Congenital immature orbital teratoma with sarcomatous transformation presenting as exophthalmos: A case report

Authors

  • Gregório Andreassa Soares Faculdades Pequeno Príncipe, Liga Acadêmica de Patologia Oncológica Pequeno Príncipe.Curitiba-PR, Brazil
  • Samya Hamad Mehanna Department of Anatomical Pathology, Faculdades Pequeno Príncipe, Curitiba-PR, Brazila
  • Júlia Costa Linhares Department of Anatomical Pathology, Hospital Erasto Gaertner, Curitiba-PR, Brazil

DOI:

https://doi.org/10.47338/jns.v14.1403

Keywords:

Surgical oncology, Orbital neoplasms, Teratomas, Immature

Abstract

Background: Congenital immature orbital teratomas are rare neoplasms, with intraorbital cases presenting unique diagnostic and therapeutic challenges.
Case Presentation: This report presents a patient who has exhibited rapid-growing right exophthalmos since birth. Imaging studies revealed a progressively expanding lesion in the right orbital cavity and optic nerve. Following partial resection and subsequent orbital exenteration, histopathological and immunohistochemical analyses confirmed the diagnosis of immature teratoma with sarcomatous transformation. The patient underwent chemotherapy and remains under surveillance with no signs of disease recurrence.
Conclusion: This case highlights the complexities associated with diagnosing and treating rare orbital teratomas, contributing valuably to the existing literature.

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References

Tsoutsanis PA, Charonis GC. Congenital orbital teratoma: a case report with preservation of the globe and 18 years of follow-up. BMC Ophthalmol. 2021; 21(1):456.

Harms D, Zahn S, Göbel U, Schneider DT. Pathology and molecular biology of teratomas in childhood and adolescence. Klin Padiatr. 2006; 218(6):296-302.

Barksdale EM Jr, Obokhare I. Teratomas in infants and children. Curr Opin Pediatr. 2009;21(3):344-9.

Sohrabi C, Mathew G, Maria N, Kerwan A, Franchi T, Agha RA, et al. The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines. Int J Surg. 2023;109(5):1136-1140.

Heerema-McKenney A, Harrison MR, Bratton B, Farrell J, Zaloudek C. Congenital teratoma: a clinicopathologic study of 22 fetal and neonatal tumors. Am J Surg Pathol. 2005;29(1):29-38.

Rao R, Honavar SG, Mulay K. Primary lacrimal gland teratoma in an adult: A clinicopathologic and radiological correlation. Indian J Ophthalmol. 2019 ;67(7):1238-1240.

Alkatan HM, AlObaidan OS, Kfoury H, Al-Faky YH. Orbital immature teratoma: A rare entity with diagnostic challenges. Saudi J Ophthalmol. 2018;32(1):75-8.

Yang Z, Du L, Zhang H. Congenital orbital teratoma: A clinicopathologic case report. J Obstet Gynaecol Res. 2021;47(6):2225-9.

Dharmarajan H, Rouillard-Bazinet N, Chandy BM. Mature and immature pediatric head and neck teratomas: A 15-year review at a large tertiary center. Int J Pediatr Otorhinolaryngol. 2018;105:43-47.

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Published

2025-01-04

How to Cite

1.
Gregório Andreassa Soares, Samya Hamad Mehanna, Júlia Costa Linhares. Congenital immature orbital teratoma with sarcomatous transformation presenting as exophthalmos: A case report. J Neonatal Surg [Internet]. 2025Jan.4 [cited 2025Jan.15];14:3. Available from: https://jneonatalsurg.com/index.php/jns/article/view/1403

Issue

Vol. 14 (2025): Journal of Neonatal Surgery

Section

Case Report

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