Pharmacist‑Based Interventions Analysis to Reduce Drug-Related Problems for Surgery Patients
Keywords:
Pharmacy, drug-related problems, surgery, interventionsAbstract
The misuse of drugs is detrimental and prevalent among hospitalized patients. Patients admitted to general surgery wards typically face a significant risk of Drug-Related Problems (DRPs). This Randomized Controlling Trails (RCT) sought to evaluate the efficacy of a healthcare program on surgical wards for identifying and mitigating DRPs compared to regular healthcare. This research was performed in standard surgical wards encompassing gastrointestinal, arterial, and orthopedic procedures at a central teaching facility for six months. Enrolled participants were randomized into treatment or controlling categories. Medical pharmacists evaluated participants’ DRPs and proposed solutions to address the detected DRPs in the treatment category.
The treatment category (n=75) and the controlling category (n=70) had an average age of 58.5 years, with 53.0% of participants being female. 1100 DRPs were detected, averaging 9.2 per participant (intervention category, 9.1 ± 3.5; control category, 9.5 ± 3.5). The often recognized DRPs comprised concerns about safety (25.4%) and effectiveness (18.5%). The adoption rate of pharmacists' suggestions by doctors was notably high at 95%, accompanied by a DRP corrective rate of 60.5% throughout hospitalization. The efficacy of pharmacological care was demonstrated by attaining medical goals and preventing mortality, achieving 69.3% in the treatment category, in contrast to 20.4% in the controlling category (p<0.001). This research demonstrates that DRPs are prevalent amongst surgery recipients, particularly concerning drug effectiveness and safety. Pharmacists' suggestions significantly aided in addressing the majority of reported DRPs and enhanced medication management for general surgical participants
Downloads
Metrics
References
Schmelzer KP, Liebetrau D, Kämmerer W, Meisinger C, Hyhlik-Dürr A. Strategies for avoiding typical drug–drug interactions and drug-related problems in patients with vascular diseases. Medicina. 2023 Apr 17;59(4):780. https://doi.org/10.3390/medicina59040780
Chandra WR, Jayabal R. Scientometric study of the Indian Journal of Plastic Surgery. Indian J Inf Sources Serv. 2019;9(2):81-84. https://doi.org/10.51983/ijiss.2019.9.2.618
Alshaikhmubarak FQ, Keers RN, Lewis PJ. Potential risk factors of drug-related problems in hospital-based mental health units: a systematic review. Drug Safety. 2023 Jan;46(1):19-37. https://doi.org/10.1007/s40264-022-01249-1
Dhage PC, Thakker RA, Warhade KK. Security Mechanism in MAMATA Healthcare System Using Rule based Algorithm for Maternal Hospitals and Pathology Laboratories. https://doi.org/10.58346/JISIS.2024.I4.018
Bommakanti V, Puthenparambil Ajikumar A, Sivi CM, Prakash G, Mundanat AS, Ahmad F, Haque S, Prieto MA, Rana SS. An overview of herbal nutraceuticals, their extraction, formulation, therapeutic effects and potential toxicity. Separations. 2023 Mar 6;10(3):177. https://doi.org/10.3390/separations10030177
Seyedan SA. A study of the relationship between personality traits and internet addiction among secondary school male students in Torbat Heydarieh. Int Acad J Soc Sci. 2017;4(2):73-83.
Nayak A, Raghatate KS. Image segmentation and classification of aquatic plants using convolutional neural network. Int J Aquat Res Environ Stud. 2024;4(S1):14-19. https://doi.org/10.70102/IJARES/V4S1/3
Wang Y, Zhu J, Shan L, Wang C, Dong Z, Yang W, Chinese Obesity and Metabolic Surgery Collaborative. Drug-related problems in bariatric surgery: a retrospective Study. Obesity Surgery. 2022 Dec;32(12):3961-72. https://doi.org/10.1007/s11695-022-06295-3
Musa KM, Alshemary KKH. The role of nanoparticles in sunscreen: UV protection and particle size. Int Acad J Sci Eng. 2024;11(1):153-164. https://doi.org/10.9756/IAJSE/V11I1/IAJSE1118
Papadopoulos G, Christodoulou M. Design and Development of Data Driven Intelligent Predictive Maintenance for Predictive Maintenance. Association Journal of Interdisciplinary Technics in Engineering Mechanics. 2024 Jun 28;2(2):10-8.
Stenberg E, dos Reis Falcao LF, O’Kane M, Liem R, Pournaras DJ, Salminen P, Urman RD, Wadhwa A, Gustafsson UO, Thorell A. Guidelines for perioperative care in bariatric surgery: enhanced recovery after surgery (ERAS) society recommendations: a 2021 update. World journal of surgery. 2022 Apr;46(4):729-51. https://doi.org/10.1007/s00268-021-06394-9
Pandey U, Corbett G, Mohan S, Reagu S, Kumar S, Farrell T, Lindow S. Anxiety, depression and behavioural changes in junior doctors and medical students associated with the coronavirus pandemic: a cross-sectional survey. The Journal of Obstetrics and Gynecology of India. 2021 Feb;71:33-7. https://doi.org/10.1007/s13224-020-01366-w
Xie J, Huang X, Gao M, Wei L, Wang R, Chen J, Zeng Y, Ji B, Liu T, Wang J, Wu H. Surgical pharmacy for optimizing medication therapy management services within enhanced recovery after surgery (ERAS®) programs. Journal of Clinical Medicine. 2023 Jan 12;12(2):631. https://doi.org/10.3390/jcm12020631
Han Y, Chen J, Xu Y, Huang P, Hou L. Nurse-led medication management as a critical component of transitional care for preventing drug-related problems. Aging Clinical and Experimental Research. 2024 Jul 26;36(1):151. https://doi.org/10.1007/s40520-024-02799-3
Myoa Z, Pyo H, Mon M. Leveraging Real-World Evidence in Pharmacovigilance Reporting. Clinical Journal for Medicine, Health and Pharmacy. 2023 Oct 9;1(1):48-63.
Zhang W, Seong D. Using Artificial Intelligence to Strengthen the Interaction between Humans and Computers and Biosensor Cooperation. https://doi.org/10.58346/JOWUA.2024.I4.005
Venugopal RM. Efficient Hybrid CNN Method to Classify the Liver Diseases. Journal of Wireless Mobile Networks, Ubiquitous Computing, and Dependable Applications. 2023;14(3):36-47. https://doi.org/10.58346/JOWUA.2023.I3.004
Alkaim A, Hassan A. Incorporating training and management for institutional sustainability: the worldwide implementation of sustainable development goals. Glob Perspect Manag. 2024;2(4):26-35.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
Terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
