Genetics and Orthodontics .

Authors

  • Nezar Watted
  • Ali Watted
  • Rand Ghoul
  • Iosif Amparat
  • Muhamad Abu Hussein

DOI:

https://doi.org/10.63682/jns.v15i1s.10454

Keywords:

History, dental anomalies, genetics, orthodontics

Abstract

Genetics explains a great deal of variation seen in the population when facial deformities and malocclusions are considered. However, genetics is not synonymous of a deterministic concept in which a single gene, segregating in families, determines malocclusion. These monogenic models explain very few cases of malocclusion and the other human diseases, as well as traits such as height, weight, amount of sugar in the circulating blood, blood pressure, intelligence, behavior, and sexual orientation. All these traits, as well as the majority of human diseases and congenital defects, have complex or multifactorial modes of inheritance, which can be influenced by the environment, and determine the presence of the majority of traits and diseases...

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References

1. Mencken HL. A Mencken chrestomathy. New York: A. A. Knopf, 1949.

2.Moss ML. The regulation of skeletal growth Regulation of Organ and Tissue Growth. Acad Press NY, 1972, 127-142.

3. King RA, Rotter JI, Motulsky AG. Approach to genetic basis of common diseases. Oxford Oxford University Press, 2002.

4. Gangane S. Human Genetics. 2nd ed New Delhi: Churchill Livingstone, 2000.

5. Bishara SE. Textbook of orthodontics, WB Saunders, 2001.

6. Abdulgani Azzaldeen. Genetics and Dental Disorders – A Clinical Concept. Part; 1. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS). 2017; 16(11):35-42.

7. Proffit WR. Contemporary orthodontics. 4th ed. St Louis:Mosby, 200

8. Ellis E and McNamara JA Jr. Components of adult class III malocclusion. J Oral and Maxillofac Surg. 1984;42: 295–305.

9. Graber TM, Vanarsdall RL, Vig KWL (eds). Orthodontics: Current principles and techniques, 4th edition, St. Louis, Mosby, 2005.

10. Harris JE. Genetic factors in the growth of the head: Inheritance of the craniofacial complex and malocclusion. Dent. Clin. North Am 1975;19:151–60.

11. Lundstrom A. Tooth size and occlusion in twins.m2nd ed. S Karger AG, Basle, 1948.

12. Lundstrom A. Some asymmetries of the dental arches, jaws and skull, and their etiological significance. Am J Orthod 1961;47:81-106.

13. Moyers RE. Handbook of orthodontics. 4th edition. Year book medical publishers, Inc. 1988.

14.Abu-Hussein M, Watted N, Yehia M, Proff P, Iraqi F. (Clinical Genetic Basis of Tooth Agenesis, Journal of Dental and Medical Sciences. 2015; 14(12):68-77. Doi: 10.9790/0853-141236877

15. Abu-Hussein M, Watted N, Yehia M, Proff P, Iraqi F. Clinical Genetic Basis of Tooth Agenesis, Journal of Dental and Medical Sciences. 2015; 14(12):68-77. Doi: 10.9790/0853-141236877

16. Proffit WR, Phillips C, Dann C IV. Who seeks surgical-orthodontic treatment? The characteristics of patients evaluated in the UNC Dentofacial Clinic. Int J Adult Orthod Orthognath Surg 1990;5:153-60.

17. Abu-Hussein Muhamad and Nezar Watted et al:(2019) “Genetics and Orthodontics”, International Journal of Applied Dental Sciences; 5(3): pp384-390

18. Abu-Hussein M, Watted N, et al; (2015) “Clinical Genetic Basis of Tooth Agenesis” Journal of Dental and Medical Sciences; 14(12): pp68-77.

19. Abdulgani Azzaldeen, et al; (2017) “Tooth Agenesis; Aetiological Factors”. Journal of Dental and Medical Sciences; 16(1): pp75-85

20. Abu-Hussein Muhamad and Nezar Watted, et al: (2019) “Genetics in pediatric dentistry: A review”, International Journal of Applied Dental Sciences; 5(3): pp401-408

21.. Kolomvos N, Azzaldeen A, et al; (2024) “Congenitally missing lateral incisors: Case management with a multidisciplinary approach”. J Adv Med Dent Scie Res;12(8): pp34-47.

22.Rand Ghoul, et al; (2025). “M Ultidisciplinary Approach To Treatment Of Midline Diastema”. Journal of Neonatal Surgery, 14 (22s) pp240-284

23.Hanali Abu Shilbayih, Nezar Watted, Muhamad Abu-Hussein (2016). “Multidisciplinary Aesthetic Dental Treatment; Peg lateral with Congenitally Maxillary lateral Incisors” -JDMS Volume 15, Issue 10 Ver. I PP 83-91

24. Qawasmeh Nour, Abdulgani Azzaldeen, et al; (2024). “Digital Technologies in Dentistry”. J Oral Dental Care;1(1): pp1-2.

25. Abu-Hussein Muhamad, Watted Nezar, et al;(2015) “The Curve of Dental Arch in Normal Occlusion”. Open Science Journal of Clinical Medicine. 3, 2, pp47-54

26. M. Abu-Hussein, Aspasia Sarafianou (2012). “Mathematical Analysis Of Dental Arch Of Children In Normal Occlusion: A Literature Review”. International Journal of Medical Dentistry,16,1, pp33-40

27.Abu-Hussein M.; Cleft Lip and Palate – Etiological Factors. Dent. Med. Probl. 2012, 49, 2, 149–156

28.Abu-Hussein M.; Cleft lips and palate ;the roles of specialists, Minerva Pediatr. 2011 .63(3):227-32.

29.Muhamad AH, Azzaldeen A (2012) Genetic of Non-syn- dromic Cleft Lip and Palate. 1:510.doi: 10.4172/scientificrep- orts. 510

30Muhamad Abu-Hussein, Nezar Watted, Viktória Hegedűs, Péter Borbély, Abdulgani Azzaldeen (2015); Human Genetic Factors In Non-Syndromic Cleft Lip And Palate: An Update International Journal Of Maxillofacial Research 1,3,7-23

31.Abu-Hussein M.; Cleft Lip and Palate – Etiological Factors. Dent. Med. Probl. 2012, 49, 2, 149– 156

32.Abu-Hussein M.; Cleft lips and palate the roles of specialists, Minerva Pediatr. 2011 .63(3):227-32

33.Abu-Hussein Muhamad, Abdulgani Azzaldeen and Nizar Wat- ted; CLEFT LIP AND PALATE; A COMPREHENSIVE RE- VIEW International Journal of Basic and Applied Medical Sci- ences 2014 Vol. 4 (1), 338-355

34.Abu-Hussein Muhamad, Abdulgani Azzaldeen, Watted Nezar, Kassem Firas. The Multifactorial Factors Influencing Cleft Lip- Literature Review. International Journal of Clinical Medicine Research. Vol. 1, No. 3, 2014, pp. 90-96

35. Cobourne MT, DiBiase AT. Handbook of orthodontics (1stedn), Elsevier, Edinburgh, London, Newyork,Oxford, Philadelphia, St Louis, Sydney, Toranto, 2009

36.M. Abu-Hussein, N. Watted, E. Hussien, A. Watted; Feeding Appliance for A Newborn Baby with Cleft Palate. Interna- tional Journal Dental and Medical Sciences Research Vol 1, 6 (Nov- 2017), 05-09

37. Muhamad AH, Azzaldeen A. Genetic of Non-syndromic Cleft Lip and Palate, 2012.1:510.doi:10.4172/scientificreports.510

38. Strachan T., Read A.P. Human Molecular Genetics, 2nd ed.; New York: Wiley-Liss,1999; Chapter 22.

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Published

2026-07-14

How to Cite

1.
Watted N, Watted A, Ghoul R, Amparat I, Abu Hussein M. Genetics and Orthodontics . J Neonatal Surg [Internet]. 2026 Jul. 14 [cited 2026 Jul. 18];15(1s):250-6. Available from: https://jneonatalsurg.com/index.php/jns/article/view/10454

Issue

Vol. 15 No. 1s (2026): Journal of Neonatal Surgery

Section

Original Article

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