A systematic review and meta-analysis of the prevalence of medication errors in hospitalized pediatric patients
Keywords:
Medication errors, pediatric patients, hospital, reviewAbstract
Medication Errors (MEs) are likely elevated in Pediatric Hospital (PH) environments. Estimations about the prevalence of MEs have failed to consider the variability in recognizing MEs methodologies and criteria among research, contextual disparities within wards, and the utilization of computerized versus prescription records. The objective was to perform a Systematic Review (SR) and Meta-Analysis (MA) to yield distinct predictions of the incidence of MEs among Pediatric Inpatients (PIP), categorized by hospital wards, and the utilization of electronic versus paper medicine charts while considering variations in recognizing MEs methodologies and explanations. The research systematically searched five databases to uncover research that evaluated ME rates by pharmaceutical chart audits, personal observation, or a combination of methods. The research found 70 studies, 20 of which were about PH utilizing electronic charts. Most research evaluated MEs, while only a limited number examined MEs in administration. Research on PH utilizing electronic charts typically indicated fewer MEs than those employing paper records, albeit with occasional discrepancies. MEs identification techniques influenced the frequency of MEs across the wards; no additional differences were observed. The definition of MEs did not consistently influence claimed ME rates. MEs frequently occur in PHs, especially in intensive care and emergency rooms. Hospitals utilizing electronic charts exhibited a reduced incidence of MEs compared to manual charts. Future research utilizing controlled settings is necessary to ascertain the actual effects of electronic records and other treatments on MEs and related damage in hospitals.
Downloads
Metrics
References
Laatikainen O, Sneck S, Turpeinen M. Medication-related adverse events in health care—what have we learned? A narrative overview of the current knowledge. European journal of clinical pharmacology. 2022 Feb 1:1-2. https://doi.org/10.1007/s00228-021-03213-x
Ramachandran S. Comparative Analysis of Antibiotic Use and Resistance Patterns in Hospitalized Patients. Clinical Journal for Medicine, Health and Pharmacy. 2023 Oct 9;1(1):73-82.
Somani R, Muntaner C, Hillan E, Velonis AJ, Smith P. A systematic review: effectiveness of interventions to de-escalate workplace violence against nurses in healthcare settings. Safety and health at work. 2021 Sep 1;12(3):289-95. https://doi.org/10.1016/j.shaw.2021.04.004
Jara AJ, Zamora MA, Skarmeta AF. Intra-mobility for hospital wireless sensor networks based on 6LoWPAN. In2010 6th International Conference on Wireless and Mobile Communications 2010 Sep 20 (pp. 389-394). IEEE. https://doi.org/10.1109/ICWMC.2010.54
Vanan JT, Manalan J, Soundrarajan DJ, Raja T. Awareness and Utilization of Electronic Resources among Junior Research Fellows with Special Reference to Christian Medical College & Hospital, Vellore, Tamil Nadu. Indian Journal of Information Sources and Services. 2019;9(S1):32-6. https://doi.org/10.51983/ijiss.2019.9.S1.569
Mei F, Chen F, Hu K, Gao Q, Zhao L, Shang Y, Zhao B, Ma B. Registration and reporting quality of systematic reviews on surgical intervention: A meta-epidemiological study. journal of surgical research. 2022 Sep 1;277: 200-10. https://doi.org/10.1016/j.jss.2022.04.026
Surendar A. Internet of Medical Things (IoMT): Challenges and innovations in embedded system design. SCCTS J Embed Syst Des Appl. 2024;1(1):33-36.
Dhage PC, Thakker RA, Warhade KK. Security mechanism in MAMATA healthcare system using rule-based algorithm for maternal hospitals and pathology laboratories. J Internet Serv Inf Secur. 2024;14(4):292-311. https://doi.org/10.58346/JISIS.2024.I4.018
Kuitunen S, Saksa M, Tuomisto J, Holmström AR. Medication errors related to high-alert medications in a paediatric university hospital–a cross-sectional study analysing error reporting system data. BMC pediatrics. 2023 Oct 31;23(1):548. https://doi.org/10.1186/s12887-023-04333-2
Veerappan S. Digital management and sustainable competitiveness: Using eco-innovation and green absorptive capacity in travel and hospitality enterprises. Glob Perspect Manag. 2024;2(3):32-43.
Henry Basil J, Premakumar CM, Mhd Ali A, Mohd Tahir NA, Mohamed Shah N. Prevalence, causes and severity of medication administration errors in the neonatal intensive care unit: a systematic review and meta-analysis. Drug Safety. 2022 Dec;45(12):1457-76. https://doi.org/10.1007/s40264-022-01236-6
Jobson MC, Subhashini R. To Assess the Social Maturity Level among Congenital Heart Defect Children. Sciences. 2016;3(2):1-6.
Kumar TMS. Integrative approaches in bioinformatics: Enhancing data analysis and interpretation. Innov Rev Eng Sci. 2024;1(1):30-33.
Yamamoto R, Sato Y, Maeshima K, Tomita K, Takemura R, Katsura M, Kondo Y, Yasuda H, Kushimoto S, Sasaki J. Pediatric blunt liver and spleen injury treated in hospitals with pediatric intensive care units: Post-hoc analysis of a multicenter, retrospective observational study. Journal of Pediatric Surgery. 2025 Mar 1;60(3):162106. https://doi.org/10.1016/j.jpedsurg.2024.162106
Khudhur OI, Aziz AA. Determination of radon concentrations in selected soil samples from the city of Mosul using nuclear track detector CR-39. Int Acad J Sci Eng. 2024;11(1):169-173. https://doi.org/10.9756/IAJSE/V11I1/IAJSE1120
dos Santos Alcântara T, Carvalho GA, Sanchez JM, Ramos SF, Cunha LC, de Castro Araújo-Neto F, Valença-Feitosa F, Silvestre CC, de Lyra Junior DP. Quality indicators of hospitalized children influenced by clinical pharmacist services: a systematic review. Research in Social and Administrative Pharmacy. 2023 Oct 1;19(10):1315-30. https://doi.org/10.1016/j.sapharm.2023.07.003
Boopathy EV, Shanmugasundaram M, Vadivu NS, Karthikkumar S, Diban R, Hariharan P, Madhan A. Lorawan based coalminers rescue and health monitoring system using IOT. Archives for Technical Sciences. 2024 Dec 24;2(31):213-9. https://doi.org/10.70102/afts.2024.1631.213
Belagodu Sridhar S, Karattuthodi MS, Parakkal SA. Role of artificial intelligence in clinical and hospital pharmacy. InApplication of Artificial Intelligence in Neurological Disorders 2024 Jul 1 (pp. 229-259). Singapore: Springer Nature Singapore. https://doi.org/10.1007/978-981-97-2577-9_12
Downloads
Published
How to Cite
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
Terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.