018;20(3):161-166.
Allin B, Knight M, Johnson P, Burge D; BAPS-CASS. Outcome at one-year post anastomosis from a national cohort of infants with esophageal atresia. PLOS One. 2014;9(8): e106149. Published 2014 Aug 25. doi:10.1371/ journal. pone. 0106149
Landisch RM, Foster S, Gregg D, et al. Utilizing stricture indices to predict dilation of strictures after esophageal atresia repair. J Surg Res. 2017; 216:172-78. doi:10.1016/ j.jss.2017.04.024
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