A systematic review and meta-analysis of the prevalence of medication errors in hospitalized pediatric patients

Authors

  • Sanjay Kumar Mire
  • Kishor Kumar Sahu

Keywords:

Medication errors, pediatric patients, hospital, review

Abstract

Medication Errors (MEs) are likely elevated in Pediatric Hospital (PH) environments. Estimations about the prevalence of MEs have failed to consider the variability in recognizing MEs methodologies and criteria among research, contextual disparities within wards, and the utilization of computerized versus prescription records. The objective was to perform a Systematic Review (SR) and Meta-Analysis (MA) to yield distinct predictions of the incidence of MEs among Pediatric Inpatients (PIP), categorized by hospital wards, and the utilization of electronic versus paper medicine charts while considering variations in recognizing MEs methodologies and explanations. The research systematically searched five databases to uncover research that evaluated ME rates by pharmaceutical chart audits, personal observation, or a combination of methods. The research found 70 studies, 20 of which were about PH utilizing electronic charts. Most research evaluated MEs, while only a limited number examined MEs in administration. Research on PH utilizing electronic charts typically indicated fewer MEs than those employing paper records, albeit with occasional discrepancies. MEs identification techniques influenced the frequency of MEs across the wards; no additional differences were observed. The definition of MEs did not consistently influence claimed ME rates. MEs frequently occur in PHs, especially in intensive care and emergency rooms. Hospitals utilizing electronic charts exhibited a reduced incidence of MEs compared to manual charts. Future research utilizing controlled settings is necessary to ascertain the actual effects of electronic records and other treatments on MEs and related damage in hospitals.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Laatikainen O, Sneck S, Turpeinen M. Medication-related adverse events in health care—what have we learned? A narrative overview of the current knowledge. European journal of clinical pharmacology. 2022 Feb 1:1-2. https://doi.org/10.1007/s00228-021-03213-x

Ramachandran S. Comparative Analysis of Antibiotic Use and Resistance Patterns in Hospitalized Patients. Clinical Journal for Medicine, Health and Pharmacy. 2023 Oct 9;1(1):73-82.

Somani R, Muntaner C, Hillan E, Velonis AJ, Smith P. A systematic review: effectiveness of interventions to de-escalate workplace violence against nurses in healthcare settings. Safety and health at work. 2021 Sep 1;12(3):289-95. https://doi.org/10.1016/j.shaw.2021.04.004

Jara AJ, Zamora MA, Skarmeta AF. Intra-mobility for hospital wireless sensor networks based on 6LoWPAN. In2010 6th International Conference on Wireless and Mobile Communications 2010 Sep 20 (pp. 389-394). IEEE. https://doi.org/10.1109/ICWMC.2010.54

Vanan JT, Manalan J, Soundrarajan DJ, Raja T. Awareness and Utilization of Electronic Resources among Junior Research Fellows with Special Reference to Christian Medical College & Hospital, Vellore, Tamil Nadu. Indian Journal of Information Sources and Services. 2019;9(S1):32-6. https://doi.org/10.51983/ijiss.2019.9.S1.569

Mei F, Chen F, Hu K, Gao Q, Zhao L, Shang Y, Zhao B, Ma B. Registration and reporting quality of systematic reviews on surgical intervention: A meta-epidemiological study. journal of surgical research. 2022 Sep 1;277: 200-10. https://doi.org/10.1016/j.jss.2022.04.026

Surendar A. Internet of Medical Things (IoMT): Challenges and innovations in embedded system design. SCCTS J Embed Syst Des Appl. 2024;1(1):33-36.

Dhage PC, Thakker RA, Warhade KK. Security mechanism in MAMATA healthcare system using rule-based algorithm for maternal hospitals and pathology laboratories. J Internet Serv Inf Secur. 2024;14(4):292-311. https://doi.org/10.58346/JISIS.2024.I4.018

Kuitunen S, Saksa M, Tuomisto J, Holmström AR. Medication errors related to high-alert medications in a paediatric university hospital–a cross-sectional study analysing error reporting system data. BMC pediatrics. 2023 Oct 31;23(1):548. https://doi.org/10.1186/s12887-023-04333-2

Veerappan S. Digital management and sustainable competitiveness: Using eco-innovation and green absorptive capacity in travel and hospitality enterprises. Glob Perspect Manag. 2024;2(3):32-43.

Henry Basil J, Premakumar CM, Mhd Ali A, Mohd Tahir NA, Mohamed Shah N. Prevalence, causes and severity of medication administration errors in the neonatal intensive care unit: a systematic review and meta-analysis. Drug Safety. 2022 Dec;45(12):1457-76. https://doi.org/10.1007/s40264-022-01236-6

Jobson MC, Subhashini R. To Assess the Social Maturity Level among Congenital Heart Defect Children. Sciences. 2016;3(2):1-6.

Kumar TMS. Integrative approaches in bioinformatics: Enhancing data analysis and interpretation. Innov Rev Eng Sci. 2024;1(1):30-33.

Yamamoto R, Sato Y, Maeshima K, Tomita K, Takemura R, Katsura M, Kondo Y, Yasuda H, Kushimoto S, Sasaki J. Pediatric blunt liver and spleen injury treated in hospitals with pediatric intensive care units: Post-hoc analysis of a multicenter, retrospective observational study. Journal of Pediatric Surgery. 2025 Mar 1;60(3):162106. https://doi.org/10.1016/j.jpedsurg.2024.162106

Khudhur OI, Aziz AA. Determination of radon concentrations in selected soil samples from the city of Mosul using nuclear track detector CR-39. Int Acad J Sci Eng. 2024;11(1):169-173. https://doi.org/10.9756/IAJSE/V11I1/IAJSE1120

dos Santos Alcântara T, Carvalho GA, Sanchez JM, Ramos SF, Cunha LC, de Castro Araújo-Neto F, Valença-Feitosa F, Silvestre CC, de Lyra Junior DP. Quality indicators of hospitalized children influenced by clinical pharmacist services: a systematic review. Research in Social and Administrative Pharmacy. 2023 Oct 1;19(10):1315-30. https://doi.org/10.1016/j.sapharm.2023.07.003

Boopathy EV, Shanmugasundaram M, Vadivu NS, Karthikkumar S, Diban R, Hariharan P, Madhan A. Lorawan based coalminers rescue and health monitoring system using IOT. Archives for Technical Sciences. 2024 Dec 24;2(31):213-9. https://doi.org/10.70102/afts.2024.1631.213

Belagodu Sridhar S, Karattuthodi MS, Parakkal SA. Role of artificial intelligence in clinical and hospital pharmacy. InApplication of Artificial Intelligence in Neurological Disorders 2024 Jul 1 (pp. 229-259). Singapore: Springer Nature Singapore. https://doi.org/10.1007/978-981-97-2577-9_12

Downloads

Published

2025-01-28

How to Cite

1.
Kumar Mire S, Kumar Sahu K. A systematic review and meta-analysis of the prevalence of medication errors in hospitalized pediatric patients. J Neonatal Surg [Internet]. 2025Jan.28 [cited 2025Feb.14];14(1S):41-9. Available from: https://jneonatalsurg.com/index.php/jns/article/view/1493

Most read articles by the same author(s)