Beyond Hydrocephalus: Colpocephaly Mimicking Neonatal Ventriculomegaly
Keywords:
Colpocephaly, Corpus Callosum, Lateral Ventricles, Children. .Abstract
Colpocephaly is the abnormal dilation of the posterior horns of the lateral ventricles. It is a congenital brain abnormality and is most often associated with partial or complete agenesis of the corpus callosum. A full term neonate was delivered at 39 weeks’ gestation by spontaneous vaginal delivery. Antenatal ultrasound had detected right sided ventriculomegaly. The neonate was admitted to the neonatal intensive care unit. He later developed mild respiratory distress. Cranial ultrasound on admission revealed marked ventriculomegaly, suggestive of communicating hydrocephalus. Brain MRI demonstrated global microcephaly, disproportionate ventricular dilation predominantly affecting the occipital horns, radiological features of colpocephaly, and dysgenesis of the corpus callosum. Electroencephalography showed a burst suppression pattern, consistent with epileptic encephalopathy and severe cerebral dysfunction. The infant was maintained on ad lib oral feeds. Mechanical ventilation was required for two days, and intravenous antibiotics were continued for two days. The neonate stabilized clinically and was discharged with antiepileptic therapy and close multidisciplinary follow-up...
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